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Items: 1 to 20 of 113

1.

Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic.

Ludwicki MB, Li J, Stephens EA, Roberts RW, Koide S, Hammond PT, DeLisa MP.

ACS Cent Sci. 2019 May 22;5(5):852-866. doi: 10.1021/acscentsci.9b00127. Epub 2019 May 10.

2.

Dual Site-Specific Antibody Conjugates for Sequential and Orthogonal Cargo Release.

Thornlow DN, Cox EC, Walker JA, Sorkin M, Plesset JB, DeLisa MP, Alabi CA.

Bioconjug Chem. 2019 Jun 19;30(6):1702-1710. doi: 10.1021/acs.bioconjchem.9b00244. Epub 2019 May 24.

PMID:
31083974
3.

A survival selection strategy for engineering synthetic binding proteins that specifically recognize post-translationally phosphorylated proteins.

Meksiriporn B, Ludwicki MB, Stephens EA, Jiang A, Lee HC, Waraho-Zhmayev D, Kummer L, Brandl F, Pl├╝ckthun A, DeLisa MP.

Nat Commun. 2019 Apr 23;10(1):1830. doi: 10.1038/s41467-019-09854-y.

4.

Improving designer glycan production in Escherichia coli through model-guided metabolic engineering.

Wayman JA, Glasscock C, Mansell TJ, DeLisa MP, Varner JD.

Metab Eng Commun. 2019 Mar 29;9:e00088. doi: 10.1016/j.mec.2019.e00088. eCollection 2019 Dec.

5.

Antibody-Mediated Endocytosis of Polysialic Acid Enables Intracellular Delivery and Cytotoxicity of a Glycan-Directed Antibody-Drug Conjugate.

Cox EC, Thornlow DN, Jones MA, Fuller JL, Merritt JH, Paszek MJ, Alabi CA, DeLisa MP.

Cancer Res. 2019 Apr 15;79(8):1810-1821. doi: 10.1158/0008-5472.CAN-18-3119. Epub 2019 Feb 26.

PMID:
30808675
6.

Glyco-recoded Escherichia coli: Recombineering-based genome editing of native polysaccharide biosynthesis gene clusters.

Yates LE, Natarajan A, Li M, Hale ME, Mills DC, DeLisa MP.

Metab Eng. 2019 May;53:59-68. doi: 10.1016/j.ymben.2019.02.002. Epub 2019 Feb 14.

PMID:
30772453
7.

Engineering a new generation of carbohydrate-based vaccines.

Weyant KB, Mills DC, DeLisa MP.

Curr Opin Chem Eng. 2018 Mar;19:77-85. doi: 10.1016/j.coche.2017.12.009. Epub 2018 Jan 11.

8.

Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein.

Mahajan SP, Meksiriporn B, Waraho-Zhmayev D, Weyant KB, Kocer I, Butler DC, Messer A, Escobedo FA, DeLisa MP.

Sci Rep. 2018 Dec 4;8(1):17611. doi: 10.1038/s41598-018-35464-7.

9.

Interplay of Carbohydrate and Carrier in Antibacterial Glycoconjugate Vaccines.

Moeller TD, Weyant KB, DeLisa MP.

Adv Biochem Eng Biotechnol. 2018 Aug 25. doi: 10.1007/10_2018_71. [Epub ahead of print]

PMID:
30143807
10.

Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Aug 20;9(1):3396. doi: 10.1038/s41467-018-05620-8.

11.

Bacterial Glycoengineering as a Biosynthetic Route to Customized Glycomolecules.

Yates LE, Mills DC, DeLisa MP.

Adv Biochem Eng Biotechnol. 2018 Aug 12. doi: 10.1007/10_2018_72. [Epub ahead of print]

PMID:
30099598
12.

Design and Functional Characterization of Synthetic E3 Ubiquitin Ligases for Targeted Protein Depletion.

Baltz MR, Stephens EA, DeLisa MP.

Curr Protoc Chem Biol. 2018 Mar;10(1):72-90. doi: 10.1002/cpch.37.

13.

Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Jul 12;9(1):2686. doi: 10.1038/s41467-018-05110-x. Erratum in: Nat Commun. 2018 Aug 20;9(1):3396.

14.

Design of glycosylation sites by rapid synthesis and analysis of glycosyltransferases.

Kightlinger W, Lin L, Rosztoczy M, Li W, DeLisa MP, Mrksich M, Jewett MC.

Nat Chem Biol. 2018 Jun;14(6):627-635. doi: 10.1038/s41589-018-0051-2. Epub 2018 May 7.

PMID:
29736039
15.

A flow cytometric approach to engineering Escherichia coli for improved eukaryotic protein glycosylation.

Glasscock CJ, Yates LE, Jaroentomeechai T, Wilson JD, Merritt JH, Lucks JB, DeLisa MP.

Metab Eng. 2018 May;47:488-495. doi: 10.1016/j.ymben.2018.04.014. Epub 2018 Apr 25.

PMID:
29702274
16.

Immunization with outer membrane vesicles displaying conserved surface polysaccharide antigen elicits broadly antimicrobial antibodies.

Stevenson TC, Cywes-Bentley C, Moeller TD, Weyant KB, Putnam D, Chang YF, Jones BD, Pier GB, DeLisa MP.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3106-E3115. doi: 10.1073/pnas.1718341115. Epub 2018 Mar 19.

17.

A cell-free platform for rapid synthesis and testing of active oligosaccharyltransferases.

Schoborg JA, Hershewe JM, Stark JC, Kightlinger W, Kath JE, Jaroentomeechai T, Natarajan A, DeLisa MP, Jewett MC.

Biotechnol Bioeng. 2018 Mar;115(3):739-750. doi: 10.1002/bit.26502. Epub 2017 Dec 26.

PMID:
29178580
18.

A library of chemically defined human N-glycans synthesized from microbial oligosaccharide precursors.

Hamilton BS, Wilson JD, Shumakovich MA, Fisher AC, Brooks JC, Pontes A, Naran R, Heiss C, Gao C, Kardish R, Heimburg-Molinaro J, Azadi P, Cummings RD, Merritt JH, DeLisa MP.

Sci Rep. 2017 Nov 21;7(1):15907. doi: 10.1038/s41598-017-15891-8.

19.

A Pipeline for Studying and Engineering Single-Subunit Oligosaccharyltransferases.

Jaroentomeechai T, Zheng X, Hershewe J, Stark JC, Jewett MC, DeLisa MP.

Methods Enzymol. 2017;597:55-81. doi: 10.1016/bs.mie.2017.07.011. Epub 2017 Sep 13.

PMID:
28935112
20.

A single dose and long lasting vaccine against pandemic influenza through the controlled release of a heterospecies tandem M2 sequence embedded within detoxified bacterial outer membrane vesicles.

Watkins HC, Pagan CL, Childs HR, Posada S, Chau A, Rios J, Guarino C, DeLisa MP, Whittaker GR, Putnam D.

Vaccine. 2017 Sep 25;35(40):5373-5380. doi: 10.1016/j.vaccine.2017.08.013. Epub 2017 Aug 31.

PMID:
28866291

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