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Items: 1 to 20 of 52

1.

Broadening the impact of immunotherapy to pancreatic cancer: Challenges and opportunities.

Balachandran VP, Beatty GL, Dougan SK.

Gastroenterology. 2019 Jan 17. pii: S0016-5085(19)30054-X. doi: 10.1053/j.gastro.2018.12.038. [Epub ahead of print]

PMID:
30660727
2.

Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell-Effector Responses.

Clancy-Thompson E, Devlin CA, Tyler PM, Servos MM, Ali LR, Ventre KS, Bhuiyan MA, Bruck PT, Birnbaum ME, Dougan SK.

Cancer Immunol Res. 2018 Dec;6(12):1524-1536. doi: 10.1158/2326-6066.CIR-18-0348. Epub 2018 Oct 23.

PMID:
30352798
3.

Radiation and Local Anti-CD40 Generate an Effective in situ Vaccine in Preclinical Models of Pancreatic Cancer.

Yasmin-Karim S, Bruck PT, Moreau M, Kunjachan S, Chen GZ, Kumar R, Grabow S, Dougan SK, Ngwa W.

Front Immunol. 2018 Sep 7;9:2030. doi: 10.3389/fimmu.2018.02030. eCollection 2018.

4.

Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity.

Ito Y, Ashenberg O, Pyrdol J, Luoma AM, Rozenblatt-Rosen O, Hofree M, Christian E, Ferrari de Andrade L, Tay RE, Teyton L, Regev A, Dougan SK, Wucherpfennig KW.

J Exp Med. 2018 Oct 1;215(10):2617-2635. doi: 10.1084/jem.20180300. Epub 2018 Sep 5.

PMID:
30185635
5.

One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice.

Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD.

EMBO J. 2018 Sep 14;37(18). pii: e99243. doi: 10.15252/embj.201899243. Epub 2018 Aug 7.

6.

Unmasking Pancreatic Cancer: Epitope Spreading After Single Antigen Chimeric Antigen Receptor T-Cell Therapy in a Human Phase I Trial.

Heckler M, Dougan SK.

Gastroenterology. 2018 Jul;155(1):11-14. doi: 10.1053/j.gastro.2018.06.023. Epub 2018 Jun 6. No abstract available.

PMID:
29885301
7.

Regulation of innate and adaptive antitumor immunity by IAP antagonists.

Dougan SK, Dougan M.

Immunotherapy. 2018 Jul;10(9):787-796. doi: 10.2217/imt-2017-0185. Epub 2018 May 29.

8.

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy.

Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaan3464. doi: 10.1126/scitranslmed.aan3464.

PMID:
29643230
9.

Anti-CTLA-4 therapy requires an Fc domain for efficacy.

Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3912-3917. doi: 10.1073/pnas.1801524115. Epub 2018 Mar 26.

10.

Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs.

Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK.

Cancer Immunol Res. 2018 Apr;6(4):389-401. doi: 10.1158/2326-6066.CIR-17-0495. Epub 2018 Feb 19.

PMID:
29459478
11.

Generation of Ca2+-independent sortase A mutants with enhanced activity for protein and cell surface labeling.

Jeong HJ, Abhiraman GC, Story CM, Ingram JR, Dougan SK.

PLoS One. 2017 Dec 4;12(12):e0189068. doi: 10.1371/journal.pone.0189068. eCollection 2017.

12.

The Pancreatic Cancer Microenvironment.

Dougan SK.

Cancer J. 2017 Nov/Dec;23(6):321-325. doi: 10.1097/PPO.0000000000000288. Review.

PMID:
29189327
13.

IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells.

Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK.

Cancer Immunol Res. 2018 Jan;6(1):25-35. doi: 10.1158/2326-6066.CIR-17-0490. Epub 2017 Nov 29.

14.

PD-L1 is an activation-independent marker of brown adipocytes.

Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL.

Nat Commun. 2017 Sep 21;8(1):647. doi: 10.1038/s41467-017-00799-8.

15.

CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation.

Zeissig S, Peuker K, Iyer S, Gensollen T, Dougan SK, Olszak T, Kaser A, Blumberg RS.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10449-10454. doi: 10.1073/pnas.1701428114. Epub 2017 Sep 11.

16.

Localized CD47 blockade enhances immunotherapy for murine melanoma.

Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10184-10189. doi: 10.1073/pnas.1710776114. Epub 2017 Sep 5.

17.

Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor.

Bilate AM, Bousbaine D, Mesin L, Agudelo M, Leube J, Kratzert A, Dougan SK, Victora GD, Ploegh HL.

Sci Immunol. 2016 Aug 26;1(2):eaaf7471. doi: 10.1126/sciimmunol.aaf7471. Epub 2016 Aug 26.

18.

Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets.

Clancy-Thompson E, Chen GZ, Tyler PM, Servos MM, Barisa M, Brennan PJ, Ploegh HL, Dougan SK.

J Immunol. 2017 Jul 1;199(1):159-171. doi: 10.4049/jimmunol.1700214. Epub 2017 Jun 2.

19.

Targeting Immunotherapy to the Tumor Microenvironment.

Dougan M, Dougan SK.

J Cell Biochem. 2017 Oct;118(10):3049-3054. doi: 10.1002/jcb.26005. Epub 2017 May 15. Review.

PMID:
28332219
20.

Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.

Pishesha N, Bilate AM, Wibowo MC, Huang NJ, Li Z, Deshycka R, Bousbaine D, Li H, Patterson HC, Dougan SK, Maruyama T, Lodish HF, Ploegh HL.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3157-3162. doi: 10.1073/pnas.1701746114. Epub 2017 Mar 7. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 25;114(17 ):E3583. Dhesycka, Rhogerry [corrected to Deshycka, Rhogerry].

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