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Items: 1 to 20 of 40


Cardiac-specific inducible overexpression of human plasma membrane Ca2+ ATPase 4b is cardioprotective and improves survival in mice following ischemic injury.

Sadi AM, Afroze T, Siraj MA, Momen A, White-Dzuro C, Zarrin-Khat D, Handa S, Ban K, Kabir MG, Trivieri MG, Gros R, Backx P, Husain M.

Clin Sci (Lond). 2018 Mar 26;132(6):641-654. doi: 10.1042/CS20171337. Print 2018 Mar 30.


Stat5-dependent cardioprotection in late remote ischaemia preconditioning.

Chen H, Jing XY, Shen YJ, Wang TL, Ou C, Lu SF, Cai Y, Li Q, Chen X, Ding YJ, Yu XC, Zhu BM.

Cardiovasc Res. 2018 Apr 1;114(5):679-689. doi: 10.1093/cvr/cvy014.


Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice.

Merentie M, Rissanen R, Lottonen-Raikaslehto L, Huusko J, Gurzeler E, Turunen MP, Holappa L, Mäkinen P, Ylä-Herttuala S.

PLoS One. 2018 Jan 19;13(1):e0190981. doi: 10.1371/journal.pone.0190981. eCollection 2018.


Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury.

Cortes AL, Gonsalez SR, Rioja LS, Oliveira SSC, Santos ALS, Prieto MC, Melo PA, Lara LS.

Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):102-114. doi: 10.1016/j.bbadis.2017.10.005. Epub 2017 Oct 5.


L-NAME improves doxycycline and ML-7 cardioprotection from oxidative stress.

Bil-Lula I, Krzywonos-Zawadzka A, Sawicka J, Bialy D, Wawrzynska M, Wozniak M, Sawicki G.

Front Biosci (Landmark Ed). 2018 Jan 1;23:298-309.


Early changes of left ventricular filling pattern after reperfused ST-elevation myocardial infarction and doxycycline therapy: Insights from the TIPTOP trial.

Cerisano G, Buonamici P, Parodi G, Santini A, Moschi G, Valenti R, Migliorini A, Colonna P, Bellandi B, Gori AM, Antoniucci D.

Int J Cardiol. 2017 Aug 1;240:43-48. doi: 10.1016/j.ijcard.2017.03.125. Epub 2017 Apr 7.


In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia.

Seo JH, Lee MY, Yu JH, Kim MS, Song M, Seo CH, Kim HH, Cho SR.

Mol Ther. 2016 Sep;24(9):1538-49. doi: 10.1038/mt.2016.124. Epub 2016 Jun 22.


Subthreshold nitric oxide synthase inhibition improves synergistic effects of subthreshold MMP-2/MLCK-mediated cardiomyocyte protection from hypoxic injury.

Bil-Lula I, Lin HB, Biały D, Wawrzyńska M, Diebel L, Sawicka J, Woźniak M, Sawicki G.

J Cell Mol Med. 2016 Jun;20(6):1086-94. doi: 10.1111/jcmm.12827. Epub 2016 Mar 17.


Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury.

Szczepanek K, Allegood J, Aluri H, Hu Y, Chen Q, Lesnefsky EJ.

Biochim Biophys Acta. 2016 Apr;1861(4):294-300. doi: 10.1016/j.bbalip.2015.12.004. Epub 2015 Dec 12.


Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling.

Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub P, Villarreal F, Ceballos G.

Eur J Pharmacol. 2014 Dec 5;744:76-82. doi: 10.1016/j.ejphar.2014.09.042. Epub 2014 Oct 2.


Myocardial matrix metalloproteinase-2: inside out and upside down.

DeCoux A, Lindsey ML, Villarreal F, Garcia RA, Schulz R.

J Mol Cell Cardiol. 2014 Dec;77:64-72. doi: 10.1016/j.yjmcc.2014.09.016. Epub 2014 Sep 28. Review.


Dystrophin proteolysis: a potential target for MMP-2 and its prevention by ischemic preconditioning.

Buchholz B, Perez V, Siachoque N, Miksztowicz V, Berg G, Rodríguez M, Donato M, Gelpi RJ.

Am J Physiol Heart Circ Physiol. 2014 Jul 1;307(1):H88-96. doi: 10.1152/ajpheart.00242.2013. Epub 2014 May 2.


Activation of α1B-adrenoceptors contributes to intermittent hypobaric hypoxia-improved postischemic myocardial performance via inhibiting MMP-2 activation.

Gao L, Chen L, Lu ZZ, Gao H, Wu L, Chen YX, Zhang CM, Jiang YK, Jing Q, Zhang YY, Yang HT.

Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1569-81. doi: 10.1152/ajpheart.00772.2013. Epub 2014 Apr 4.


Induced overexpression of phospholemman S68E mutant improves cardiac contractility and mortality after ischemia-reperfusion.

Wang J, Song J, Gao E, Zhang XQ, Gu T, Yu D, Koch WJ, Feldman AM, Cheung JY.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1066-77. doi: 10.1152/ajpheart.00861.2013. Epub 2014 Jan 31.


Effect of metalloproteinase inhibitor on early postinfarction remodeling in the most acute phase of myocardial infarction.

Kryzhanovskii SA, Ionova EO, Stolyaruk VN, Tsorin IB, Vititnova MB.

Bull Exp Biol Med. 2013 Nov;156(1):19-24.


Improvement of functional recovery of donor heart following cold static storage with doxycycline cardioplegia.

Ozcinar E, Okatan EN, Tuncay E, Eryilmaz S, Turan B.

Cardiovasc Toxicol. 2014 Mar;14(1):64-73. doi: 10.1007/s12012-013-9231-1.


Early short-term doxycycline therapy in patients with acute myocardial infarction and left ventricular dysfunction to prevent the ominous progression to adverse remodelling: the TIPTOP trial.

Cerisano G, Buonamici P, Valenti R, Sciagrà R, Raspanti S, Santini A, Carrabba N, Dovellini EV, Romito R, Pupi A, Colonna P, Antoniucci D.

Eur Heart J. 2014 Jan;35(3):184-91. doi: 10.1093/eurheartj/eht420. Epub 2013 Oct 8.


Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass.

Schulze CJ, Castro MM, Kandasamy AD, Cena J, Bryden C, Wang SH, Koshal A, Tsuyuki RT, Finegan BA, Schulz R.

Crit Care Med. 2013 Nov;41(11):2512-20. doi: 10.1097/CCM.0b013e318292373c.


HIF-1α in heart: protective mechanisms.

Wu J, Chen P, Li Y, Ardell C, Der T, Shohet R, Chen M, Wright GL.

Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H821-8. doi: 10.1152/ajpheart.00140.2013. Epub 2013 Jul 19.


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