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Items: 18


Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.

Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736.


Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.

Arpaia N, Campbell C, Fan X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR, Pfeffer K, Coffer PJ, Rudensky AY.

Nature. 2013 Dec 19;504(7480):451-5. doi: 10.1038/nature12726. Epub 2013 Nov 13.


Transcription factor Foxp3 and its protein partners form a complex regulatory network.

Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY.

Nat Immunol. 2012 Oct;13(10):1010-9. doi: 10.1038/ni.2402. Epub 2012 Aug 26.


Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice.

Kim J, Lahl K, Hori S, Loddenkemper C, Chaudhry A, deRoos P, Rudensky A, Sparwasser T.

J Immunol. 2009 Dec 15;183(12):7631-4. doi: 10.4049/jimmunol.0804308.


Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses.

Zheng Y, Chaudhry A, Kas A, deRoos P, Kim JM, Chu TT, Corcoran L, Treuting P, Klein U, Rudensky AY.

Nature. 2009 Mar 19;458(7236):351-6. doi: 10.1038/nature07674. Epub 2009 Feb 1.


Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development.

Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6659-64. Epub 2006 Apr 14. Erratum in: Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9373.


Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes.

Barton GM, Beers C, deRoos P, Eastman SR, Gomez ME, Forbush KA, Rudensky AY.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6937-42.


A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation.

Hsieh CS, deRoos P, Honey K, Beers C, Rudensky AY.

J Immunol. 2002 Mar 15;168(6):2618-25.


In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses.

Dongre AR, Kovats S, deRoos P, McCormack AL, Nakagawa T, Paharkova-Vatchkova V, Eng J, Caldwell H, Yates JR 3rd, Rudensky AY.

Eur J Immunol. 2001 May;31(5):1485-94.


Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo.

Kovats S, Grubin CE, Eastman S, deRoos P, Dongre A, Van Kaer L, Rudensky AY.

J Exp Med. 1998 Jan 19;187(2):245-51.


A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody.

Eastman S, Deftos M, DeRoos PC, Hsu DH, Teyton L, Braunstein NS, Hackett CJ, Rudensky A.

Eur J Immunol. 1996 Feb;26(2):385-93.


Intracellular assembly and transport of endogenous peptide-MHC class II complexes.

Rudensky AY, Maric M, Eastman S, Shoemaker L, DeRoos PC, Blum JS.

Immunity. 1994 Oct;1(7):585-94.


Enhanced hematopoietic activity of a human granulocyte/macrophage colony-stimulating factor-interleukin 3 fusion protein.

Curtis BM, Williams DE, Broxmeyer HE, Dunn J, Farrah T, Jeffery E, Clevenger W, deRoos P, Martin U, Friend D, et al.

Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5809-13.


IL-1 and its receptor are translocated to the nucleus.

Curtis BM, Widmer MB, deRoos P, Qwarnstrom EE.

J Immunol. 1990 Feb 15;144(4):1295-303.


T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

Curtis BM, Gallis B, Overell RW, McMahan CJ, DeRoos P, Ireland R, Eisenman J, Dower SK, Sims JE.

Proc Natl Acad Sci U S A. 1989 May;86(9):3045-9.

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