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Items: 1 to 20 of 29

1.

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.

Jeyakumar T, Fodil N, Van Der Kraak L, Meunier C, Cayrol R, McGregor K, Langlais D, Greenwood CMT, Beauchemin N, Gros P.

Sci Rep. 2019 Dec 11;9(1):18897. doi: 10.1038/s41598-019-55378-2.

2.

ZBTB7B (ThPOK) IS REQUIRED FOR PATHOGENESIS OF CEREBRAL MALARIA AND PROTECTION AGAINST PULMONARY TUBERCULOSIS.

Kennedy JM, Georges A, Bassenden AV, Vidal SM, Berghuis AM, Taniuchi I, Majewski J, Lathrop M, Behr MA, Langlais D, Gros P.

Infect Immun. 2019 Dec 2. pii: IAI.00845-19. doi: 10.1128/IAI.00845-19. [Epub ahead of print]

PMID:
31792077
3.

USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model.

Lin YH, Forster M, Liang Y, Yu M, Wang H, Robert F, Langlais D, Pelletier J, Clare S, Nijnik A.

Exp Hematol. 2019 Apr;72:1-8. doi: 10.1016/j.exphem.2019.01.001. Epub 2019 Jan 9.

PMID:
30639577
4.

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.

Kong XF, Martinez-Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick EK, Ma CS, Breton G, Lucero KB, Langlais D, Bousfiha A, Aytekin C, Markle J, Trouillet C, Jabot-Hanin F, Arlehamn CSL, Rao G, Picard C, Lasseau T, Latorre D, Hambleton S, Deswarte C, Itan Y, Abarca K, Moraes-Vasconcelos D, Ailal F, Ikinciogullari A, Dogu F, Benhsaien I, Sette A, Abel L, Boisson-Dupuis S, Schröder B, Nussenzweig MC, Liu K, Geissmann F, Tangye SG, Gros P, Sallusto F, Bustamante J, Casanova JL.

Nat Immunol. 2018 Sep;19(9):973-985. doi: 10.1038/s41590-018-0178-z. Epub 2018 Aug 20.

5.

Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei.

Torre S, Langlais D, Gros P.

Mamm Genome. 2018 Aug;29(7-8):488-506. doi: 10.1007/s00335-018-9752-9. Epub 2018 Jun 19. Review.

PMID:
29922917
6.

Rocaglates as dual-targeting agents for experimental cerebral malaria.

Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA Jr, Pelletier J, Gros P.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2366-E2375. doi: 10.1073/pnas.1713000115. Epub 2018 Feb 20.

7.

Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus.

Rojo R, Pridans C, Langlais D, Hume DA.

Clin Sci (Lond). 2017 Jul 31;131(16):2161-2182. doi: 10.1042/CS20170238. Print 2017 Aug 15. Review.

PMID:
28760770
8.

Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.

Sheth R, Barozzi I, Langlais D, Osterwalder M, Nemec S, Carlson HL, Stadler HS, Visel A, Drouin J, Kmita M.

Cell Rep. 2016 Dec 13;17(11):2913-2926. doi: 10.1016/j.celrep.2016.11.039.

9.

Genetics of Infectious and Inflammatory Diseases: Overlapping Discoveries from Association and Exome-Sequencing Studies.

Langlais D, Fodil N, Gros P.

Annu Rev Immunol. 2017 Apr 26;35:1-30. doi: 10.1146/annurev-immunol-051116-052442. Epub 2016 Dec 1. Review.

PMID:
27912315
10.

Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2016 Nov 16;17(12):1479. doi: 10.1038/ni1216-1479c. No abstract available.

PMID:
27849203
11.

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581. Epub 2016 Oct 10. Erratum in: Nat Immunol. 2016 Nov 16;17 (12 ):1479.

PMID:
27721430
12.

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

Langlais D, Barreiro LB, Gros P.

J Exp Med. 2016 Apr 4;213(4):585-603. doi: 10.1084/jem.20151764. Epub 2016 Mar 21.

13.

Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.

Van Der Kraak L, Langlais D, Jothy S, Beauchemin N, Gros P.

Mamm Genome. 2016 Jun;27(5-6):213-24. doi: 10.1007/s00335-016-9625-z. Epub 2016 Mar 15.

PMID:
26979842
14.

Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.

Fodil N, Langlais D, Gros P.

Trends Immunol. 2016 Feb;37(2):126-140. doi: 10.1016/j.it.2015.12.006. Epub 2016 Jan 12. Review.

15.

Identification of Groundwater Nitrate Contamination from Explosives Used in Road Construction: Isotopic, Chemical, and Hydrologic Evidence.

Degnan JR, Böhlke JK, Pelham K, Langlais DM, Walsh GJ.

Environ Sci Technol. 2016 Jan 19;50(2):593-603. doi: 10.1021/acs.est.5b03671. Epub 2015 Dec 28.

PMID:
26709616
16.

The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease.

Roussel-Gervais A, Couture C, Langlais D, Takayasu S, Balsalobre A, Rueda BR, Zukerberg LR, Figarella-Branger D, Brue T, Drouin J.

J Clin Endocrinol Metab. 2016 Feb;101(2):513-22. doi: 10.1210/jc.2015-3324. Epub 2015 Dec 22.

PMID:
26695862
17.

p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.

Belle JI, Langlais D, Petrov JC, Pardo M, Jones RG, Gros P, Nijnik A.

Blood. 2015 Apr 9;125(15):2344-8. doi: 10.1182/blood-2014-05-574111. Epub 2015 Feb 20.

PMID:
25710881
18.

Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection.

Fodil N, Langlais D, Moussa P, Boivin GA, Di Pietrantonio T, Radovanovic I, Dumaine A, Blanchette M, Schurr E, Gros P, Vidal SM.

PLoS Pathog. 2014 Dec 4;10(12):e1004511. doi: 10.1371/journal.ppat.1004511. eCollection 2014 Dec.

19.

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.

Kennedy JM, Fodil N, Torre S, Bongfen SE, Olivier JF, Leung V, Langlais D, Meunier C, Berghout J, Langat P, Schwartzentruber J, Majewski J, Lathrop M, Vidal SM, Gros P.

J Exp Med. 2014 Dec 15;211(13):2519-35. doi: 10.1084/jem.20140455. Epub 2014 Nov 17.

20.

Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation.

Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P.

Blood. 2014 Sep 18;124(12):1894-904.

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