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Items: 1 to 20 of 62


Sex-specific differences in motor unit remodeling in a mouse model of ALS.

Martineau É, Di Polo A, Vande Velde C, Robitaille R.

eNeuro. 2020 Feb 6. pii: ENEURO.0388-19.2020. doi: 10.1523/ENEURO.0388-19.2020. [Epub ahead of print]


Retinal ischemia induces α-SMA-mediated capillary pericyte contraction coincident with perivascular glycogen depletion.

Alarcon-Martinez L, Yilmaz-Ozcan S, Yemisci M, Schallek J, Kılıç K, Villafranca-Baughman D, Can A, Di Polo A, Dalkara T.

Acta Neuropathol Commun. 2019 Aug 20;7(1):134. doi: 10.1186/s40478-019-0761-z.


Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS.

Martineau É, Di Polo A, Vande Velde C, Robitaille R.

Elife. 2018 Oct 15;7. pii: e41973. doi: 10.7554/eLife.41973.


An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous System.

Beckers A, Van Dyck A, Bollaerts I, Van Houcke J, Lefevere E, Andries L, Agostinone J, Van Hove I, Di Polo A, Lemmens K, Moons L.

Mol Neurobiol. 2019 May;56(5):3175-3192. doi: 10.1007/s12035-018-1292-5. Epub 2018 Aug 13.


New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina.

Simpson EM, Korecki AJ, Fornes O, McGill TJ, Cueva-Vargas JL, Agostinone J, Farkas RA, Hickmott JW, Lam SL, Mathelier A, Renner LM, Stoddard J, Zhou M, Di Polo A, Neuringer M, Wasserman WW.

Hum Gene Ther. 2019 Mar;30(3):257-272. doi: 10.1089/hum.2018.118. Epub 2018 Oct 2.


Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury.

Agostinone J, Alarcon-Martinez L, Gamlin C, Yu WQ, Wong ROL, Di Polo A.

Brain. 2018 Jul 1;141(7):1963-1980. doi: 10.1093/brain/awy142.


Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection.

Alarcon-Martinez L, Yilmaz-Ozcan S, Yemisci M, Schallek J, Kılıç K, Can A, Di Polo A, Dalkara T.

Elife. 2018 Mar 21;7. pii: e34861. doi: 10.7554/eLife.34861.


Mitochondrial dynamics, transport, and quality control: A bottleneck for retinal ganglion cell viability in optic neuropathies.

Ito YA, Di Polo A.

Mitochondrion. 2017 Sep;36:186-192. doi: 10.1016/j.mito.2017.08.014. Epub 2017 Sep 1. Review.


Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease.

Chiasseu M, Alarcon-Martinez L, Belforte N, Quintero H, Dotigny F, Destroismaisons L, Vande Velde C, Panayi F, Louis C, Di Polo A.

Mol Neurodegener. 2017 Aug 3;12(1):58. doi: 10.1186/s13024-017-0199-3.


Neuroinflammation in glaucoma: A new opportunity.

Williams PA, Marsh-Armstrong N, Howell GR; Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants.

Exp Eye Res. 2017 Apr;157:20-27. doi: 10.1016/j.exer.2017.02.014. Epub 2017 Feb 24. Review.


Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma.

Chiasseu M, Cueva Vargas JL, Destroismaisons L, Vande Velde C, Leclerc N, Di Polo A.

J Neurosci. 2016 May 25;36(21):5785-98. doi: 10.1523/JNEUROSCI.3986-15.2016.


The glial cell modulator ibudilast attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma through protein kinase A signaling.

Cueva Vargas JL, Belforte N, Di Polo A.

Neurobiol Dis. 2016 Sep;93:156-71. doi: 10.1016/j.nbd.2016.05.002. Epub 2016 May 6.


Neuroinflammation in glaucoma: soluble tumor necrosis factor alpha and the connection with excitotoxic damage.

Vargas JL, Di Polo A.

Neural Regen Res. 2016 Mar;11(3):424-6. doi: 10.4103/1673-5374.179053. No abstract available.


A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice.

Ito YA, Belforte N, Cueva Vargas JL, Di Polo A.

J Vis Exp. 2016 Mar 23;(109):e53731. doi: 10.3791/53731.


Retinal ganglion cell dendrite pathology and synapse loss: Implications for glaucoma.

Agostinone J, Di Polo A.

Prog Brain Res. 2015;220:199-216. doi: 10.1016/bs.pbr.2015.04.012. Epub 2015 Jun 30. Review.


Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation.

Cueva Vargas JL, Osswald IK, Unsain N, Aurousseau MR, Barker PA, Bowie D, Di Polo A.

J Neurosci. 2015 Sep 2;35(35):12088-102. doi: 10.1523/JNEUROSCI.1273-15.2015.


Dendrite pathology and neurodegeneration: focus on mTOR.

Di Polo A.

Neural Regen Res. 2015 Apr;10(4):559-61. doi: 10.4103/1673-5374.155421. No abstract available.


REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury.

Morquette B, Morquette P, Agostinone J, Feinstein E, McKinney RA, Kolta A, Di Polo A.

Cell Death Differ. 2015 Apr;22(4):612-25. doi: 10.1038/cdd.2014.149. Epub 2014 Sep 26.


Development of a cell permeable competitive antagonist of RhoA and CRMP4 binding, TAT-C4RIP, to promote neurite outgrowth.

Khazaei MR, Montcalm S, Di Polo A, Fournier AE, Durocher Y, Ong Tone S.

J Mol Neurosci. 2015 Feb;55(2):406-15.


Drug and gene delivery to the back of the eye: from bench to bedside.

Rowe-Rendleman CL, Durazo SA, Kompella UB, Rittenhouse KD, Di Polo A, Weiner AL, Grossniklaus HE, Naash MI, Lewin AS, Horsager A, Edelhauser HF.

Invest Ophthalmol Vis Sci. 2014 Apr 28;55(4):2714-30. doi: 10.1167/iovs.13-13707. Review. No abstract available.

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