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Page 1
The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update.
Maurer M, Magerl M, Betschel S, Aberer W, Ansotegui IJ, Aygören-Pürsün E, Banerji A, Bara NA, Boccon-Gibod I, Bork K, Bouillet L, Boysen HB, Brodszki N, Busse PJ, Bygum A, Caballero T, Cancian M, Castaldo A, Cohn DM, Csuka D, Farkas H, Gompels M, Gower R, Grumach AS, Guidos-Fogelbach G, Hide M, Kang HR, Kaplan AP, Katelaris C, Kiani-Alikhan S, Lei WT, Lockey R, Longhurst H, Lumry WR, MacGinnitie A, Malbran A, Martinez Saguer I, Matta JJ, Nast A, Nguyen D, Nieto-Martinez SA, Pawankar R, Peter J, Porebski G, Prior N, Reshef A, Riedl M, Ritchie B, Rafique Sheikh F, Smith WB, Spaeth PJ, Stobiecki M, Toubi E, Varga LA, Weller K, Zanichelli A, Zhi Y, Zuraw B, Craig T. Maurer M, et al. Allergy. 2022 Jul;77(7):1961-1990. doi: 10.1111/all.15214. Epub 2022 Feb 3. Allergy. 2022. PMID: 35006617
The goal of these recommendations and guideline is to help physicians and their patients in making rational decisions in the management of HAE with deficient C1 inhibitor (type 1) and HAE with dysfunctional C1 inhibitor (type 2), by providing guidance …
The goal of these recommendations and guideline is to help physicians and their patients in making rational decisions in the management of H …
Treatment of Hereditary Angioedema.
Caballero T. Caballero T. J Investig Allergol Clin Immunol. 2021 Feb;31(1):1-16. doi: 10.18176/jiaci.0653. J Investig Allergol Clin Immunol. 2021. PMID: 33602658 Free article. Review.
Hereditary angioedema due to C1-esterase inhibitor deficiency (C1-INH-HAE) is a rare autosomal dominant disease. ...Purified plasma-derived human C1 esterase inhibitor concentrate is the treatment of choice for short-term prophylaxis. ...
Hereditary angioedema due to C1-esterase inhibitor deficiency (C1-INH-HAE) is a rare autosomal dominant disease. ...Pur …
Hereditary Angioedema.
Wilkerson RG, Moellman JJ. Wilkerson RG, et al. Immunol Allergy Clin North Am. 2023 Aug;43(3):533-552. doi: 10.1016/j.iac.2022.10.012. Immunol Allergy Clin North Am. 2023. PMID: 37394258 Review.
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder that usual results from a decreased level of functional C1-INH and clinically manifests with intermittent attacks of swelling of the subcutaneous tissue or submucosal layers of the respiratory or gas …
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder that usual results from a decreased level of functional C1- …
Hereditary Angioedema.
Busse PJ, Christiansen SC. Busse PJ, et al. N Engl J Med. 2020 Mar 19;382(12):1136-1148. doi: 10.1056/NEJMra1808012. N Engl J Med. 2020. PMID: 32187470 Review. No abstract available.
Isolated angioedema: A review of classification and update on management.
Kesh S, Bernstein JA. Kesh S, et al. Ann Allergy Asthma Immunol. 2022 Dec;129(6):692-702. doi: 10.1016/j.anai.2022.08.003. Epub 2022 Aug 19. Ann Allergy Asthma Immunol. 2022. PMID: 35988876 Review.
RESULTS: Herein, a case-based approach is presented for discussing the major types of angioedema, including the following: hereditary angioedema types I and II and normal complement, acquired angioedema, angiotensin-converting enzyme-induced angioedema, and histaminergic a …
RESULTS: Herein, a case-based approach is presented for discussing the major types of angioedema, including the following: hereditary angioe …
Interventions for the long-term prevention of hereditary angioedema attacks.
Beard N, Frese M, Smertina E, Mere P, Katelaris C, Mills K. Beard N, et al. Cochrane Database Syst Rev. 2022 Nov 3;11(11):CD013403. doi: 10.1002/14651858.CD013403.pub2. Cochrane Database Syst Rev. 2022. PMID: 36326435 Free PMC article. Review.
People with Type I HAE (approximately 80% of all HAE cases) have insufficient amounts of C1 esterase inhibitor (C1-INH) protein; people with Type II HAE (approximately 20% of all cases) may have normal C1-INH concentrations, but, due to genetic …
People with Type I HAE (approximately 80% of all HAE cases) have insufficient amounts of C1 esterase inhibitor (C1-INH) …
C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation.
Beinrohr L, Dobó J, Závodszky P, Gál P. Beinrohr L, et al. Trends Mol Med. 2008 Dec;14(12):511-21. doi: 10.1016/j.molmed.2008.09.009. Epub 2008 Nov 1. Trends Mol Med. 2008. PMID: 18977695 Review.
The associated proteases (C1r, C1s, MASP-1 and MASP-2) then activate the complement system. The serpin C1-inhibitor (C1-inh) blocks activity of all these complexes and has been successfully used in models of disease. ...Here, we propose an approach in …
The associated proteases (C1r, C1s, MASP-1 and MASP-2) then activate the complement system. The serpin C1-inhibitor ( …
Potential Roles for C1 Inhibitor in Transplantation.
Berger M, Baldwin WM 3rd, Jordan SC. Berger M, et al. Transplantation. 2016 Jul;100(7):1415-24. doi: 10.1097/TP.0000000000000995. Transplantation. 2016. PMID: 26599489 Free PMC article. Review.
The latter is increasingly recognized as a major cause of late graft loss, for which we have few effective therapies. C1 inhibitor (C1-INH) regulates several pathways which contribute to both acute and chronic graft injuries. ...Studies with C1-INH in …
The latter is increasingly recognized as a major cause of late graft loss, for which we have few effective therapies. C1 inhibitor
Binding of human complement C1 sterase inhibitor to Leptospira spp.
Breda LCD, Vasconcellos SA, de Moraes Vasconcelos D, Isaac L. Breda LCD, et al. Immunobiology. 2018 Feb;223(2):183-190. doi: 10.1016/j.imbio.2017.10.027. Epub 2017 Oct 13. Immunobiology. 2018. PMID: 29107384
Pathogenic Leptospira interact with Complement Regulators such as Factor H, C4b binding protein and Vitronectin avoiding Complement activation and killing by Alternative and Classical Pathways. One important regulator is C1-inhibitor (C1INH) tha …
Pathogenic Leptospira interact with Complement Regulators such as Factor H, C4b binding protein and Vitronectin avoiding Co
C1-inhibitor: more than a serine protease inhibitor.
Zeerleder S. Zeerleder S. Semin Thromb Hemost. 2011 Jun;37(4):362-74. doi: 10.1055/s-0031-1276585. Epub 2011 Jul 30. Semin Thromb Hemost. 2011. PMID: 21805442 Review.
C1-inhibitor (C1-inh) is a crucial regulator of the activation of plasmatic cascade systems involved in inflammation contributing to the homeostasis in the generation of proinflammatory mediators. ...Recent publications, however, suggest that the anti-inflamm
C1-inhibitor (C1-inh) is a crucial regulator of the activation of plasmatic cascade systems involved in inflammation co
2,086 results