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Items: 1 to 20 of 30

1.

Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.

Bencsik P, Kupai K, Görbe A, Kenyeres É, Varga ZV, Pálóczi J, Gáspár R, Kovács L, Weber L, Takács F, Hajdú I, Fabó G, Cseh S, Barna L, Csont T, Csonka C, Dormán G, Ferdinandy P.

Front Pharmacol. 2018 Apr 5;9:296. doi: 10.3389/fphar.2018.00296. eCollection 2018.

2.

Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model.

Kemény Á, Csekő K, Szitter I, Varga ZV, Bencsik P, Kiss K, Halmosi R, Deres L, Erős K, Perkecz A, Kereskai L, László T, Kiss T, Ferdinandy P, Helyes Z.

Environ Pollut. 2017 Oct;229:746-759. doi: 10.1016/j.envpol.2017.04.098. Epub 2017 Jun 22.

PMID:
28648837
3.

MMP Activity Detection in Zymograms.

Bencsik P, Bartekova M, Görbe A, Kiss K, Pálóczi J, Radosinska J, Szűcs G, Ferdinandy P.

Methods Mol Biol. 2017;1626:53-70. doi: 10.1007/978-1-4939-7111-4_6.

PMID:
28608200
4.

Low-Dose Endotoxin Induces Late Preconditioning, Increases Peroxynitrite Formation, and Activates STAT3 in the Rat Heart.

Pipicz M, Kocsis GF, Sárváry-Arantes L, Bencsik P, Varga ZV, Ferdinandy P, Csont T.

Molecules. 2017 Mar 8;22(3). pii: E433. doi: 10.3390/molecules22030433.

5.

Specific Mechanisms Underlying Right Heart Failure: The Missing Upregulation of Superoxide Dismutase-2 and Its Decisive Role in Antioxidative Defense.

Schreckenberg R, Rebelo M, Deten A, Weber M, Rohrbach S, Pipicz M, Csonka C, Ferdinandy P, Schulz R, Schlüter KD.

Antioxid Redox Signal. 2015 Nov 20;23(15):1220-32. doi: 10.1089/ars.2014.6139. Epub 2015 Jun 18.

6.

Serum lipids and cardiac function correlate with nitrotyrosine and MMP activity in coronary artery disease patients.

Bencsik P, Sasi V, Kiss K, Kupai K, Kolossváry M, Maurovich-Horvat P, Csont T, Ungi I, Merkely B, Ferdinandy P.

Eur J Clin Invest. 2015 Jul;45(7):692-701. doi: 10.1111/eci.12458. Epub 2015 Jun 1.

PMID:
25944577
7.

Activation of PPARβ/δ protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases.

Barlaka E, Görbe A, Gáspár R, Pálóczi J, Ferdinandy P, Lazou A.

Pharmacol Res. 2015 May-Jun;95-96:102-10. doi: 10.1016/j.phrs.2015.03.008. Epub 2015 Mar 28.

PMID:
25828396
8.

Moderate inhibition of myocardial matrix metalloproteinase-2 by ilomastat is cardioprotective.

Bencsik P, Pálóczi J, Kocsis GF, Pipis J, Belecz I, Varga ZV, Csonka C, Görbe A, Csont T, Ferdinandy P.

Pharmacol Res. 2014 Feb;80:36-42. doi: 10.1016/j.phrs.2013.12.007. Epub 2013 Dec 28.

PMID:
24380772
9.

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart.

Varga ZV, Kupai K, Szűcs G, Gáspár R, Pálóczi J, Faragó N, Zvara A, Puskás LG, Rázga Z, Tiszlavicz L, Bencsik P, Görbe A, Csonka C, Ferdinandy P, Csont T.

J Mol Cell Cardiol. 2013 Sep;62:111-21. doi: 10.1016/j.yjmcc.2013.05.009. Epub 2013 May 27.

PMID:
23722270
10.

Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats.

Szucs G, Bester DJ, Kupai K, Csont T, Csonka C, Esterhuyse AJ, Ferdinandy P, Van Rooyen J.

Lipids Health Dis. 2011 Jun 20;10:103. doi: 10.1186/1476-511X-10-103.

11.

Role of iNOS and peroxynitrite-matrix metalloproteinase-2 signaling in myocardial late preconditioning in rats.

Bencsik P, Kupai K, Giricz Z, Görbe A, Pipis J, Murlasits Z, Kocsis GF, Varga-Orvos Z, Puskás LG, Csonka C, Csont T, Ferdinandy P.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H512-8. doi: 10.1152/ajpheart.00052.2010. Epub 2010 Jun 11.

12.

Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite.

Kupai K, Csonka C, Fekete V, Odendaal L, van Rooyen J, Marais de W, Csont T, Ferdinandy P.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1729-35. doi: 10.1152/ajpheart.00484.2009. Epub 2009 Sep 4.

13.

Cardiac capsaicin-sensitive sensory nerves regulate myocardial relaxation via S-nitrosylation of SERCA: role of peroxynitrite.

Bencsik P, Kupai K, Giricz Z, Görbe A, Huliák I, Fürst S, Dux L, Csont T, Jancsó G, Ferdinandy P.

Br J Pharmacol. 2008 Feb;153(3):488-96. Epub 2007 Nov 26.

14.

Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice.

Csont T, Bereczki E, Bencsik P, Fodor G, Görbe A, Zvara A, Csonka C, Puskás LG, Sántha M, Ferdinandy P.

Cardiovasc Res. 2007 Oct 1;76(1):100-9. Epub 2007 Jun 19.

PMID:
17658498
15.

Enhanced hit-to-lead process using bioanalogous lead evolution and chemogenomics: application in designing selective matrix metalloprotease inhibitors.

Papp A, Szommer T, Barna L, Gyimesi G, Ferdinandy P, Spadoni C, Darvas F, Fujita T, Urge L, Dormán G.

Expert Opin Drug Discov. 2007 May;2(5):707-23. doi: 10.1517/17460441.2.5.707.

PMID:
23488960
16.

Peroxynitrite: just an oxidative/nitrosative stressor or a physiological regulator as well?

Ferdinandy P.

Br J Pharmacol. 2006 May;148(1):1-3. No abstract available.

17.

The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.

Turan N, Csonka C, Csont T, Giricz Z, Fodor G, Bencsik P, Gyöngyösi M, Cakici I, Ferdinandy P.

Cardiovasc Res. 2006 May 1;70(2):384-90. Epub 2006 Jan 27.

PMID:
16443208
18.

Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.

Giricz Z, Lalu MM, Csonka C, Bencsik P, Schulz R, Ferdinandy P.

J Pharmacol Exp Ther. 2006 Jan;316(1):154-61. Epub 2005 Sep 15.

19.

Hyperlipidemia induced by a cholesterol-rich diet leads to enhanced peroxynitrite formation in rat hearts.

Onody A, Csonka C, Giricz Z, Ferdinandy P.

Cardiovasc Res. 2003 Jun 1;58(3):663-70.

PMID:
12798440
20.

Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.

Gao CQ, Sawicki G, Suarez-Pinzon WL, Csont T, Wozniak M, Ferdinandy P, Schulz R.

Cardiovasc Res. 2003 Feb;57(2):426-33.

PMID:
12566115

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