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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 1
2012 1
2013 3
2014 2
2015 1
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2019 3
2020 3
2021 8
2022 1
2024 0

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23 results

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Page 1
Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma.
Yang L, He YT, Dong S, Wei XW, Chen ZH, Zhang B, Chen WD, Yang XR, Wang F, Shang XM, Zhong WZ, Wu YL, Zhou Q. Yang L, et al. J Immunother Cancer. 2022 Jan;10(2):e003534. doi: 10.1136/jitc-2021-003534. J Immunother Cancer. 2022. PMID: 35140113 Free PMC article.
METHODS: We used single-cell transcriptome sequencing and multiplex immunohistochemistry to investigate the immune microenvironment of EGFR-mutant and EGFR wild-type LUADs and determined the efficacy of immunotherapy. ...EGFR-mutant LUAD lacked CD8(+) tissue- …
METHODS: We used single-cell transcriptome sequencing and multiplex immunohistochemistry to investigate the immune microenvironment of EG …
The Role of CXCL13 and CXCL9 in Early Breast Cancer.
Razis E, Kalogeras KT, Kotsantis I, Koliou GA, Manousou K, Wirtz R, Veltrup E, Patsea H, Poulakaki N, Dionysopoulos D, Pervana S, Gogas H, Koutras A, Pentheroudakis G, Christodoulou C, Linardou H, Pavlakis K, Koletsa T, Pectasides D, Zagouri F, Fountzilas G. Razis E, et al. Clin Breast Cancer. 2020 Feb;20(1):e36-e53. doi: 10.1016/j.clbc.2019.08.008. Epub 2019 Sep 5. Clin Breast Cancer. 2020. PMID: 31699671

RESULTS: CXCL13 was correlated with CXCL9 (rho = 0.52; P < .001). High-expressing CXL13 and CXCL9 tumors had higher Ki67 and tumor infiltrating lymphocyte density (P-values < .001). ...Patients with low CXCL13 and high CXCL9 expression had shorter DFS and OS c

…

RESULTS: CXCL13 was correlated with CXCL9 (rho = 0.52; P < .001). High-expressing CXL13 and CXCL9 tumors had higher Ki67 and tumor

…
Dysregulation of T(FH)-B-T(RM) lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer.
Cho JW, Park S, Kim G, Han H, Shim HS, Shin S, Bae YS, Park SY, Ha SJ, Lee I, Kim HR. Cho JW, et al. Nat Commun. 2021 Oct 18;12(1):6068. doi: 10.1038/s41467-021-26362-0. Nat Commun. 2021. PMID: 34663810 Free PMC article.
Hypothesizing that EGFR mutations alter tumor-immune interactions, we compare tumor-infiltrating lymphocytes between EGFR mutant (EGFR-MT) and wild type (EGFR-WT) tumors through single-cell transcriptomic analysis. We find that B cells, CXCL13-p …
Hypothesizing that EGFR mutations alter tumor-immune interactions, we compare tumor-infiltrating lymphocytes between EGFR muta …
CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells.
Li G, Guo J, Zheng Y, Ding W, Han Z, Qin L, Mo W, Luo M. Li G, et al. Mol Ther Oncolytics. 2021 Jul 16;22:507-517. doi: 10.1016/j.omto.2021.07.003. eCollection 2021 Sep 24. Mol Ther Oncolytics. 2021. PMID: 34553036 Free PMC article.
One promising strategy is to guide T cells through tumor-specific chemokines, provided that the matching chemokine receptors are expressed on T cells. Previous reports showed that, for non-small cell lung cancer (NSCLC) patients, the tumor sites express high levels …
One promising strategy is to guide T cells through tumor-specific chemokines, provided that the matching chemokine receptors a …
Gastric Damage and Cancer-Associated Biomarkers in Helicobacter pylori-Infected Children.
George S, Lucero Y, Torres JP, Lagomarcino AJ, O'Ryan M. George S, et al. Front Microbiol. 2020 Feb 12;11:90. doi: 10.3389/fmicb.2020.00090. eCollection 2020. Front Microbiol. 2020. PMID: 32117120 Free PMC article. Review.
Importantly, 13 of these biomarkers (beta-catenin, C-MYC, GATA-4, DAPK1, CXCL13, DC-SIGN, TIMP3, EGFR, GRIN2B, PIM2, SLC5A8, CDH1, and VCAM-1.) are consistently deregulated in infected children and in adults with gastric cancer. ...
Importantly, 13 of these biomarkers (beta-catenin, C-MYC, GATA-4, DAPK1, CXCL13, DC-SIGN, TIMP3, EGFR, GRIN2B, PIM2, SLC5A8, C …
Bioinformatic analyses suggest augmented interleukin-17 signaling as the mechanism of COVID-19-associated herpes zoster.
Yu X, Li L, Chan MTV, Wu WKK. Yu X, et al. Environ Sci Pollut Res Int. 2021 Dec;28(46):65769-65775. doi: 10.1007/s11356-021-15567-x. Epub 2021 Jul 28. Environ Sci Pollut Res Int. 2021. PMID: 34322810 Free PMC article.
Protein-protein interaction network assay showed that the combined gene set indicated a raised connectivity as compared to herpes zoster or COVID-19 alone, particularly the potentiated interactions with APOE, ARSA, CCR2, CCR5, CXCL13, EGFR, GAL, GP2, HLA-B, HLA-DRB1 …
Protein-protein interaction network assay showed that the combined gene set indicated a raised connectivity as compared to herpes zoster or …
Improved outcome of high-risk early HER2 positive breast cancer with high CXCL13-CXCR5 messenger RNA expression.
Razis E, Kalogeras KT, Kotoula V, Eleftheraki AG, Nikitas N, Kronenwett R, Timotheadou E, Christodoulou C, Pectasides D, Gogas H, Wirtz RM, Makatsoris T, Bafaloukos D, Aravantinos G, Televantou D, Pavlidis N, Fountzilas G. Razis E, et al. Clin Breast Cancer. 2012 Jun;12(3):183-93. doi: 10.1016/j.clbc.2012.03.006. Clin Breast Cancer. 2012. PMID: 22607768
The CXCL13-CXCR5 is a chemokine axis that is activated in some breast cancers. ...Interestingly, this chemokine axis seems to be strongly associated with improved outcome in patients with HER2(+) disease....
The CXCL13-CXCR5 is a chemokine axis that is activated in some breast cancers. ...Interestingly, this chemokine axis se …
[Clinical pathologic characteristics of extranodal follicular dendritic cell sarcoma].
Cui LF, Zhang JX, Li Z, Gao Y, Lu T, Zhao HY, Zhong DR. Cui LF, et al. Zhonghua Zhong Liu Za Zhi. 2019 Mar 23;41(3):218-222. doi: 10.3760/cma.j.issn.0253-3766.2019.03.012. Zhonghua Zhong Liu Za Zhi. 2019. PMID: 30917459 Chinese.
The results of immunohistochemistry showed that, the tumor cells were diffusely or focally positive for CD21, CD23, CD35, D2-40, EGFR and CXCL13, but negative for S-100, CD68, HMB45, SMA, Desmin, CD117, Dog-1, CD34, CD30, EMA and CK.Five cases were positive for PD-L …
The results of immunohistochemistry showed that, the tumor cells were diffusely or focally positive for CD21, CD23, CD35, D2-40, EGFR …
Tertiary lymphoid organs are associated with the progression of kidney damage and regulated by interleukin-17A.
Luo R, Cheng Y, Chang D, Liu T, Liu L, Pei G, Zhang N, Wang Z, Guo K, Chen W, Li M, Fan L, Zhang C, Li Y, Dai W, Zuo M, Xu Y, Yao Y, Ge S, Xu G. Luo R, et al. Theranostics. 2021 Jan 1;11(1):117-131. doi: 10.7150/thno.48624. eCollection 2021. Theranostics. 2021. PMID: 33391465 Free PMC article.
Results: We demonstrated that renal TLOs of IgA nephropathy patients were associated with disease severity and were independent risk factors for renal progression after adjustment for age, sex, mean arterial pressure, proteinuria and, baseline eGFR and MEST-C score, especi …
Results: We demonstrated that renal TLOs of IgA nephropathy patients were associated with disease severity and were independent risk factors …
Increased circulating Tfh to Tfr ratio in chronic renal allograft dysfunction: a pilot study.
Yan L, Li Y, Li Y, Wu X, Wang X, Wang L, Shi Y, Tang J. Yan L, et al. BMC Immunol. 2019 Aug 5;20(1):26. doi: 10.1186/s12865-019-0308-x. BMC Immunol. 2019. PMID: 31382877 Free PMC article.
The cTfh to cTfr ratio in CAD group was significantly higher than that in stable group (55.4 vs 25.3, P = 0.013). Serum CXCL13 in CAD group was significantly higher than stable group (30.4 vs 21.9 ng/ml, P = 0.025). After linear regression analysis, the cTfh to cTfr ratio …
The cTfh to cTfr ratio in CAD group was significantly higher than that in stable group (55.4 vs 25.3, P = 0.013). Serum CXCL13 in CAD …
23 results