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108 results

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Page 1
Coptis japonica root extract induces apoptosis through caspase3 activation in SNU-668 human gastric cancer cells.
Park HJ, Kim YJ, Leem K, Park SJ, Seo JC, Kim HK, Chung JH. Park HJ, et al. Phytother Res. 2005 Mar;19(3):189-92. doi: 10.1002/ptr.1539. Phytother Res. 2005. PMID: 15934021
The cytotoxicity of Coptis japonica at 100 microg/ml (methanol extract) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was 13.89 +/- 1.91% of control value. ...Furthermore, the activity of caspase3 was significantly increased by Copti …
The cytotoxicity of Coptis japonica at 100 microg/ml (methanol extract) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliu …
Coptis japonica Makino extract suppresses angiogenesis through regulation of cell cycle-related proteins.
Kim SH, Kim EC, Kim WJ, Lee MH, Kim SY, Kim TJ. Kim SH, et al. Biosci Biotechnol Biochem. 2016 Jun;80(6):1095-106. doi: 10.1080/09168451.2016.1148574. Epub 2016 Feb 29. Biosci Biotechnol Biochem. 2016. PMID: 26924430
In this study, we characterized the anti-angiogenic effects of Coptis japonica Makino extract (CJME) and its mechanism of action. ...
In this study, we characterized the anti-angiogenic effects of Coptis japonica Makino extract (CJME) and its mechanism of acti …
Isoquinoline alkaloids from Coptis japonica stimulate the myoblast differentiation via p38 MAP-kinase and Akt signaling pathway.
Lee H, Tuong LT, Jeong JH, Lee SJ, Bae GU, Ryu JH. Lee H, et al. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1401-1404. doi: 10.1016/j.bmcl.2017.02.003. Epub 2017 Feb 4. Bioorg Med Chem Lett. 2017. PMID: 28228365
To overcome the muscle atrophy, such as cachexia and sarcopenia, we tried to find myogenic agents from medicinal plants. From myogenic extract of Coptis japonica, we purified six isoquinoline alkaloids and evaluated their effects on transactivation of myoD and MHC e …
To overcome the muscle atrophy, such as cachexia and sarcopenia, we tried to find myogenic agents from medicinal plants. From myogenic extra …
Morphological and genetic differences between Coptis japonica var. anemonifolia H. Ohba and Coptis japonica var. major Satake in Hokuriku area.
Kitamura M, Ando H, Sasaki Y. Kitamura M, et al. J Nat Med. 2018 Mar;72(2):514-522. doi: 10.1007/s11418-018-1179-9. Epub 2018 Feb 12. J Nat Med. 2018. PMID: 29435791
Coptis japonica is widely distributed in Japan, and its dried rhizome is a source of the domestic herbal medicine Coptidis Rhizoma ( Oren). There are three varieties of C. japonica, two of which, namely, C. japonica var. anemonifolia and C. japonica var. major, are …
Coptis japonica is widely distributed in Japan, and its dried rhizome is a source of the domestic herbal medicine Coptidis Rhi …
Scientometric Analysis of Medicinal and Edible Plant Coptis.
Huang Z, Hou Z, Liu F, Zhang M, Hu W, Xu S. Huang Z, et al. Front Pharmacol. 2021 Aug 12;12:725162. doi: 10.3389/fphar.2021.725162. eCollection 2021. Front Pharmacol. 2021. PMID: 34456737 Free PMC article.
A keyword analysis further revealed that the research hotspots were primarily concentrated in three fields of research involving berberine, Coptis chinensis Franch, and Coptis japonica (Thunb) Makino. Oxidative stress, rat plasma (for the determination of plasma alk …
A keyword analysis further revealed that the research hotspots were primarily concentrated in three fields of research involving berberine, …
Characterization of Burkholderia sp. strain CJ1, a newly isolated berberine-degrading bacterium from rhizosphere of Coptis japonica.
Yoshida H, Takeda H, Wakana D, Hosoe T. Yoshida H, et al. Biosci Biotechnol Biochem. 2020 Jun;84(6):1299-1302. doi: 10.1080/09168451.2020.1721264. Epub 2020 Jan 27. Biosci Biotechnol Biochem. 2020. PMID: 31985355
Burkholderia sp. strain CJ1 was newly isolated as berberine (BBR) degrading bacteria from rhizosphere of Coptis japonica. CJ1 had the ability to utilize BBR as the sole carbon source and revealed that BBR metabolism via 11-hydroxylation and demethylenation pathway. …
Burkholderia sp. strain CJ1 was newly isolated as berberine (BBR) degrading bacteria from rhizosphere of Coptis japonica. CJ1 …
Characterization of Coptis japonica CjABCB2, an ATP-binding cassette protein involved in alkaloid transport.
Shitan N, Dalmas F, Dan K, Kato N, Ueda K, Sato F, Forestier C, Yazaki K. Shitan N, et al. Phytochemistry. 2013 Jul;91:109-16. doi: 10.1016/j.phytochem.2012.02.012. Epub 2012 Mar 10. Phytochemistry. 2013. PMID: 22410351 Free article.
However, knowledge of the membrane transport mechanism of alkaloids is still limited. Coptis japonica, a perennial Ranunculaceous plant, produces the benzylisoquinoline alkaloid berberine. ...
However, knowledge of the membrane transport mechanism of alkaloids is still limited. Coptis japonica, a perennial Ranunculace …
Functional analysis of norcoclaurine synthase in Coptis japonica.
Minami H, Dubouzet E, Iwasa K, Sato F. Minami H, et al. J Biol Chem. 2007 Mar 2;282(9):6274-82. doi: 10.1074/jbc.M608933200. Epub 2007 Jan 4. J Biol Chem. 2007. PMID: 17204481 Free article.
Although cDNA of the pathogenesis-related (PR) 10 family, the translation product of which catalyzes NCS reaction, has been isolated from Thalictrum flavum, its detailed enzymological properties have not yet been characterized. We report here that a distinct cDNA isolated from …
Although cDNA of the pathogenesis-related (PR) 10 family, the translation product of which catalyzes NCS reaction, has been isolated from Th …
Galactinol synthase gene of Coptis japonica is involved in berberine tolerance.
Takanashi K, Shitan N, Sugiyama A, Kamimoto Y, Hamamoto M, Iwaki T, Takegawa K, Yazaki K. Takanashi K, et al. Biosci Biotechnol Biochem. 2008 Feb;72(2):398-405. doi: 10.1271/bbb.70495. Epub 2008 Feb 7. Biosci Biotechnol Biochem. 2008. PMID: 18256493 Free article.
In order to clarify the detoxification mechanism of alkaloids, we used cultured cells of Coptis japonica, which are capable of producing a yellow benzylisoquinoline alkaloid, berberine, and accumulate it in the vacuole. ...
In order to clarify the detoxification mechanism of alkaloids, we used cultured cells of Coptis japonica, which are capable of …
108 results