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Items: 19

1.

Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association.

Connelly KE, Weaver TM, Alpsoy A, Gu BX, Musselman CA, Dykhuizen EC.

Nucleic Acids Res. 2018 Dec 29. doi: 10.1093/nar/gky1290. [Epub ahead of print]

PMID:
30597065
2.

The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability.

Torres-Zelada EF, Stephenson RE, Alpsoy A, Anderson BD, Swanson SK, Florens L, Dykhuizen EC, Washburn MP, Weake VM.

J Cell Sci. 2018 Dec 17. pii: jcs.214072. doi: 10.1242/jcs.214072. [Epub ahead of print]

PMID:
30559249
3.

Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.

Marian CA, Stoszko M, Wang L, Leighty MW, de Crignis E, Maschinot CA, Gatchalian J, Carter BC, Chowdhury B, Hargreaves DC, Duvall JR, Crabtree GR, Mahmoudi T, Dykhuizen EC.

Cell Chem Biol. 2018 Dec 20;25(12):1443-1455.e14. doi: 10.1016/j.chembiol.2018.08.004. Epub 2018 Sep 6.

PMID:
30197195
4.

A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.

Soto-Velasquez M, Hayes MP, Alpsoy A, Dykhuizen EC, Watts VJ.

Mol Pharmacol. 2018 Sep;94(3):963-972. doi: 10.1124/mol.118.111849. Epub 2018 Jun 27.

PMID:
29950405
5.

Analysis of Human Nuclear Protein Complexes by Quantitative Mass Spectrometry Profiling.

Connelly KE, Hedrick V, Paschoal Sobreira TJ, Dykhuizen EC, Aryal UK.

Proteomics. 2018 Jun;18(11):e1700427. doi: 10.1002/pmic.201700427. Epub 2018 May 4.

PMID:
29655301
6.

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

Alpsoy A, Dykhuizen EC.

J Biol Chem. 2018 Mar 16;293(11):3892-3903. doi: 10.1074/jbc.RA117.001065. Epub 2018 Jan 26.

PMID:
29374058
7.

Robustness of In Vitro Selection Assays of DNA-Encoded Peptidomimetic Ligands to CBX7 and CBX8.

Denton KE, Wang S, Gignac MC, Milosevich N, Hof F, Dykhuizen EC, Krusemark CJ.

SLAS Discov. 2018 Jun;23(5):417-428. doi: 10.1177/2472555217750871. Epub 2018 Jan 8.

PMID:
29309209
8.

Sequential Salt Extractions for the Analysis of Bulk Chromatin Binding Properties of Chromatin Modifying Complexes.

Porter EG, Connelly KE, Dykhuizen EC.

J Vis Exp. 2017 Oct 2;(128). doi: 10.3791/55369.

9.

Individual Bromodomains of Polybromo-1 Contribute to Chromatin Association and Tumor Suppression in Clear Cell Renal Carcinoma.

Porter EG, Dykhuizen EC.

J Biol Chem. 2017 Feb 17;292(7):2601-2610. doi: 10.1074/jbc.M116.746875. Epub 2017 Jan 4.

10.

CBX Chromodomain Inhibition Enhances Chemotherapy Response in Glioblastoma Multiforme.

Connelly KE, Martin EC, Dykhuizen EC.

Yale J Biol Med. 2016 Dec 23;89(4):431-440. eCollection 2016 Dec.

11.

Compositional and functional diversity of canonical PRC1 complexes in mammals.

Connelly KE, Dykhuizen EC.

Biochim Biophys Acta Gene Regul Mech. 2017 Feb;1860(2):233-245. doi: 10.1016/j.bbagrm.2016.12.006. Epub 2016 Dec 20. Review.

PMID:
28007606
12.

PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma.

Chowdhury B, Porter EG, Stewart JC, Ferreira CR, Schipma MJ, Dykhuizen EC.

PLoS One. 2016 Apr 21;11(4):e0153718. doi: 10.1371/journal.pone.0153718. eCollection 2016.

13.

Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal.

Stoszko M, De Crignis E, Rokx C, Khalid MM, Lungu C, Palstra RJ, Kan TW, Boucher C, Verbon A, Dykhuizen EC, Mahmoudi T.

EBioMedicine. 2015 Nov 27;3:108-121. doi: 10.1016/j.ebiom.2015.11.047. eCollection 2016 Jan.

14.

BAF complexes facilitate decatenation of DNA by topoisomerase II╬▒.

Dykhuizen EC, Hargreaves DC, Miller EL, Cui K, Korshunov A, Kool M, Pfister S, Cho YJ, Zhao K, Crabtree GR.

Nature. 2013 May 30;497(7451):624-7. doi: 10.1038/nature12146. Epub 2013 May 22.

15.

Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation.

Dykhuizen EC, Carmody LC, Tolliday N, Crabtree GR, Palmer MA.

J Biomol Screen. 2012 Oct;17(9):1221-30. Epub 2012 Aug 1.

16.

Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.

Dykhuizen EC, Kiessling LL.

Org Lett. 2009 Jan 1;11(1):193-6. doi: 10.1021/ol802094p.

17.

Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth.

Dykhuizen EC, May JF, Tongpenyai A, Kiessling LL.

J Am Chem Soc. 2008 May 28;130(21):6706-7. doi: 10.1021/ja8018687. Epub 2008 May 1.

PMID:
18447352
18.

Selective tumor cell targeting using low-affinity, multivalent interactions.

Carlson CB, Mowery P, Owen RM, Dykhuizen EC, Kiessling LL.

ACS Chem Biol. 2007 Feb 20;2(2):119-27. Epub 2007 Feb 26.

PMID:
17291050
19.

Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and atrocytes that express CRH-R1.

Stevens SL, Shaw TE, Dykhuizen E, Lessov NS, Hill JK, Wurst W, Stenzel-Poore MP.

J Cereb Blood Flow Metab. 2003 Oct;23(10):1151-9.

PMID:
14526225

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