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Items: 1 to 20 of 48

1.

Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.

Gómez-Banoy N, Guseh JS, Li G, Rubio-Navarro A, Chen T, Poirier B, Putzel G, Rosselot C, Pabón MA, Camporez JP, Bhambhani V, Hwang SJ, Yao C, Perry RJ, Mukherjee S, Larson MG, Levy D, Dow LE, Shulman GI, Dephoure N, Garcia-Ocana A, Hao M, Spiegelman BM, Ho JE, Lo JC.

Nat Med. 2019 Nov;25(11):1739-1747. doi: 10.1038/s41591-019-0610-4. Epub 2019 Nov 7.

PMID:
31700183
2.

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.

Gomes AP, Ilter D, Low V, Rosenzweig A, Shen ZJ, Schild T, Rivas MA, Er EE, McNally DR, Mutvei AP, Han J, Ou YH, Cavaliere P, Mullarky E, Nagiec M, Shin S, Yoon SO, Dephoure N, Massagué J, Melnick AM, Cantley LC, Tyler JK, Blenis J.

Cancer Cell. 2019 Oct 14;36(4):402-417.e13. doi: 10.1016/j.ccell.2019.08.006. Epub 2019 Sep 26.

PMID:
31564638
3.

KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks.

Di Giammartino DC, Kloetgen A, Polyzos A, Liu Y, Kim D, Murphy D, Abuhashem A, Cavaliere P, Aronson B, Shah V, Dephoure N, Stadtfeld M, Tsirigos A, Apostolou E.

Nat Cell Biol. 2019 Oct;21(10):1179-1190. doi: 10.1038/s41556-019-0390-6. Epub 2019 Sep 23.

PMID:
31548608
4.

N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.

Berger A, Brady NJ, Bareja R, Robinson B, Conteduca V, Augello MA, Puca L, Ahmed A, Dardenne E, Lu X, Hwang I, Bagadion AM, Sboner A, Elemento O, Paik J, Yu J, Barbieri CE, Dephoure N, Beltran H, Rickman DS.

J Clin Invest. 2019 Jul 1;130:3924-3940. doi: 10.1172/JCI127961.

5.

Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins.

Caceres PS, Gravotta D, Zager PJ, Dephoure N, Rodriguez-Boulan E.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11796-11805. doi: 10.1073/pnas.1821076116. Epub 2019 May 29.

6.

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.

Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE.

Cancer Cell. 2019 May 13;35(5):817-819. doi: 10.1016/j.ccell.2019.04.012. No abstract available.

PMID:
31085180
7.

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program.

Kikani CK, Wu X, Fogarty S, Kang SAW, Dephoure N, Gygi SP, Sabatini DM, Rutter J.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10382-10391. doi: 10.1073/pnas.1804013116. Epub 2019 May 9.

8.

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.

Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE.

Cancer Cell. 2019 Apr 15;35(4):603-617.e8. doi: 10.1016/j.ccell.2019.03.001. Epub 2019 Mar 28. Erratum in: Cancer Cell. 2019 May 13;35(5):817-819.

PMID:
30930119
9.

Predicting peptide presentation by major histocompatibility complex class I: an improved machine learning approach to the immunopeptidome.

Boehm KM, Bhinder B, Raja VJ, Dephoure N, Elemento O.

BMC Bioinformatics. 2019 Jan 5;20(1):7. doi: 10.1186/s12859-018-2561-z.

10.

Robust, Reproducible, and Economical Phosphopeptide Enrichment Using Calcium Titanate.

Ahmed A, Raja VJ, Cavaliere P, Dephoure N.

J Proteome Res. 2019 Mar 1;18(3):1411-1417. doi: 10.1021/acs.jproteome.8b00883. Epub 2019 Jan 3.

PMID:
30576142
11.

Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells.

Hwang S, Gustafsson HT, O'Sullivan C, Bisceglia G, Huang X, Klose C, Schevchenko A, Dickson RC, Cavaliere P, Dephoure N, Torres EM.

Cell Rep. 2017 Dec 26;21(13):3807-3818. doi: 10.1016/j.celrep.2017.11.103.

12.

Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.

Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure NE, Blackwell TK, Yu JJ, Rabinowitz JD, Cantley LC, Blenis J.

Cell. 2017 Dec 14;171(7):1545-1558.e18. doi: 10.1016/j.cell.2017.10.037. Epub 2017 Nov 16.

13.

A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast.

Clarke J, Dephoure N, Horecka I, Gygi S, Kellogg D.

Mol Biol Cell. 2017 Oct 1;28(20):2589-2599. doi: 10.1091/mbc.E17-01-0081. Epub 2017 Aug 9.

14.

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.

Yoon SO, Shin S, Karreth FA, Buel GR, Jedrychowski MP, Plas DR, Dedhar S, Gygi SP, Roux PP, Dephoure N, Blenis J.

Mol Cell. 2017 Aug 3;67(3):512-527.e4. doi: 10.1016/j.molcel.2017.06.033. Epub 2017 Jul 27.

15.

Deep Coverage of Global Protein Expression and Phosphorylation in Breast Tumor Cell Lines Using TMT 10-plex Isobaric Labeling.

Huang FK, Zhang G, Lawlor K, Nazarian A, Philip J, Tempst P, Dephoure N, Neubert TA.

J Proteome Res. 2017 Mar 3;16(3):1121-1132. doi: 10.1021/acs.jproteome.6b00374. Epub 2017 Feb 3.

16.

Protein Kinase C Controls Binding of Igo/ENSA Proteins to Protein Phosphatase 2A in Budding Yeast.

Thai V, Dephoure N, Weiss A, Ferguson J, Leitao R, Gygi SP, Kellogg DR.

J Biol Chem. 2017 Mar 24;292(12):4925-4941. doi: 10.1074/jbc.M116.753004. Epub 2017 Jan 18.

17.

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation.

Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, Dephoure N, Satterstrom FK, Sheffer M, Spinelli JB, Gygi S, Rabinowitz JD, Sharpe AH, Haigis MC.

Cell Metab. 2016 Jul 12;24(1):104-17. doi: 10.1016/j.cmet.2016.06.007.

18.

Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks.

Zhou C, Elia AE, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3667-75. doi: 10.1073/pnas.1602827113. Epub 2016 Jun 13.

19.

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.

Mol Cell. 2015 Sep 3;59(5):867-81. doi: 10.1016/j.molcel.2015.05.006. Epub 2015 Jun 4.

20.

Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly.

Lucena R, Dephoure N, Gygi SP, Kellogg DR, Tallada VA, Daga RR, Jimenez J.

J Cell Biol. 2015 May 11;209(3):387-402. doi: 10.1083/jcb.201412144.

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