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Items: 1 to 20 of 42


Neuroinflammation in neurodegeneration: role in pathophysiology, therapeutic opportunities and clinical perspectives.

Dorothée G.

J Neural Transm (Vienna). 2018 May;125(5):749-750. doi: 10.1007/s00702-018-1880-6. No abstract available.


Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease.

Hamelin L, Lagarde J, Dorothée G, Potier MC, Corlier F, Kuhnast B, Caillé F, Dubois B, Fillon L, Chupin M, Bottlaender M, Sarazin M.

Brain. 2018 Jun 1;141(6):1855-1870. doi: 10.1093/brain/awy079.


Neutrophil hyperactivation correlates with Alzheimer's disease progression.

Dong Y, Lagarde J, Xicota L, Corne H, Chantran Y, Chaigneau T, Crestani B, Bottlaender M, Potier MC, Aucouturier P, Dorothée G, Sarazin M, Elbim C.

Ann Neurol. 2018 Feb;83(2):387-405. doi: 10.1002/ana.25159.


[Tau and cognitive disorders: a role for T lymphocytes].

Laurent C, Dorothée G, Hunot S, Martin E, Delarasse C, Buée L, Blum D.

Med Sci (Paris). 2017 Oct;33(10):817-819. doi: 10.1051/medsci/20173310002. Epub 2017 Oct 10. French. No abstract available.


Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology.

Dansokho C, Aucouturier P, Dorothée G.

Brain. 2017 Jul 1;140(7):e39. doi: 10.1093/brain/awx108. No abstract available.


Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy.

Laurent C, Dorothée G, Hunot S, Martin E, Monnet Y, Duchamp M, Dong Y, Légeron FP, Leboucher A, Burnouf S, Faivre E, Carvalho K, Caillierez R, Zommer N, Demeyer D, Jouy N, Sazdovitch V, Schraen-Maschke S, Delarasse C, Buée L, Blum D.

Brain. 2017 Jan;140(1):184-200. doi: 10.1093/brain/aww270. Epub 2016 Nov 5.


NOV/CCN3: A New Adipocytokine Involved in Obesity-Associated Insulin Resistance.

Martinerie C, Garcia M, Do TT, Antoine B, Moldes M, Dorothee G, Kazazian C, Auclair M, Buyse M, Ledent T, Marchal PO, Fesatidou M, Beisseiche A, Koseki H, Hiraoka S, Chadjichristos CE, Blondeau B, Denis RG, Luquet S, Fève B.

Diabetes. 2016 Sep;65(9):2502-15. doi: 10.2337/db15-0617. Epub 2016 Jun 9.


Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.

Meijer L, Nelson DJ, Riazanski V, Gabdoulkhakova AG, Hery-Arnaud G, Le Berre R, Loaëc N, Oumata N, Galons H, Nowak E, Gueganton L, Dorothée G, Prochazkova M, Hall B, Kulkarni AB, Gray RD, Rossi AG, Witko-Sarsat V, Norez C, Becq F, Ravel D, Mottier D, Rault G.

J Innate Immun. 2016;8(4):330-49. doi: 10.1159/000444256. Epub 2016 Mar 18. Review.


Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging.

Hamelin L, Lagarde J, Dorothée G, Leroy C, Labit M, Comley RA, de Souza LC, Corne H, Dauphinot L, Bertoux M, Dubois B, Gervais P, Colliot O, Potier MC, Bottlaender M, Sarazin M; Clinical IMABio3 team.

Brain. 2016 Apr;139(Pt 4):1252-64. doi: 10.1093/brain/aww017. Epub 2016 Mar 15.


Regulatory T cells delay disease progression in Alzheimer-like pathology.

Dansokho C, Ait Ahmed D, Aid S, Toly-Ndour C, Chaigneau T, Calle V, Cagnard N, Holzenberger M, Piaggio E, Aucouturier P, Dorothée G.

Brain. 2016 Apr;139(Pt 4):1237-51. doi: 10.1093/brain/awv408. Epub 2016 Feb 1.


Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer's disease patients.

Corlier F, Rivals I, Lagarde J, Hamelin L, Corne H, Dauphinot L, Ando K, Cossec JC, Fontaine G, Dorothée G, Malaplate-Armand C, Olivier JL, Dubois B, Bottlaender M, Duyckaerts C, Sarazin M, Potier MC; Clinical ImaBio3 Team.

Transl Psychiatry. 2015 Jul 7;5:e595. doi: 10.1038/tp.2015.87.


Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer's disease.

Rosset MB, Lui G, Dansokho C, Chaigneau T, Dorothée G.

J Neuroinflammation. 2015 May 16;12:95. doi: 10.1186/s12974-015-0317-5.


Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype.

Ferrand N, Gnanapragasam A, Dorothee G, Redeuilh G, Larsen AK, Sabbah M.

PLoS One. 2014 Feb 3;9(2):e87878. doi: 10.1371/journal.pone.0087878. eCollection 2014.


Disease-specific adaptive immune biomarkers in Alzheimer's disease and related pathologies.

Dorothée G, Sarazin M, Aucouturier P.

Rev Neurol (Paris). 2013 Oct;169(10):715-8. doi: 10.1016/j.neurol.2013.07.023. Epub 2013 Sep 6. Review.


Plasma Anti-Amyloid-β Autoantibodies in All Alzheimer Disease Types-Reply.

Dorothée G, de Souza LC, Sarazin M, Aucouturier P.

Arch Neurol. 2012 Nov 1;69(11):1525-7. doi: 10.1001/archneurol.2012.2779. No abstract available.


Immunotherapy in Alzheimer's disease: do we have all the pieces of the puzzle?

Sarazin M, Dorothée G, de Souza LC, Aucouturier P.

Biol Psychiatry. 2013 Sep 1;74(5):329-32. doi: 10.1016/j.biopsych.2013.04.011. Epub 2013 May 14. Review.


Distinct patterns of antiamyloid-β antibodies in typical and atypical Alzheimer disease.

Dorothée G, Bottlaender M, Moukari E, de Souza LC, Maroy R, Corlier F, Colliot O, Chupin M, Lamari F, Lehéricy S, Dubois B, Sarazin M, Aucouturier P.

Arch Neurol. 2012 Sep;69(9):1181-5. doi: 10.1001/archneurol.2012.604.


[Adaptive immunity to Aβ amyloid peptide in Alzheimer's disease: lessons and perspectives].

Dorothée G, Aucouturier P.

Med Sci (Paris). 2011 Nov;27(11):938-40. doi: 10.1051/medsci/20112711008. Epub 2011 Nov 30. French. No abstract available.


MHC-independent genetic factors control the magnitude of CD4+ T cell responses to amyloid-β peptide in mice through regulatory T cell-mediated inhibition.

Toly-Ndour C, Lui G, Nunes MM, Bruley-Rosset M, Aucouturier P, Dorothée G.

J Immunol. 2011 Nov 1;187(9):4492-500. doi: 10.4049/jimmunol.1003953. Epub 2011 Sep 26.


Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.

Kim HJ, Alonzo ES, Dorothee G, Pollard JW, Sant'Angelo DB.

PLoS One. 2010 Jul 6;5(7):e11439. doi: 10.1371/journal.pone.0011439.

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