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Items: 16


Overexpression of SOX9 alleviates the progression of human osteoarthritis in vitro and in vivo.

Ouyang Y, Wang W, Tu B, Zhu Y, Fan C, Li Y.

Drug Des Devel Ther. 2019 Aug 13;13:2833-2842. doi: 10.2147/DDDT.S203974. eCollection 2019.


Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase.

Ehnert S, Linnemann C, Aspera-Werz RH, Bykova D, Biermann S, Fecht L, De Zwart PM, Nussler AK, Stuby F.

Int J Mol Sci. 2018 Jul 31;19(8). pii: E2239. doi: 10.3390/ijms19082239.


Small molecule inhibitor RepSox prevented ovariectomy-induced osteoporosis by suppressing osteoclast differentiation and bone resorption.

Mei L, Sang W, Chen Z, Zheng L, Jin K, Lou C, Huang W, He D.

J Cell Physiol. 2018 Dec;233(12):9724-9738. doi: 10.1002/jcp.26914. Epub 2018 Jul 30.


MiR-181d promotes steroid-induced osteonecrosis of the femoral head by targeting SMAD3 to inhibit osteogenic differentiation of hBMSCs.

Xie Y, Hu JZ, Shi ZY.

Eur Rev Med Pharmacol Sci. 2018 Jul;22(13):4053-4062. doi: 10.26355/eurrev_201807_15393.


Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model.

Regan JN, Mikesell C, Reiken S, Xu H, Marks AR, Mohammad KS, Guise TA, Waning DL.

Front Endocrinol (Lausanne). 2017 Dec 19;8:358. doi: 10.3389/fendo.2017.00358. eCollection 2017.


Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway.

Aref-Eshghi E, Liu M, Harper PE, Doré J, Martin G, Furey A, Green R, Rahman P, Zhai G.

Arthritis Res Ther. 2015 Sep 23;17:264. doi: 10.1186/s13075-015-0788-x.


Sulfuretin induces osteoblast differentiation through activation of TGF-β signaling.

Song NJ, Kwon SM, Kim S, Yoon HJ, Seo CR, Jang B, Chang SH, Ku JM, Lee JS, Park KM, Hong JW, Kim GH, Park KW.

Mol Cell Biochem. 2015 Dec;410(1-2):55-63. doi: 10.1007/s11010-015-2537-5. Epub 2015 Aug 11.


Downregulated interleukin 37 expression associated with aggravation of intervertebral disc degeneration.

Wan ZY, Sun Z, Song F, Chen YF, Zhang WL, Wang HQ, Luo ZJ.

Int J Clin Exp Pathol. 2014 Jan 15;7(2):656-62. eCollection 2014.


Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing.

Kawakatsu M, Kanno S, Gui T, Gai Z, Itoh S, Tanishima H, Oikawa K, Muragaki Y.

Exp Mol Pathol. 2011 Feb;90(1):107-15. doi: 10.1016/j.yexmp.2010.10.011. Epub 2010 Oct 28.


Effect of gypsum on proliferation and differentiation of MC3T3-E1 mouse osteoblastic cells.

Lazáry A, Balla B, Kósa JP, Bácsi K, Nagy Z, Takács I, Varga PP, Speer G, Lakatos P.

Biomaterials. 2007 Jan;28(3):393-9. Epub 2006 Sep 25.


TGF-beta regulates the mechanical properties and composition of bone matrix.

Balooch G, Balooch M, Nalla RK, Schilling S, Filvaroff EH, Marshall GW, Marshall SJ, Ritchie RO, Derynck R, Alliston T.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18813-8. Epub 2005 Dec 14.


Mutation analysis of the Smad3 gene in human osteoarthritis.

Yao JY, Wang Y, An J, Mao CM, Hou N, Lv YX, Wang YL, Cui F, Huang M, Yang X.

Eur J Hum Genet. 2003 Sep;11(9):714-7.


The ratio of osteocytic incorporation to bone matrix formation in femoral neck cancellous bone: an enhanced osteoblast work rate in the vicinity of hip osteoarthritis.

Jordan GR, Loveridge N, Power J, Clarke MT, Parker M, Reeve J.

Calcif Tissue Int. 2003 Mar;72(3):190-6. Epub 2003 Jan 21.


TGF-beta, BMPS, and their signal transducing mediators, Smads, in rat fracture healing.

Yu Y, Yang JL, Chapman-Sheath PJ, Walsh WR.

J Biomed Mater Res. 2002 Jun 5;60(3):392-7.


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