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Items: 1 to 20 of 46

1.

Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study).

Lloret-Linares C, Daali Y, Chevret S, Nieto I, Molière F, Courtet P, Galtier F, Richieri RM, Morange S, Llorca PM, El-Hage W, Desmidt T, Haesebaert F, Vignaud P, Holtzmann J, Cracowski JL, Leboyer M, Yrondi A, Calvas F, Yon L, Le Corvoisier P, Doumy O, Heron K, Montange D, Davani S, Déglon J, Besson M, Desmeules J, Haffen E, Bellivier F.

BMC Pharmacol Toxicol. 2017 Nov 7;18(1):70. doi: 10.1186/s40360-017-0173-2.

2.

In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system.

Petit-Pierre G, Colin P, Laurer E, Déglon J, Bertsch A, Thomas A, Schneider BL, Renaud P.

Nat Commun. 2017 Nov 1;8(1):1239. doi: 10.1038/s41467-017-01419-1.

3.

Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.

Bosilkovska M, Samer C, Déglon J, Thomas A, Walder B, Desmeules J, Daali Y.

Basic Clin Pharmacol Toxicol. 2016 Sep;119(3):284-90. doi: 10.1111/bcpt.12586. Epub 2016 Apr 25.

4.

Potential missing steps for a wide use of dried matrix spots in biomedical analysis.

Déglon J, Leuthold LA, Thomas A.

Bioanalysis. 2015 Sep;7(18):2375-2385. doi: 10.4155/bio.15.166. Epub 2015 Sep 17.

PMID:
26378369
5.

New microfluidic-based sampling procedure for overcoming the hematocrit problem associated with dried blood spot analysis.

Leuthold LA, Heudi O, Déglon J, Raccuglia M, Augsburger M, Picard F, Kretz O, Thomas A.

Anal Chem. 2015 Feb 17;87(4):2068-71. doi: 10.1021/ac503931g. Epub 2015 Jan 30.

PMID:
25607538
6.

Application of direct-infusion ESI-MS/MS for toxicological screening.

Versace F, Déglon J, Mangin P, Staub C.

Bioanalysis. 2014 Aug;6(15):2043-55. doi: 10.4155/bio.14.58.

PMID:
25322781
7.

Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots.

Bosilkovska M, Samer CF, Déglon J, Rebsamen M, Staub C, Dayer P, Walder B, Desmeules JA, Daali Y.

Clin Pharmacol Ther. 2014 Sep;96(3):349-59. doi: 10.1038/clpt.2014.83. Epub 2014 Apr 10.

8.

Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.

Bosilkovska M, Déglon J, Samer C, Walder B, Desmeules J, Staub C, Daali Y.

Bioanalysis. 2014 Jan;6(2):151-64. doi: 10.4155/bio.13.289.

PMID:
24423593
9.

Body fluid and tissue analysis using filter paper sampling support prior to LC-MS/MS: application to fatal overdose with colchicine.

Lauer E, Widmer C, Versace F, Staub C, Mangin P, Sabatasso S, Augsburger M, Déglon J.

Drug Test Anal. 2013 Sep-Oct;5(9-10):763-72. doi: 10.1002/dta.1496. Epub 2013 May 16.

PMID:
23682018
10.

Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers.

Ancrenaz V, Déglon J, Samer C, Staub C, Dayer P, Daali Y, Desmeules J.

Basic Clin Pharmacol Toxicol. 2013 Feb;112(2):132-7. doi: 10.1111/j.1742-7843.2012.00932.x. Epub 2012 Oct 5.

11.

Rapid LC-MS/MS quantification of the major benzodiazepines and their metabolites on dried blood spots using a simple and cost-effective sample pretreatment.

Déglon J, Versace F, Lauer E, Widmer C, Mangin P, Thomas A, Staub C.

Bioanalysis. 2012 Jun;4(11):1337-50. doi: 10.4155/bio.12.42.

PMID:
22720652
12.

A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry.

Ansari M, Uppugunduri CR, Déglon J, Théorêt Y, Versace F, Gumy-Pause F, Ozsahin H, Dayer P, Desmules J, Daali Y.

Rapid Commun Mass Spectrom. 2012 Jun 30;26(12):1437-46. doi: 10.1002/rcm.6241.

PMID:
22592987
13.

Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot.

Daali Y, Samer C, Déglon J, Thomas A, Chabert J, Rebsamen M, Staub C, Dayer P, Desmeules J.

Clin Pharmacol Ther. 2012 Mar;91(3):489-96. doi: 10.1038/clpt.2011.247. Epub 2012 Jan 11.

PMID:
22237256
14.

Direct analysis of dried blood spots coupled with mass spectrometry: concepts and biomedical applications.

Déglon J, Thomas A, Mangin P, Staub C.

Anal Bioanal Chem. 2012 Mar;402(8):2485-98. doi: 10.1007/s00216-011-5161-6. Epub 2011 Jun 25. Review.

PMID:
21706235
15.

Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics.

Thomas A, Lenglet S, Chaurand P, Deglon J, Mangin P, Mach F, Steffens S, Wolfender JL, Staub C.

Thromb Haemost. 2011 Jul;106(1):20-33. doi: 10.1160/TH10-12-0812. Epub 2011 May 26. Review.

PMID:
21614412
16.

Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite.

Déglon J, Thomas A, Daali Y, Lauer E, Samer C, Desmeules J, Dayer P, Mangin P, Staub C.

J Pharm Biomed Anal. 2011 Jan 25;54(2):359-67. doi: 10.1016/j.jpba.2010.08.032.

PMID:
20864289
17.

High-throughput phospholipidic fingerprinting by online desorption of dried spots and quadrupole-linear ion trap mass spectrometry: evaluation of atherosclerosis biomarkers in mouse plasma.

Thomas A, Déglon J, Lenglet S, Mach F, Mangin P, Wolfender JL, Steffens S, Staub C.

Anal Chem. 2010 Aug 1;82(15):6687-94.

PMID:
20700914
18.

High-Throughput Phospholipidic Fingerprinting by Online Desorption of Dried Spots and Quadrupole-Linear Ion Trap Mass Spectrometry: Evaluation of Atherosclerosis Biomarkers in Mouse Plasma.

Thomas A, Déglon J, Lenglet S, Mach F, Mangin P, Wolfender JL, Steffens S, Staub C.

Anal Chem. 2010 Aug 1;82(15):6687-6694.

PMID:
20698582
19.

Substitution of (R,S)-methadone by (R)-methadone: Impact on QTc interval.

Ansermot N, Albayrak O, Schläpfer J, Crettol S, Croquette-Krokar M, Bourquin M, Déglon JJ, Faouzi M, Scherbaum N, Eap CB.

Arch Intern Med. 2010 Mar 22;170(6):529-36. doi: 10.1001/archinternmed.2010.26.

PMID:
20308640
20.

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