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Items: 9


Structural basis of 7SK RNA 5'-γ-phosphate methylation and retention by MePCE.

Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J.

Nat Chem Biol. 2019 Feb;15(2):132-140. doi: 10.1038/s41589-018-0188-z. Epub 2018 Dec 17.


Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.

Eichhorn CD, Yang Y, Repeta L, Feigon J.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6457-E6466. doi: 10.1073/pnas.1806276115. Epub 2018 Jun 26.


hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA.

Eichhorn CD, Chug R, Feigon J.

Nucleic Acids Res. 2016 Nov 16;44(20):9977-9989. Epub 2016 Sep 26.


Structure and function of preQ1 riboswitches.

Eichhorn CD, Kang M, Feigon J.

Biochim Biophys Acta. 2014 Oct;1839(10):939-950. doi: 10.1016/j.bbagrm.2014.04.019. Epub 2014 May 4. Review.


Structural dynamics of a single-stranded RNA-helix junction using NMR.

Eichhorn CD, Al-Hashimi HM.

RNA. 2014 Jun;20(6):782-91. doi: 10.1261/rna.043711.113. Epub 2014 Apr 17.


Structural determinants for ligand capture by a class II preQ1 riboswitch.

Kang M, Eichhorn CD, Feigon J.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E663-71. doi: 10.1073/pnas.1400126111. Epub 2014 Jan 27.


Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure.

Suddala KC, Rinaldi AJ, Feng J, Mustoe AM, Eichhorn CD, Liberman JA, Wedekind JE, Al-Hashimi HM, Brooks CL 3rd, Walter NG.

Nucleic Acids Res. 2013 Dec;41(22):10462-75. doi: 10.1093/nar/gkt798. Epub 2013 Sep 3.


Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy.

Bothe JR, Nikolova EN, Eichhorn CD, Chugh J, Hansen AL, Al-Hashimi HM.

Nat Methods. 2011 Oct 28;8(11):919-31. doi: 10.1038/nmeth.1735. Review.


Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.

Eichhorn CD, Feng J, Suddala KC, Walter NG, Brooks CL 3rd, Al-Hashimi HM.

Nucleic Acids Res. 2012 Feb;40(3):1345-55. doi: 10.1093/nar/gkr833. Epub 2011 Oct 18.

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