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Items: 14

1.

The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis.

Shen GS, Zhou HB, Zhang H, Chen B, Liu ZP, Yuan Y, Zhou XZ, Xu YJ.

Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3644-3654. doi: 10.1016/j.bbadis.2018.09.015. Epub 2018 Sep 14.

PMID:
30279140
2.

Deletion of ferroportin in murine myeloid cells increases iron accumulation and stimulates osteoclastogenesis in vitro and in vivo.

Wang L, Fang B, Fujiwara T, Krager K, Gorantla A, Li C, Feng JQ, Jennings ML, Zhou J, Aykin-Burns N, Zhao H.

J Biol Chem. 2018 Jun 15;293(24):9248-9264. doi: 10.1074/jbc.RA117.000834. Epub 2018 May 3.

3.

PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption.

Stechschulte LA, Czernik PJ, Rotter ZC, Tausif FN, Corzo CA, Marciano DP, Asteian A, Zheng J, Bruning JB, Kamenecka TM, Rosen CJ, Griffin PR, Lecka-Czernik B.

EBioMedicine. 2016 Aug;10:174-84. doi: 10.1016/j.ebiom.2016.06.040. Epub 2016 Jun 29.

4.

Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.

Herlin M, McGuigan FE, Luthman H, Åkesson K.

Bone. 2015 Oct;79:105-9. doi: 10.1016/j.bone.2015.05.035. Epub 2015 May 30.

PMID:
26036173
5.

Dietary calcium deficiency and excess both impact bone development and mesenchymal stem cell lineage priming in neonatal piglets.

Li Y, Stahl CH.

J Nutr. 2014 Dec;144(12):1935-42. doi: 10.3945/jn.114.194787. Epub 2014 Oct 15.

PMID:
25320190
6.

The association between genetic variants of RUNX2, ADIPOQ and vertebral fracture in Korean postmenopausal women.

Kim KC, Chun H, Lai C, Parnell LD, Jang Y, Lee J, Ordovas JM.

J Bone Miner Metab. 2015 Mar;33(2):173-9. doi: 10.1007/s00774-014-0570-1. Epub 2014 Feb 26.

PMID:
24570271
7.

Current clinical evidence on pioglitazone pharmacogenomics.

Kawaguchi-Suzuki M, Frye RF.

Front Pharmacol. 2013 Nov 26;4:147. doi: 10.3389/fphar.2013.00147. eCollection 2013.

8.

Hypoxia promotes osteogenesis but suppresses adipogenesis of human mesenchymal stromal cells in a hypoxia-inducible factor-1 dependent manner.

Wagegg M, Gaber T, Lohanatha FL, Hahne M, Strehl C, Fangradt M, Tran CL, Schönbeck K, Hoff P, Ode A, Perka C, Duda GN, Buttgereit F.

PLoS One. 2012;7(9):e46483. doi: 10.1371/journal.pone.0046483. Epub 2012 Sep 27.

9.

PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: a pilot study.

Dragojevič J, Ostanek B, Mencej-Bedrač S, Komadina R, Preželj J, Marc J.

Clin Biochem. 2011 Sep;44(13):1085-1089. doi: 10.1016/j.clinbiochem.2011.06.981. Epub 2011 Jul 6.

PMID:
21756892
10.

Polymorphisms of the peroxisome proliferator-activated receptor γ (PPARγ) gene are associated with osteoporosis.

Harsløf T, Tofteng CL, Husted LB, Nyegaard M, Børglum A, Carstens M, Stenkjær L, Brixen K, Eiken P, Jensen JE, Mosekilde L, Rejnmark L, Langdahl BL.

Osteoporos Int. 2011 Oct;22(10):2655-66. doi: 10.1007/s00198-010-1491-z. Epub 2010 Nov 23.

PMID:
21104228
11.

Expression of genes associated with bone resorption is increased and bone formation is decreased in mice fed a high-fat diet.

Xiao Y, Cui J, Li YX, Shi YH, Le GW.

Lipids. 2010 Apr;45(4):345-55. doi: 10.1007/s11745-010-3397-0. Epub 2010 Mar 7.

PMID:
20213531
12.

PPARG by dietary fat interaction influences bone mass in mice and humans.

Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ.

J Bone Miner Res. 2008 Sep;23(9):1398-408. doi: 10.1359/jbmr.080419.

13.

Genome-wide association with bone mass and geometry in the Framingham Heart Study.

Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S14.

14.

The Genetics of PPARG and the Skeleton.

Ackert-Bicknell C, Rosen C.

PPAR Res. 2006;2006:93258.

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