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Items: 1 to 20 of 81

1.

The HMG box transcription factor HBP1: a cell cycle inhibitor at the crossroads of cancer signaling pathways.

Bollaert E, de Rocca Serra A, Demoulin JB.

Cell Mol Life Sci. 2019 Jan 25. doi: 10.1007/s00018-019-03012-9. [Epub ahead of print] Review.

PMID:
30683982
2.

ALK positively regulates MYCN activity through repression of HBP1 expression.

Claeys S, Denecker G, Durinck K, Decaesteker B, Mus LM, Loontiens S, Vanhauwaert S, Althoff K, Wigerup C, Bexell D, Dolman E, Henrich KO, Wehrmann L, Westerhout EM, Demoulin JB, Kumps C, Van Maerken T, Laureys G, Van Neste C, De Wilde B, De Wever O, Westermann F, Versteeg R, Molenaar JJ, Påhlman S, Schulte JH, De Preter K, Speleman F.

Oncogene. 2018 Dec 11. doi: 10.1038/s41388-018-0595-3. [Epub ahead of print]

PMID:
30538293
3.

Atomistic mechanism of the constitutive activation of PDGFRA via its transmembrane domain.

Polyansky AA, Bocharov EV, Velghe AI, Kuznetsov AS, Bocharova OV, Urban AS, Arseniev AS, Zagrovic B, Demoulin JB, Efremov RG.

Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):82-95. doi: 10.1016/j.bbagen.2018.09.011. Epub 2018 Sep 22.

PMID:
30253204
4.

The gut microbiota metabolite indole alleviates liver inflammation in mice.

Beaumont M, Neyrinck AM, Olivares M, Rodriguez J, de Rocca Serra A, Roumain M, Bindels LB, Cani PD, Evenepoel P, Muccioli GG, Demoulin JB, Delzenne NM.

FASEB J. 2018 Jun 15:fj201800544. doi: 10.1096/fj.201800544. [Epub ahead of print]

5.

Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle.

Gnimassou O, Fernández-Verdejo R, Brook M, Naslain D, Balan E, Sayda M, Cegielski J, Nielens H, Decottignies A, Demoulin JB, Smith K, Atherton PJ, Francaux M, Deldicque L.

FASEB J. 2018 Oct;32(10):5272-5284. doi: 10.1096/fj.201800049RR. Epub 2018 Apr 19.

PMID:
29672220
6.

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation.

Bollaert E, Johanns M, Herinckx G, de Rocca Serra A, Vandewalle VA, Havelange V, Rider MH, Vertommen D, Demoulin JB.

Cell Signal. 2018 Apr;44:158-170. doi: 10.1016/j.cellsig.2018.01.014. Epub 2018 Feb 16.

PMID:
29355710
7.

A patient with germ-line gain-of-function PDGFRB p.N666H mutation and marked clinical response to imatinib.

Pond D, Arts FA, Mendelsohn NJ, Demoulin JB, Scharer G, Messinger Y.

Genet Med. 2018 Jan;20(1):142-150. doi: 10.1038/gim.2017.104. Epub 2017 Jul 20.

PMID:
28726812
8.

Germline CDKN2A/P16INK4A mutations contribute to genetic determinism of sarcoma.

Jouenne F, Chauvot de Beauchene I, Bollaert E, Avril MF, Caron O, Ingster O, Lecesne A, Benusiglio P, Terrier P, Caumette V, Pissaloux D, de la Fouchardière A, Cabaret O, N'Diaye B, Velghe A, Bougeard G, Mann GJ, Koscielny S, Barrett JH, Harland M, Newton-Bishop J, Gruis N, Van Doorn R, Gauthier-Villars M, Pierron G, Stoppa-Lyonnet D, Coupier I, Guimbaud R, Delnatte C, Scoazec JY, Eggermont AM, Feunteun J, Tchertanov L, Demoulin JB, Frebourg T, Bressac-de Paillerets B.

J Med Genet. 2017 Sep;54(9):607-612. doi: 10.1136/jmedgenet-2016-104402. Epub 2017 Jun 7.

9.

Unwanted acquired mutations in Ba/F3 transformation assays.

Demoulin JB, Dachy G, Arts FA.

Oncotarget. 2017 Mar 28;8(13):20523-20524. doi: 10.18632/oncotarget.16268. No abstract available.

10.

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.

Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4.

11.

PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.

Arts FA, Sciot R, Brichard B, Renard M, de Rocca Serra A, Dachy G, Noël LA, Velghe AI, Galant C, Debiec-Rychter M, Van Damme A, Vikkula M, Helaers R, Limaye N, Poirel HA, Demoulin JB.

Hum Mol Genet. 2017 May 15;26(10):1801-1810. doi: 10.1093/hmg/ddx081.

PMID:
28334876
12.

PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase.

Coomans de Brachène A, Dif N, de Rocca Serra A, Bonnineau C, Velghe AI, Larondelle Y, Tyteca D, Demoulin JB.

FEBS Open Bio. 2017 Feb 2;7(3):414-423. doi: 10.1002/2211-5463.12194. eCollection 2017 Mar.

13.

Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal muscle after exercise and facilitates molecular adaptation to endurance training.

Fernández-Verdejo R, Vanwynsberghe AM, Essaghir A, Demoulin JB, Hai T, Deldicque L, Francaux M.

FASEB J. 2017 Feb;31(2):840-851. doi: 10.1096/fj.201600987R. Epub 2016 Nov 17.

14.
15.

ABCB1 1199G>A polymorphism (rs2229109) affects the transport of imatinib, nilotinib and dasatinib.

Dessilly G, Elens L, Panin N, Karmani L, Demoulin JB, Haufroid V.

Pharmacogenomics. 2016 Jun;17(8):883-90. doi: 10.2217/pgs-2016-0012. Epub 2016 Jun 7.

PMID:
27268766
16.

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.

Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD.

Gut. 2017 Apr;66(4):620-632. doi: 10.1136/gutjnl-2015-310904. Epub 2016 May 5.

17.

FOXO transcription factors in cancer development and therapy.

Coomans de Brachène A, Demoulin JB.

Cell Mol Life Sci. 2016 Mar;73(6):1159-72. doi: 10.1007/s00018-015-2112-y. Epub 2015 Dec 19. Review.

PMID:
26686861
18.

PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib.

Arts FA, Chand D, Pecquet C, Velghe AI, Constantinescu S, Hallberg B, Demoulin JB.

Oncogene. 2016 Jun 23;35(25):3239-48. doi: 10.1038/onc.2015.383. Epub 2015 Oct 12.

PMID:
26455322
19.

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.

Geurts L, Everard A, Van Hul M, Essaghir A, Duparc T, Matamoros S, Plovier H, Castel J, Denis RG, Bergiers M, Druart C, Alhouayek M, Delzenne NM, Muccioli GG, Demoulin JB, Luquet S, Cani PD.

Nat Commun. 2015 Mar 11;6:6495. doi: 10.1038/ncomms7495.

20.

Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling.

Arts FA, Velghe AI, Stevens M, Renauld JC, Essaghir A, Demoulin JB.

J Cell Mol Med. 2015 Jan;19(1):239-48. doi: 10.1111/jcmm.12443. Epub 2014 Oct 8.

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