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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1978 1
1980 2
1981 7
1982 8
1983 17
1984 21
1985 24
1986 22
1987 25
1988 16
1989 35
1990 35
1991 43
1992 34
1993 33
1994 41
1995 44
1996 31
1997 23
1998 27
1999 31
2000 33
2001 33
2002 35
2003 28
2004 21
2005 16
2006 33
2007 25
2008 31
2009 25
2010 19
2011 27
2012 26
2013 30
2014 22
2015 22
2016 21
2017 13
2018 27
2019 21
2020 26
2021 14
2022 15
2023 18
2024 12

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1,046 results

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Page 1
Generalized fear after acute stress is caused by change in neuronal cotransmitter identity.
Li HQ, Jiang W, Ling L, Pratelli M, Chen C, Gupta V, Godavarthi SK, Spitzer NC. Li HQ, et al. Science. 2024 Mar 15;383(6688):1252-1259. doi: 10.1126/science.adj5996. Epub 2024 Mar 14. Science. 2024. PMID: 38484078
Corticosterone release and activation of glucocorticoid receptors mediated the switch, and prompt antidepressant treatment blocked the cotransmitter switch and generalized fear. Our results provide important insight into the mechanisms involved in fear generalization....
Corticosterone release and activation of glucocorticoid receptors mediated the switch, and prompt antidepressant treatment blocked the co …
Editorial - Purinergic signalling: 50 years.
Illes P, Di Virgilio F, Tang Y. Illes P, et al. Neuropharmacology. 2024 Mar 1;245:109826. doi: 10.1016/j.neuropharm.2023.109826. Epub 2023 Dec 20. Neuropharmacology. 2024. PMID: 38135034
This network activity is especially efficient in the central and peripheral nervous systems, driven by secretion of the (co)transmitter ATP (including its enzymatic degradation products ADP, AMP, and adenosine), as well as ATP/UTP (including UDP) released from the c …
This network activity is especially efficient in the central and peripheral nervous systems, driven by secretion of the (co)transm …
Astroglia-Derived ATP Modulates CNS Neuronal Circuits.
Illes P, Burnstock G, Tang Y. Illes P, et al. Trends Neurosci. 2019 Dec;42(12):885-898. doi: 10.1016/j.tins.2019.09.006. Epub 2019 Nov 5. Trends Neurosci. 2019. PMID: 31704181 Review.
It is broadly recognized that ATP not only supports energy storage within cells but is also a transmitter/signaling molecule that serves intercellular communication. Whereas the fast (co)transmitter function of ATP in the peripheral nervous system has been convincin …
It is broadly recognized that ATP not only supports energy storage within cells but is also a transmitter/signaling molecule that serves int …
D-Serine, the Shape-Shifting NMDA Receptor Co-agonist.
Coyle JT, Balu D, Wolosker H. Coyle JT, et al. Neurochem Res. 2020 Jun;45(6):1344-1353. doi: 10.1007/s11064-020-03014-1. Epub 2020 Mar 18. Neurochem Res. 2020. PMID: 32189130 Free PMC article. Review.
The amino acid D-serine over the last 25 years has "shape-shifted" into several identities: a purported glial transmitter activating N-methyl-D-aspartate receptors (NMDARs), a co-transmitter concentrated in excitatory glutamatergic neurons, an autocrine that is rele …
The amino acid D-serine over the last 25 years has "shape-shifted" into several identities: a purported glial transmitter activating N-methy …
Cotransmission.
Burnstock G. Burnstock G. Curr Opin Pharmacol. 2004 Feb;4(1):47-52. doi: 10.1016/j.coph.2003.08.001. Curr Opin Pharmacol. 2004. PMID: 15018838 Review.
ATP appears to be a primitive signalling molecule that has been retained as a cotransmitter in every nerve type in both peripheral and central nervous systems, although the relative role of ATP varies considerably in different species and pathological conditions. In the pa …
ATP appears to be a primitive signalling molecule that has been retained as a cotransmitter in every nerve type in both peripheral an …
Atypical neural messengers.
Barañano DE, Ferris CD, Snyder SH. Barañano DE, et al. Trends Neurosci. 2001 Feb;24(2):99-106. doi: 10.1016/s0166-2236(00)01716-1. Trends Neurosci. 2001. PMID: 11164940 Review.
In addition, zinc, stored together with glutamate in synaptic vesicles, appears to act as an 'antagonist' co-transmitter at the NMDA receptor, and although localized exclusively to glia, D-serine fulfills most neurotransmitter criteria as an endogenous ligand for th …
In addition, zinc, stored together with glutamate in synaptic vesicles, appears to act as an 'antagonist' co-transmitter at th …
Purinergic Signaling in the Vertebrate Olfactory System.
Rotermund N, Schulz K, Hirnet D, Lohr C. Rotermund N, et al. Front Cell Neurosci. 2019 Apr 16;13:112. doi: 10.3389/fncel.2019.00112. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31057369 Free PMC article. Review.
Adenosine 5'-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain. ATP itself, as well as its breakdown products ADP and adenosine are involved in synaptic transmission and plasticity, neuron-glia communication and neural development. ...
Adenosine 5'-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain. ATP itself, as well as its breakdown …
Serine Racemase Expression by Striatal Neurons.
Takagi S, Puhl MD, Anderson T, Balu DT, Coyle JT. Takagi S, et al. Cell Mol Neurobiol. 2022 Jan;42(1):279-289. doi: 10.1007/s10571-020-00880-9. Epub 2020 May 22. Cell Mol Neurobiol. 2022. PMID: 32445040 Free PMC article.
Results in this study suggest that SR in striatal GABAergic neurons is synthesizing D-serine, not as a glutamatergic co-transmitter, but rather as an autocrine whereby the GABAergic neurons control the excitability of their NMDARs by determining the availability of …
Results in this study suggest that SR in striatal GABAergic neurons is synthesizing D-serine, not as a glutamatergic co-transmitte …
Functional Implications of Neurotransmitter Segregation.
Cifuentes F, Morales MA. Cifuentes F, et al. Front Neural Circuits. 2021 Oct 13;15:738516. doi: 10.3389/fncir.2021.738516. eCollection 2021. Front Neural Circuits. 2021. PMID: 34720888 Free PMC article. Review.
Adrenaline and hypertension.
Brown MJ, Dollery CT. Brown MJ, et al. Clin Exp Hypertens A. 1984;6(1-2):539-49. doi: 10.3109/10641968409062582. Clin Exp Hypertens A. 1984. PMID: 6141856
Recent pharmacological studies have suggested that adrenaline acts on a presynaptic beta-receptor on sympathetic nerve endings to facilitate noradrenaline release, and it has been proposed that adrenaline re-released from these nerve endings is therefore a functionally important …
Recent pharmacological studies have suggested that adrenaline acts on a presynaptic beta-receptor on sympathetic nerve endings to facilitate …
1,046 results