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Items: 1 to 20 of 235

1.

Secondary thrombotic microangiopathy in systemic lupus erythematosus and antiphospholipid syndrome, the role of complement and use of eculizumab: Case series and review of literature.

Kello N, Khoury LE, Marder G, Furie R, Zapantis E, Horowitz DL.

Semin Arthritis Rheum. 2018 Dec 4. pii: S0049-0172(18)30493-1. doi: 10.1016/j.semarthrit.2018.11.005. [Epub ahead of print]

PMID:
30598332
2.

Renal involvement in paroxysmal nocturnal haemoglobinuria: a brief review of the literature.

Macedo ÊS, Parente Filho SLA, Pro JDZ, Rolim VM, Primo GAS, Brunetta DM, Silva HFD, Meneses GC, Barroso-Duarte F, Daher EF.

Rev Assoc Med Bras (1992). 2018 Dec;64(12):1139-1146. doi: 10.1590/1806-9282.64.12.1139.

3.

CHAPLE syndrome uncovers the primary role of complement in a familial form of Waldmann's disease.

Ozen A.

Immunol Rev. 2019 Jan;287(1):20-32. doi: 10.1111/imr.12715. Review.

PMID:
30565236
4.

Complement-driven anemia: more than just paroxysmal nocturnal hemoglobinuria.

Merrill SA, Brodsky RA.

Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):371-376. doi: 10.1182/asheducation-2018.1.371. Review.

PMID:
30504334
5.

Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study.

Lee JW, Sicre de Fontbrune F, Wong Lee Lee L, Pessoa V, Gualandro S, Füreder W, Ptushkin V, Rottinghaus ST, Volles L, Shafner L, Aguzzi R, Pradhan R, Schrezenmeier H, Hill A.

Blood. 2018 Dec 3. pii: blood-2018-09-876136. doi: 10.1182/blood-2018-09-876136. [Epub ahead of print]

PMID:
30510080
6.

Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor-experienced adult patients with PNH: the 302 study.

Kulasekararaj AG, Hill A, Rottinghaus ST, Langemeijer S, Wells R, Gonzalez-Fernandez FA, Gaya A, Lee JW, Ojeda Gutierrez E, Piatek CI, Szer J, Risitano A, Nakao S, Bachman E, Shafner L, Damokosh AI, Ortiz S, Röth A, Peffault de Latour R.

Blood. 2018 Dec 3. pii: blood-2018-09-876805. doi: 10.1182/blood-2018-09-876805. [Epub ahead of print]

PMID:
30510079
7.

Effectiveness of eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) with or without aplastic anemia in the International PNH Registry.

Lee JW, Peffault de Latour R, Brodsky RA, Jang JH, Hill A, Röth A, Schrezenmeier H, Wilson A, Marantz JL, Maciejewski JP.

Am J Hematol. 2019 Jan;94(1):E37-E41. doi: 10.1002/ajh.25334. Epub 2018 Nov 25. No abstract available.

PMID:
30370949
8.

Complement activation by human red blood cell antibodies: hemolytic potential of antibodies and efficacy of complement inhibitors assessed by a sensitive flow cytometric assay.

Anliker M, Schmidt CQ, Harder MJ, Ganchev G, von Zabern I, Höchsmann B, Schrezenmeier H, Weinstock C.

Transfusion. 2018 Dec;58(12):2992-3002. doi: 10.1111/trf.14893. Epub 2018 Oct 27.

PMID:
30367826
9.

Recurrent aseptic meningitis with PIGT mutations: a novel pathogenesis of recurrent meningitis successfully treated by eculizumab.

Kawamoto M, Murakami Y, Kinoshita T, Kohara N.

BMJ Case Rep. 2018 Sep 27;2018. pii: bcr-2018-225910. doi: 10.1136/bcr-2018-225910.

10.

How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry.

Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B.

Eur J Haematol. 2019 Jan;102(1):36-52. doi: 10.1111/ejh.13176. Epub 2018 Oct 25. Review.

PMID:
30242915
11.

Therapeutic challenges in pregnant women with paroxysmal nocturnal hemoglobinuria: A case report.

Bastos JMC, Pinheiro PL, Rocha LC, Bicalho EC, Cazeli AB, Marcondes SS, Pinasco GC.

Medicine (Baltimore). 2018 Sep;97(36):e12155. doi: 10.1097/MD.0000000000012155.

12.

The Role of Whole-Body Magnetic Resonance Imaging (WB-MRI) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH).

Alashkar F, Schemuth HP, Nensa F, Göbel J, Vance C, Forsting M, Dührsen U, Schlosser TW, Röth A.

Sci Rep. 2018 Sep 7;8(1):13458. doi: 10.1038/s41598-018-31547-7.

13.

Paroxysmal nocturnal hemoglobinuria.

Čermák J.

Vnitr Lek. 2018 Summer;64(5):508-513.

PMID:
30193519
14.

[Paroxysmal nocturnal hemoglobinuria and thrombosis in the era of eculizumab].

Nishimura JI.

Rinsho Ketsueki. 2018;59(8):1042-1047. doi: 10.11406/rinketsu.59.1042. Japanese.

PMID:
30185704
15.

Diagnosis and management of PNH: Review and recommendations from a Belgian expert panel.

Devos T, Meers S, Boeckx N, Gothot A, Deeren D, Chatelain B, Chatelain C, Devalet B.

Eur J Haematol. 2018 Dec;101(6):737-749. doi: 10.1111/ejh.13166. Epub 2018 Oct 23. Review.

PMID:
30171728
16.

Ravulizumab (ALXN1210) in patients with paroxysmal nocturnal hemoglobinuria: results of 2 phase 1b/2 studies.

Röth A, Rottinghaus ST, Hill A, Bachman ES, Kim JS, Schrezenmeier H, Terriou L, Urbano-Ispizua Á, Wells RA, Jang JH, Kulasekararaj AG, Szer J, Aguzzi R, Damokosh AI, Shafner L, Lee JW.

Blood Adv. 2018 Sep 11;2(17):2176-2185. doi: 10.1182/bloodadvances.2018020644.

17.

Eculizumab in pregnancy: a narrative overview.

Sarno L, Tufano A, Maruotti GM, Martinelli P, Balletta MM, Russo D.

J Nephrol. 2018 Aug 29. doi: 10.1007/s40620-018-0517-z. [Epub ahead of print] Review.

PMID:
30159857
18.

Eculizumab application during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: A case report with review of the literature.

Lauritsch-Hernandez LS, Kraehenmann F, Balabanov S, Kimmich N.

Clin Case Rep. 2018 Jun 27;6(8):1582-1587. doi: 10.1002/ccr3.1634. eCollection 2018 Aug.

19.

Eculizumab Bridging before Bone Marrow Transplant for Marrow Failure Disorders Is Safe and Does Not Limit Engraftment.

DeZern AE, Jones RJ, Brodsky RA.

Biol Blood Marrow Transplant. 2018 Dec;24(12):e26-e30. doi: 10.1016/j.bbmt.2018.07.032. Epub 2018 Jul 26.

PMID:
30055352
20.

Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria.

Mastellos DC, Reis ES, Yancopoulou D, Risitano AM, Lambris JD.

Semin Hematol. 2018 Jul;55(3):167-175. doi: 10.1053/j.seminhematol.2018.02.002. Epub 2018 Feb 14. Review.

PMID:
30032754

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