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Items: 1 to 20 of 31

1.

3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.

Tian X, Liu K, Zu X, Ma F, Li Z, Lee M, Chen H, Li Y, Zhao Y, Liu F, Oi N, Bode AM, Dong Z, Kim DJ.

Cancer Lett. 2019 Apr 28;448:20-30. doi: 10.1016/j.canlet.2019.01.031. Epub 2019 Feb 1.

PMID:
30716361
2.

[Treatment with anti-cancer agents results in profound changes in lncRNA expression in colon cancer cells].

Zinovieva OL, Grineva EN, Prokofjeva MM, Karpov DS, Krasnov GS, Prassolov VS, Mashkova TD, Lisitsyn NA.

Mol Biol (Mosk). 2017 Sep-Oct;51(5):841-848. doi: 10.7868/S0026898417050123. Russian.

3.

Enhancing miR-132 expression by aryl hydrocarbon receptor attenuates tumorigenesis associated with chronic colitis.

Alzahrani AM, Hanieh H, Ibrahim HM, Mohafez O, Shehata T, Bani Ismail M, Alfwuaires M.

Int Immunopharmacol. 2017 Nov;52:342-351. doi: 10.1016/j.intimp.2017.09.015. Epub 2017 Oct 7.

4.

Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor.

Popolo A, Pinto A, Daglia M, Nabavi SF, Farooqi AA, Rastrelli L.

Semin Cancer Biol. 2017 Oct;46:132-137. doi: 10.1016/j.semcancer.2017.06.002. Epub 2017 Jun 13. Review.

PMID:
28596013
5.

Therapeutic Potential of Targeting Wnt/β-Catenin Pathway in Treatment of Colorectal Cancer: Rational and Progress.

Bahrami A, Amerizadeh F, ShahidSales S, Khazaei M, Ghayour-Mobarhan M, Sadeghnia HR, Maftouh M, Hassanian SM, Avan A.

J Cell Biochem. 2017 Aug;118(8):1979-1983. doi: 10.1002/jcb.25903. Epub 2017 Apr 25. Review.

PMID:
28109136
6.

The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation.

Faust D, Nikolova T, Wätjen W, Kaina B, Dietrich C.

Arch Toxicol. 2017 Feb;91(2):967-982. doi: 10.1007/s00204-016-1672-4. Epub 2016 Feb 8.

PMID:
26856715
7.

The estrogenic effect of trigonelline and 3,3-diindolymethane on cell growth in non-malignant colonocytes.

Yoo G, Allred CD.

Food Chem Toxicol. 2016 Jan;87:23-30. doi: 10.1016/j.fct.2015.11.015. Epub 2015 Nov 25.

PMID:
26593444
8.

Sulindac, 3,3'-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis.

Femia AP, Soares PV, Luceri C, Lodovici M, Giannini A, Caderni G.

BMC Cancer. 2015 Sep 3;15:611. doi: 10.1186/s12885-015-1627-9.

9.

Genome-wide transcriptome analysis reveals inactivation of Wnt/β-catenin by 3,3'-diindolylmethane inhibiting proliferation of colon cancer cells.

Leem SH, Li XJ, Park MH, Park BH, Kim SM.

Int J Oncol. 2015 Sep;47(3):918-26. doi: 10.3892/ijo.2015.3089. Epub 2015 Jul 17.

PMID:
26203047
10.

3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation.

Fadlalla K, Elgendy R, Gilbreath E, Pondugula SR, Yehualaeshet T, Mansour M, Serbessa T, Manne U, Samuel T.

Oncol Rep. 2015 Jul;34(1):495-503. doi: 10.3892/or.2015.3970. Epub 2015 May 11.

11.

Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.

Lee SO, Li X, Hedrick E, Jin UH, Tjalkens RB, Backos DS, Li L, Zhang Y, Wu Q, Safe S.

Mol Endocrinol. 2014 Oct;28(10):1729-39. doi: 10.1210/me.2014-1102. Epub 2014 Aug 6.

12.

Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells.

Li XJ, Leem SH, Park MH, Kim SM.

Int J Oncol. 2013 Dec;43(6):1992-8. doi: 10.3892/ijo.2013.2121. Epub 2013 Oct 3.

PMID:
24100865
13.

Structural elaboration of a natural product: identification of 3,3'-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents.

Kandekar S, Preet R, Kashyap M, Renu Prasad MU, Mohapatra P, Das D, Satapathy SR, Siddharth S, Jain V, Choudhuri M, Kundu CN, Guchhait SK, Bharatam PV.

ChemMedChem. 2013 Nov;8(11):1873-84. doi: 10.1002/cmdc.201300273. Epub 2013 Aug 28.

PMID:
23983049
14.

The indolic diet-derivative, 3,3'-diindolylmethane, induced apoptosis in human colon cancer cells through upregulation of NDRG1.

Lerner A, Grafi-Cohen M, Napso T, Azzam N, Fares F.

J Biomed Biotechnol. 2012;2012:256178. doi: 10.1155/2012/256178. Epub 2011 Nov 13.

15.

Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.

Li Y, Li X, Guo B.

Cancer Res. 2010 Jan 15;70(2):646-54. doi: 10.1158/0008-5472.CAN-09-1924. Epub 2010 Jan 12.

16.

The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells.

Choi KH, Kim HK, Kim JH, Choi ES, Shin JA, Lee SO, Chintharlapalli S, Safe S, Abdelrahim M, Kong G, Choi HS, Jung JY, Cho HT, Cho NP, Cho SD.

Eur J Cancer Prev. 2010 Mar;19(2):153-9. doi: 10.1097/CEJ.0b013e328333d088.

PMID:
19949342
18.

Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.

Choi HJ, Lim DY, Park JH.

BMC Gastroenterol. 2009 May 29;9:39. doi: 10.1186/1471-230X-9-39.

19.

3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.

Bhatnagar N, Li X, Chen Y, Zhou X, Garrett SH, Guo B.

Cancer Prev Res (Phila). 2009 Jun;2(6):581-9. doi: 10.1158/1940-6207.CAPR-08-0142. Epub 2009 May 26.

20.

3,3'-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice.

Kim YH, Kwon HS, Kim DH, Shin EK, Kang YH, Park JH, Shin HK, Kim JK.

Inflamm Bowel Dis. 2009 Aug;15(8):1164-73. doi: 10.1002/ibd.20917.

PMID:
19334074

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