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Items: 13

1.

3,3'-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis.

Luo Q, Yang A, Cao Q, Guan H.

BMC Pharmacol Toxicol. 2018 Nov 9;19(1):71. doi: 10.1186/s40360-018-0262-x.

2.

Molecular Simulation Studies of 3,3'-Diindolylmethane as a Potent MicroRNA-21 Antagonist.

Junaid M, Dash R, Islam N, Chowdhury J, Alam MJ, Nath SD, Shakil MAS, Azam A, Quader SM, Zahid Hosen SM.

J Pharm Bioallied Sci. 2017 Oct-Dec;9(4):259-265. doi: 10.4103/jpbs.JPBS_266_16.

3.

3,3'‑Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells.

Liang K, Qian WH, Zong J.

Mol Med Rep. 2017 Dec;16(6):9553-9560. doi: 10.3892/mmr.2017.7788. Epub 2017 Oct 13.

PMID:
29039568
4.

Attenuation of doxorubicin-induced cardiotoxicity and genotoxicity by an indole-based natural compound 3,3'-diindolylmethane (DIM) through activation of Nrf2/ARE signaling pathways and inhibiting apoptosis.

Hajra S, Basu A, Singha Roy S, Patra AR, Bhattacharya S.

Free Radic Res. 2017 Oct;51(9-10):812-827. doi: 10.1080/10715762.2017.1381694. Epub 2017 Oct 12.

PMID:
28922986
5.

MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells.

Ito K, Eguchi Y, Imagawa Y, Akai S, Mochizuki H, Tsujimoto Y.

Cell Death Discov. 2017 Feb 27;3:17013. doi: 10.1038/cddiscovery.2017.13. eCollection 2017.

6.

Indole-3-Carbinol and Its Role in Chronic Diseases.

Licznerska B, Baer-Dubowska W.

Adv Exp Med Biol. 2016;928:131-154. Review.

PMID:
27671815
7.

DIM attenuates TGF-β1-induced myofibroblast differentiation in neonatal rat cardiac fibroblasts.

Li J, Zhang W, Jiao R, Yang Z, Yuan Y, Wu Q, Hu Z, Xiang S, Tang Q.

Int J Clin Exp Pathol. 2015 May 1;8(5):5121-8. eCollection 2015.

8.

3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α.

Zong J, Wu QQ, Zhou H, Zhang JY, Yuan Y, Bian ZY, Deng W, Dai J, Li FF, Xu M, Fang Y, Tang QZ.

Mol Med Rep. 2015 Jul;12(1):1247-52. doi: 10.3892/mmr.2015.3523. Epub 2015 Mar 20.

PMID:
25816057
9.

3,3'-Diindolylmethane improves myocardial energy metabolism imbalance induced by pressure overload via AMPKα in mice.

Deng W, Zong J, Wei L, Guo H, Cheng Z, Zhang R, Lin Y, Tang Q.

Int J Cardiol. 2014 Nov 15;177(1):235-7. doi: 10.1016/j.ijcard.2014.09.037. Epub 2014 Sep 28. No abstract available.

PMID:
25499385
10.

3,3'-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway.

Yao Z, Hu W, Yin S, Huang Z, Zhu Q, Chen J, Zang Y, Dong L, Zhang J.

Pharmacol Res. 2013 Apr;70(1):139-46. doi: 10.1016/j.phrs.2013.01.006. Epub 2013 Jan 31.

PMID:
23376355
11.

3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.

Guan H, Zhu L, Fu M, Yang D, Tian S, Guo Y, Cui C, Wang L, Jiang H.

PLoS One. 2012;7(4):e34957. doi: 10.1371/journal.pone.0034957. Epub 2012 Apr 10.

12.

3,3'-Diindolylmethane decreases VCAM-1 expression and alleviates experimental colitis via a BRCA1-dependent antioxidant pathway.

Huang Z, Zuo L, Zhang Z, Liu J, Chen J, Dong L, Zhang J.

Free Radic Biol Med. 2011 Jan 15;50(2):228-36. doi: 10.1016/j.freeradbiomed.2010.10.703. Epub 2010 Oct 26.

PMID:
21034812
13.

3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice.

Chang X, Tou JC, Hong C, Kim HA, Riby JE, Firestone GL, Bjeldanes LF.

Carcinogenesis. 2005 Apr;26(4):771-8. Epub 2005 Jan 20.

PMID:
15661811

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