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Mechanism of the anti-angiogenic effect of Avemar on tumor cells.

Imir NG, Aydemir E, Şimşek E.

Oncol Lett. 2018 Feb;15(2):2673-2678. doi: 10.3892/ol.2017.7604. Epub 2017 Dec 13.


A purified, fermented, extract of Triticum aestivum has lymphomacidal activity mediated via natural killer cell activation.

Barisone GA, O'Donnell RT, Ma Y, Abuhay MW, Lundeberg K, Gowda S, Tuscano JM.

PLoS One. 2018 Jan 5;13(1):e0190860. doi: 10.1371/journal.pone.0190860. eCollection 2018.


Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats.

Akinrinmade O, Omoruyi S, Dietrich D, Ekpo O.

Acta Neurobiol Exp (Wars). 2017;77(1):94-105.


Antiproliferative and antimetabolic effects behind the anticancer property of fermented wheat germ extract.

Otto C, Hahlbrock T, Eich K, Karaaslan F, Jürgens C, Germer CT, Wiegering A, Kämmerer U.

BMC Complement Altern Med. 2016 Jun 1;16:160. doi: 10.1186/s12906-016-1138-5.


Inhibitory Effects of AVEMAR on Proliferation and Metastasis of Oral Cancer Cells.

Yang MD, Chang WS, Tsai CW, Wang MF, Chan YC, Chan KC, Lu MC, Kao AW, Hsu CM, Bau DT.

Nutr Cancer. 2016;68(3):473-80. doi: 10.1080/01635581.2016.1153668. Epub 2016 Mar 23.


Antitumor Activities and Apoptosis-regulated Mechanisms of Fermented Wheat Germ Extract in the Transplantation Tumor Model of Human HT-29 Cells in Nude Mice.

Zhang JY, Xiao X, Dong Y, Wu J, Zhou XH.

Biomed Environ Sci. 2015 Oct;28(10):718-27. doi: 10.3967/bes2015.102.


Avemar and Echinacea extracts enhance mobilization and homing of CD34(+) stem cells in rats with acute myocardial infarction.

Abdelmonem M, Kassem SH, Gabr H, Shaheen AA, Aboushousha T.

Stem Cell Res Ther. 2015 Sep 14;6:172. doi: 10.1186/s13287-015-0171-5.


The Medical Use of Wheatgrass: Review of the Gap Between Basic and Clinical Applications.

Bar-Sela G, Cohen M, Ben-Arye E, Epelbaum R.

Mini Rev Med Chem. 2015;15(12):1002-10. Review.


Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells.

Wang CW, Wang CK, Chang YJ, Choong CY, Lin CS, Tai CJ, Tai CJ.

Evid Based Complement Alternat Med. 2015;2015:570785. doi: 10.1155/2015/570785. Epub 2015 Mar 1.


Effect of fermented wheat germ extract with lactobacillus plantarum dy-1 on HT-29 cell proliferation and apoptosis.

Zhang JY, Xiao X, Dong Y, Wu J, Yao F, Zhou XH.

J Agric Food Chem. 2015 Mar 11;63(9):2449-57. doi: 10.1021/acs.jafc.5b00041. Epub 2015 Mar 2.


Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.

Shibuya N, Inoue K, Tanaka G, Akimoto K, Kubota K.

Oncology. 2015;88(5):309-19. doi: 10.1159/000369905. Epub 2015 Jan 14.


Fermented wheat germ extract induced cell death and enhanced cytotoxicity of Cisplatin and 5-Fluorouracil on human hepatocellular carcinoma cells.

Tai CJ, Wang WC, Wang CK, Wu CH, Yang MD, Chang YJ, Jian JY, Tai CJ.

Evid Based Complement Alternat Med. 2013;2013:121725. doi: 10.1155/2013/121725. Epub 2013 Dec 22.


Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity.

Judson PL, Al Sawah E, Marchion DC, Xiong Y, Bicaku E, Bou Zgheib N, Chon HS, Stickles XB, Hakam A, Wenham RM, Apte SM, Gonzalez-Bosquet J, Chen DT, Lancaster JM.

Int J Gynecol Cancer. 2012 Jul;22(6):960-7. doi: 10.1097/IGC.0b013e318258509d.


The effectiveness of fermented wheat germ extract as an adjunct therapy in the treatment of cancer: A systematic review.

Yeend T, Robinson K, Lockwood C, McArthur A.

JBI Libr Syst Rev. 2012;10(42 Suppl):1-12.


Fermented wheat germ extract--nutritional supplement or anticancer drug?

Mueller T, Voigt W.

Nutr J. 2011 Sep 5;10:89. doi: 10.1186/1475-2891-10-89.


Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines.

Mueller T, Jordan K, Voigt W.

J Exp Clin Cancer Res. 2011 Apr 16;30:42. doi: 10.1186/1756-9966-30-42.


Avemar (wheat germ extract) in cancer prevention and treatment.

Telekes A, Hegedus M, Chae CH, Vékey K.

Nutr Cancer. 2009;61(6):891-9. doi: 10.1080/01635580903285114.


Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats.

Iyer A, Brown L.

Evid Based Complement Alternat Med. 2011;2011:508957. doi: 10.1093/ecam/nep090. Epub 2011 Jan 4.


Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis.

Saiko P, Ozsvar-Kozma M, Graser G, Lackner A, Grusch M, Madlener S, Krupitza G, Jaeger W, Hidvegi M, Agarwal RP, Fritzer-Szekeres M, Szekeres T.

Oncol Rep. 2009 Mar;21(3):787-91.


Adjuvant fermented wheat germ extract (Avemar) nutraceutical improves survival of high-risk skin melanoma patients: a randomized, pilot, phase II clinical study with a 7-year follow-up.

Demidov LV, Manziuk LV, Kharkevitch GY, Pirogova NA, Artamonova EV.

Cancer Biother Radiopharm. 2008 Aug;23(4):477-82. doi: 10.1089/cbr.2008.0486. Erratum in: Cancer Biother Radiopharm. 2008 Oct;23(5):669.


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