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Items: 1 to 20 of 150

1.

An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline.

Frøkjær-Jensen C, Jain N, Hansen L, Davis MW, Li Y, Zhao D, Rebora K, Millet JR, Liu X, Kim SK, Dupuy D, Jorgensen EM, Fire AZ.

Cell. 2016 Jul 14;166(2):343-57. doi: 10.1016/j.cell.2016.05.072.

PMID:
27374334
2.

Translation readthrough mitigation.

Arribere JA, Cenik ES, Jain N, Hess GT, Lee CH, Bassik MC, Fire AZ.

Nature. 2016 Jun 30;534(7609):719-23.

3.

Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo.

Fu BX, St Onge RP, Fire AZ, Smith JD.

Nucleic Acids Res. 2016 Jun 20;44(11):5365-77. doi: 10.1093/nar/gkw417.

4.

A streamlined tethered chromosome conformation capture protocol.

Gabdank I, Ramakrishnan S, Villeneuve AM, Fire AZ.

BMC Genomics. 2016 Apr 1;17:274. doi: 10.1186/s12864-016-2596-3.

5.

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.

Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, Kumar A, Lu X, Luo K, Mangiapani MC, Parks RJ, Song H, Acharya P, Bailer RT, Cao A, Druz A, Georgiev IS, Kwon YD, Louder MK, Zhang B, Zheng A, Hill BJ, Kong R, Soto C; NISC Comparative Sequencing Program., Mullikin JC, Douek DC, Montefiori DC, Moody MA, Shaw GM, Hahn BH, Kelsoe G, Hraber PT, Korber BT, Boyd SD, Fire AZ, Kepler TB, Shapiro L, Ward AB, Mascola JR, Liao HX, Kwong PD, Haynes BF.

Cell. 2016 Apr 7;165(2):449-63. doi: 10.1016/j.cell.2016.02.022.

PMID:
26949186
6.

Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase-Cas1 fusion protein.

Silas S, Mohr G, Sidote DJ, Markham LM, Sanchez-Amat A, Bhaya D, Lambowitz AM, Fire AZ.

Science. 2016 Feb 26;351(6276):aad4234. doi: 10.1126/science.aad4234.

7.

Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans.

Bell RT, Fu BX, Fire AZ.

Genetics. 2016 Feb;202(2):381-8. doi: 10.1534/genetics.115.185041. Erratum in: Genetics. 2016 Jun;203(2):999.

8.

Chikungunya Virus Sequences Across the First Epidemic in Nicaragua, 2014-2015.

Wang C, Saborio S, Gresh L, Eswarappa M, Wu D, Fire A, Parameswaran P, Balmaseda A, Harris E.

Am J Trop Med Hyg. 2016 Feb;94(2):400-3. doi: 10.4269/ajtmh.15-0497.

9.

Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species.

Nakatani Y, Mello CC, Hashimoto S, Shimada A, Nakamura R, Tsukahara T, Qu W, Yoshimura J, Suzuki Y, Sugano S, Takeda H, Fire A, Morishita S.

BMC Genomics. 2015 Nov 19;16:978. doi: 10.1186/s12864-015-2198-5.

10.

Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

Levin M, King JJ, Glanville J, Jackson KJ, Looney TJ, Hoh RA, Mari A, Andersson M, Greiff L, Fire AZ, Boyd SD, Ohlin M.

J Allergy Clin Immunol. 2016 May;137(5):1535-44. doi: 10.1016/j.jaci.2015.09.027.

PMID:
26559321
11.
12.

A requirement for ERK-dependent Dicer phosphorylation in coordinating oocyte-to-embryo transition in C. elegans.

Drake M, Furuta T, Suen KM, Gonzalez G, Liu B, Kalia A, Ladbury JE, Fire AZ, Skeath JB, Arur S.

Dev Cell. 2014 Dec 8;31(5):614-28. doi: 10.1016/j.devcel.2014.11.004.

13.

Landscape of target:guide homology effects on Cas9-mediated cleavage.

Fu BX, Hansen LL, Artiles KL, Nonet ML, Fire AZ.

Nucleic Acids Res. 2014 Dec 16;42(22):13778-87. doi: 10.1093/nar/gku1102.

14.

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.

Kepler TB, Liao HX, Alam SM, Bhaskarabhatla R, Zhang R, Yandava C, Stewart S, Anasti K, Kelsoe G, Parks R, Lloyd KE, Stolarchuk C, Pritchett J, Solomon E, Friberg E, Morris L, Karim SS, Cohen MS, Walter E, Moody MA, Wu X, Altae-Tran HR, Georgiev IS, Kwong PD, Boyd SD, Fire AZ, Mascola JR, Haynes BF.

Cell Host Microbe. 2014 Sep 10;16(3):304-13. doi: 10.1016/j.chom.2014.08.006.

15.

Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans.

Arribere JA, Bell RT, Fu BX, Artiles KL, Hartman PS, Fire AZ.

Genetics. 2014 Nov;198(3):837-46. doi: 10.1534/genetics.114.169730.

16.

Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements.

Jackson KJ, Liu Y, Roskin KM, Glanville J, Hoh RA, Seo K, Marshall EL, Gurley TC, Moody MA, Haynes BF, Walter EB, Liao HX, Albrecht RA, García-Sastre A, Chaparro-Riggers J, Rajpal A, Pons J, Simen BB, Hanczaruk B, Dekker CL, Laserson J, Koller D, Davis MM, Fire AZ, Boyd SD.

Cell Host Microbe. 2014 Jul 9;16(1):105-14. doi: 10.1016/j.chom.2014.05.013.

17.

Effects of aging, cytomegalovirus infection, and EBV infection on human B cell repertoires.

Wang C, Liu Y, Xu LT, Jackson KJ, Roskin KM, Pham TD, Laserson J, Marshall EL, Seo K, Lee JY, Furman D, Koller D, Dekker CL, Davis MM, Fire AZ, Boyd SD.

J Immunol. 2014 Jan 15;192(2):603-11. doi: 10.4049/jimmunol.1301384.

18.

Unusual DNA packaging characteristics in endoreduplicated Caenorhabditis elegans oocytes defined by in vivo accessibility to an endogenous nuclease activity.

Gu S, Goszczynski B, McGhee JD, Fire AZ.

Epigenetics Chromatin. 2013 Nov 1;6(1):37. doi: 10.1186/1756-8935-6-37.

19.

Gamete-type dependent crossover interference levels in a defined region of Caenorhabditis elegans chromosome V.

Gabdank I, Fire AZ.

G3 (Bethesda). 2014 Jan 10;4(1):117-20. doi: 10.1534/g3.113.008672.

20.

Conserved translatome remodeling in nematode species executing a shared developmental transition.

Stadler M, Fire A.

PLoS Genet. 2013;9(10):e1003739. doi: 10.1371/journal.pgen.1003739.

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