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Cysteine proteases during larval migration and development of helminths in their final host.

Grote A, Caffrey CR, Rebello KM, Smith D, Dalton JP, Lustigman S.

PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0005919. doi: 10.1371/journal.pntd.0005919. eCollection 2018 Aug. Review.


Cysteine proteases as digestive enzymes in parasitic helminths.

Caffrey CR, Goupil L, Rebello KM, Dalton JP, Smith D.

PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0005840. doi: 10.1371/journal.pntd.0005840. eCollection 2018 Aug. Review.


Low allelic diversity in vaccine candidates genes from different locations sustain hope for Fasciola hepatica immunization.

Dominguez MF, González-Miguel J, Carmona C, Dalton JP, Cwiklinski K, Tort J, Siles-Lucas M.

Vet Parasitol. 2018 Jul 15;258:46-52. doi: 10.1016/j.vetpar.2018.06.011. Epub 2018 Jun 11.


Immune Mechanisms Involved in Schistosoma mansoni-Cathepsin B Vaccine Induced Protection in Mice.

Ricciardi A, Zelt NH, Visitsunthorn K, Dalton JP, Ndao M.

Front Immunol. 2018 Jul 25;9:1710. doi: 10.3389/fimmu.2018.01710. eCollection 2018.


In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles.

McVeigh P, Cwiklinski K, Garcia-Campos A, Mulcahy G, O'Neill SM, Maule AG, Dalton JP.

Sci Rep. 2018 Aug 3;8(1):11700. doi: 10.1038/s41598-018-29673-3.


The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma.

Tanaka A, Allam VSRR, Simpson J, Tiberti N, Shiels J, To J, Lund M, Combes V, Weldon S, Taggart C, Dalton JP, Phipps S, Sukkar MB, Donnelly S.

J Allergy Clin Immunol. 2018 Jun;141(6):2316-2319. doi: 10.1016/j.jaci.2018.01.050. Epub 2018 Mar 6. No abstract available.


Advances in Fasciola hepatica research using 'omics' technologies.

Cwiklinski K, Dalton JP.

Int J Parasitol. 2018 Apr;48(5):321-331. doi: 10.1016/j.ijpara.2017.12.001. Epub 2018 Feb 21. Review.


Antibody recognition of cathepsin L1-derived peptides in Fasciola hepatica-infected and/or vaccinated cattle and identification of protective linear B-cell epitopes.

Garza-Cuartero L, Geurden T, Mahan SM, Hardham JM, Dalton JP, Mulcahy G.

Vaccine. 2018 Feb 8;36(7):958-968. doi: 10.1016/j.vaccine.2018.01.020. Epub 2018 Jan 17.


Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host.

Cwiklinski K, Jewhurst H, McVeigh P, Barbour T, Maule AG, Tort J, O'Neill SM, Robinson MW, Donnelly S, Dalton JP.

Mol Cell Proteomics. 2018 Apr;17(4):792-809. doi: 10.1074/mcp.RA117.000445. Epub 2018 Jan 10.


Protection against Schistosoma haematobium infection in hamsters by immunization with Schistosoma mansoni gut-derived cysteine peptidases, SmCB1 and SmCL3.

Tallima H, Abou El Dahab M, Kareem S, Dalton JP, El Ridi R.

Vaccine. 2017 Dec 15;35(50):6977-6983. doi: 10.1016/j.vaccine.2017.10.069. Epub 2017 Nov 6.


Proteomic Analysis of Extracellular HMGB1 Identifies Binding Partners and Exposes Its Potential Role in Airway Epithelial Cell Homeostasis.

Wong SL, To J, Santos J, Allam VSRR, Dalton JP, Djordjevic SP, Donnelly S, Padula MP, Sukkar MB.

J Proteome Res. 2018 Jan 5;17(1):33-45. doi: 10.1021/acs.jproteome.7b00212. Epub 2017 Nov 14.


Do surgical helmet systems affect intraoperative wound contamination? A randomised controlled trial.

Shirley OC, Bayan A, Zhu M, Dalton JP, Wiles S, Young SW.

Arch Orthop Trauma Surg. 2017 Nov;137(11):1565-1569. doi: 10.1007/s00402-017-2795-7. Epub 2017 Sep 16.


Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica.

Ruiz-Campillo MT, Molina Hernandez V, Escamilla A, Stevenson M, Perez J, Martinez-Moreno A, Donnelly S, Dalton JP, Cwiklinski K.

Sci Rep. 2017 Jun 5;7(1):2782. doi: 10.1038/s41598-017-03094-0.


The development of sexual stage malaria gametocytes in a Wave Bioreactor.

Demanga CG, Eng JWL, Gardiner DL, Roth A, Butterworth A, Adams JH, Trenholme KR, Dalton JP.

Parasit Vectors. 2017 May 2;10(1):216. doi: 10.1186/s13071-017-2155-z.


A Novel Restraint Device for Injection of Galleria mellonella Larvae that Minimizes the Risk of Accidental Operator Needle Stick Injury.

Dalton JP, Uy B, Swift S, Wiles S.

Front Cell Infect Microbiol. 2017 Mar 28;7:99. doi: 10.3389/fcimb.2017.00099. eCollection 2017.


Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase.

Tallima H, Dvořák J, Kareem S, Abou El Dahab M, Abdel Aziz N, Dalton JP, El Ridi R.

PLoS Negl Trop Dis. 2017 Mar 27;11(3):e0005443. doi: 10.1371/journal.pntd.0005443. eCollection 2017 Mar.


Recombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe2+/H+exchanger.

Labarbuta P, Duckett K, Botting CH, Chahrour O, Malone J, Dalton JP, Law CJ.

Sci Rep. 2017 Feb 15;7:42850. doi: 10.1038/srep42850.


Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms.

Dalton JP, Uy B, Phummarin N, Copp BR, Denny WA, Swift S, Wiles S.

PeerJ. 2016 Nov 22;4:e2717. eCollection 2016.


A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis.

Lund ME, Greer J, Dixit A, Alvarado R, McCauley-Winter P, To J, Tanaka A, Hutchinson AT, Robinson MW, Simpson AM, O'Brien BA, Dalton JP, Donnelly S.

Sci Rep. 2016 Nov 24;6:37789. doi: 10.1038/srep37789.


Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model.

Dalton JP, Uy B, Okuda KS, Hall CJ, Denny WA, Crosier PS, Swift S, Wiles S.

J Antimicrob Chemother. 2017 Feb;72(2):421-427. doi: 10.1093/jac/dkw421. Epub 2016 Oct 24.


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