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Items: 5


Diminished Canonical β-Catenin Signaling During Osteoblast Differentiation Contributes to Osteopenia in Progeria.

Choi JY, Lai JK, Xiong ZM, Ren M, Moorer MC, Stains JP, Cao K.

J Bone Miner Res. 2018 Nov;33(11):2059-2070. doi: 10.1002/jbmr.3549. Epub 2018 Aug 1.


Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.

Ibrahim MX, Sayin VI, Akula MK, Liu M, Fong LG, Young SG, Bergo MO.

Science. 2013 Jun 14;340(6138):1330-3. doi: 10.1126/science.1238880. Epub 2013 May 16.


Skeletal phenotype of mandibuloacral dysplasia associated with mutations in ZMPSTE24.

Cunningham VJ, D'Apice MR, Licata N, Novelli G, Cundy T.

Bone. 2010 Sep;47(3):591-7. doi: 10.1016/j.bone.2010.06.004. Epub 2010 Jun 13.


A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, Young SG.

Science. 2006 Mar 17;311(5767):1621-3. Epub 2006 Feb 16.


Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.

Bergo MO, Gavino B, Ross J, Schmidt WK, Hong C, Kendall LV, Mohr A, Meta M, Genant H, Jiang Y, Wisner ER, Van Bruggen N, Carano RA, Michaelis S, Griffey SM, Young SG.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13049-54. Epub 2002 Sep 16.

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