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Items: 1 to 20 of 38

1.

Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells.

Hwang S, Gustafsson HT, O'Sullivan C, Bisceglia G, Huang X, Klose C, Schevchenko A, Dickson RC, Cavaliere P, Dephoure N, Torres EM.

Cell Rep. 2017 Dec 26;21(13):3807-3818. doi: 10.1016/j.celrep.2017.11.103.

2.

Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.

Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, Blackwell TK, Yu JJ, Rabinowitz JD, Cantley LC, Blenis J.

Cell. 2017 Dec 14;171(7):1545-1558.e18. doi: 10.1016/j.cell.2017.10.037. Epub 2017 Nov 16.

PMID:
29153836
3.

A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast.

Clarke J, Dephoure N, Horecka I, Gygi S, Kellogg D.

Mol Biol Cell. 2017 Oct 1;28(20):2589-2599. doi: 10.1091/mbc.E17-01-0081. Epub 2017 Aug 9.

4.

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.

Yoon SO, Shin S, Karreth FA, Buel GR, Jedrychowski MP, Plas DR, Dedhar S, Gygi SP, Roux PP, Dephoure N, Blenis J.

Mol Cell. 2017 Aug 3;67(3):512-527.e4. doi: 10.1016/j.molcel.2017.06.033. Epub 2017 Jul 27.

5.

Deep Coverage of Global Protein Expression and Phosphorylation in Breast Tumor Cell Lines Using TMT 10-plex Isobaric Labeling.

Huang FK, Zhang G, Lawlor K, Nazarian A, Philip J, Tempst P, Dephoure N, Neubert TA.

J Proteome Res. 2017 Mar 3;16(3):1121-1132. doi: 10.1021/acs.jproteome.6b00374. Epub 2017 Feb 3.

6.

Protein Kinase C Controls Binding of Igo/ENSA Proteins to Protein Phosphatase 2A in Budding Yeast.

Thai V, Dephoure N, Weiss A, Ferguson J, Leitao R, Gygi SP, Kellogg DR.

J Biol Chem. 2017 Mar 24;292(12):4925-4941. doi: 10.1074/jbc.M116.753004. Epub 2017 Jan 18.

7.

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation.

Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, Dephoure N, Satterstrom FK, Sheffer M, Spinelli JB, Gygi S, Rabinowitz JD, Sharpe AH, Haigis MC.

Cell Metab. 2016 Jul 12;24(1):104-17. doi: 10.1016/j.cmet.2016.06.007.

8.

Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks.

Zhou C, Elia AE, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3667-75. doi: 10.1073/pnas.1602827113. Epub 2016 Jun 13.

9.

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.

Mol Cell. 2015 Sep 3;59(5):867-81. doi: 10.1016/j.molcel.2015.05.006. Epub 2015 Jun 4.

10.

Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly.

Lucena R, Dephoure N, Gygi SP, Kellogg DR, Tallada VA, Daga RR, Jimenez J.

J Cell Biol. 2015 May 11;209(3):387-402. doi: 10.1083/jcb.201412144.

11.

Proteomic Profiling of Paclitaxel Treated Cells Identifies a Novel Mechanism of Drug Resistance Mediated by PDCD4.

Xu H, Dephoure N, Sun H, Zhang H, Fan F, Liu J, Ning X, Dai S, Liu B, Gao M, Fu S, Gygi SP, Zhou C.

J Proteome Res. 2015 Jun 5;14(6):2480-91. doi: 10.1021/acs.jproteome.5b00004. Epub 2015 May 14.

PMID:
25928036
12.

Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.

Dephoure N, Hwang S, O'Sullivan C, Dodgson SE, Gygi SP, Amon A, Torres EM.

Elife. 2014 Jul 29;3:e03023. doi: 10.7554/eLife.03023.

13.

SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration.

Van Vranken JG, Bricker DK, Dephoure N, Gygi SP, Cox JE, Thummel CS, Rutter J.

Cell Metab. 2014 Aug 5;20(2):241-52. doi: 10.1016/j.cmet.2014.05.012. Epub 2014 Jun 19.

14.

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins.

Chen YC, Umanah GK, Dephoure N, Andrabi SA, Gygi SP, Dawson TM, Dawson VL, Rutter J.

EMBO J. 2014 Jul 17;33(14):1548-64. doi: 10.15252/embj.201487943. Epub 2014 May 19.

15.

PP2ARts1 is a master regulator of pathways that control cell size.

Zapata J, Dephoure N, Macdonough T, Yu Y, Parnell EJ, Mooring M, Gygi SP, Stillman DJ, Kellogg DR.

J Cell Biol. 2014 Feb 3;204(3):359-76. doi: 10.1083/jcb.201309119.

16.

The Hippo signaling pathway interactome.

Kwon Y, Vinayagam A, Sun X, Dephoure N, Gygi SP, Hong P, Perrimon N.

Science. 2013 Nov 8;342(6159):737-40. doi: 10.1126/science.1243971. Epub 2013 Oct 10.

17.

Changes in cell morphology are coordinated with cell growth through the TORC1 pathway.

Goranov AI, Gulati A, Dephoure N, Takahara T, Maeda T, Gygi SP, Manalis S, Amon A.

Curr Biol. 2013 Jul 22;23(14):1269-79. doi: 10.1016/j.cub.2013.05.035. Epub 2013 Jun 27.

18.

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.

Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC.

Mol Cell. 2013 Jun 6;50(5):686-98. doi: 10.1016/j.molcel.2013.05.012.

19.

Intramolecular interactions control Vms1 translocation to damaged mitochondria.

Heo JM, Nielson JR, Dephoure N, Gygi SP, Rutter J.

Mol Biol Cell. 2013 May;24(9):1263-73. doi: 10.1091/mbc.E13-02-0072. Epub 2013 Mar 6.

20.

Mapping and analysis of phosphorylation sites: a quick guide for cell biologists.

Dephoure N, Gould KL, Gygi SP, Kellogg DR.

Mol Biol Cell. 2013 Mar;24(5):535-42. doi: 10.1091/mbc.E12-09-0677. Review.

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