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Items: 1 to 20 of 172

1.

The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home.

van Loosdregt J, Coffer PJ.

J Immunol. 2018 Oct 15;201(8):2193-2200. doi: 10.4049/jimmunol.1800633. Review.

PMID:
30301837
2.

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.

Petrelli A, Mijnheer G, van Konijnenburg DPH, van der Wal MM, Giovannone B, Mocholi E, Vazirpanah N, Broen JC, Hijnen D, Oldenburg B, Coffer PJ, Vastert SJ, Prakken BJ, Spierings E, Pandit A, Mokry M, van Wijk F.

J Clin Invest. 2018 Oct 1;128(10):4669-4681. doi: 10.1172/JCI96107. Epub 2018 Aug 2.

3.

STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells.

Ribeiro D, Melão A, van Boxtel R, Santos CI, Silva A, Silva MC, Cardoso BA, Coffer PJ, Barata JT.

Blood Adv. 2018 Sep 11;2(17):2199-2213. doi: 10.1182/bloodadvances.2018021063.

4.

Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis.

Zaiss DMW, Coffer PJ.

Nat Rev Immunol. 2018 Sep 3. doi: 10.1038/s41577-018-0048-9. [Epub ahead of print] Review.

PMID:
30177790
5.

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy.

Peeters JGC, Picavet LW, Coenen SGJM, Mauthe M, Vervoort SJ, Mocholi E, de Heus C, Klumperman J, Vastert SJ, Reggiori F, Coffer PJ, Mokry M, van Loosdregt J.

Autophagy. 2018 Sep 11:1-15. doi: 10.1080/15548627.2018.1509608. [Epub ahead of print]

PMID:
30153076
6.

SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

Vervoort SJ, Lourenço AR, Tufegdzic Vidakovic A, Mocholi E, Sandoval JL, Rueda OM, Frederiks C, Pals C, Peeters JGC, Caldas C, Bruna A, Coffer PJ.

Nucleic Acids Res. 2018 Oct 12;46(18):9578-9590. doi: 10.1093/nar/gky755.

PMID:
30137431
7.

Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy.

Mocholi E, Dowling SD, Botbol Y, Gruber RC, Ray AK, Vastert S, Shafit-Zagardo B, Coffer PJ, Macian F.

Cell Rep. 2018 Jul 31;24(5):1136-1150. doi: 10.1016/j.celrep.2018.06.065.

8.

Forkhead box protein P1, a key player in neuronal development?

Braccioli L, Nijboer CH, Coffer PJ.

Neural Regen Res. 2018 May;13(5):801-802. doi: 10.4103/1673-5374.232467. No abstract available.

9.

Megakaryocyte lineage development is controlled by modulation of protein acetylation.

Bartels M, Govers A, Polak R, Vervoort S, van Boxtel R, Pals C, Bierings M, van Solinge W, Egberts T, Nieuwenhuis E, Mokry M, Coffer PJ.

PLoS One. 2018 Apr 26;13(4):e0196400. doi: 10.1371/journal.pone.0196400. eCollection 2018.

10.

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency.

van Rijn JM, Ardy RC, Kuloğlu Z, Härter B, van Haaften-Visser DY, van der Doef HPJ, van Hoesel M, Kansu A, van Vugt AHM, Thian M, Kokke FTM, Krolo A, Başaran MK, Kaya NG, Aksu AÜ, Dalgıç B, Ozcay F, Baris Z, Kain R, Stigter ECA, Lichtenbelt KD, Massink MPG, Duran KJ, Verheij JBGM, Lugtenberg D, Nikkels PGJ, Brouwer HGF, Verkade HJ, Scheenstra R, Spee B, Nieuwenhuis EES, Coffer PJ, Janecke AR, van Haaften G, Houwen RHJ, Müller T, Middendorp S, Boztug K.

Gastroenterology. 2018 Jul;155(1):130-143.e15. doi: 10.1053/j.gastro.2018.03.040. Epub 2018 Mar 29.

11.

Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro.

Vonk LA, van Dooremalen SFJ, Liv N, Klumperman J, Coffer PJ, Saris DBF, Lorenowicz MJ.

Theranostics. 2018 Jan 1;8(4):906-920. doi: 10.7150/thno.20746. eCollection 2018.

12.

FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression.

Braccioli L, Vervoort SJ, Adolfs Y, Heijnen CJ, Basak O, Pasterkamp RJ, Nijboer CH, Coffer PJ.

Stem Cell Reports. 2017 Nov 14;9(5):1530-1545. doi: 10.1016/j.stemcr.2017.10.012.

13.

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.

Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM.

Immunity. 2017 Oct 17;47(4):710-722.e6. doi: 10.1016/j.immuni.2017.09.013.

14.

SOX4: Joining the Master Regulators of Epithelial-to-Mesenchymal Transition?

Lourenço AR, Coffer PJ.

Trends Cancer. 2017 Aug;3(8):571-582. doi: 10.1016/j.trecan.2017.06.002. Epub 2017 Jul 8. Review.

PMID:
28780934
15.

Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia.

Folkerts H, Hilgendorf S, Wierenga ATJ, Jaques J, Mulder AB, Coffer PJ, Schuringa JJ, Vellenga E.

Cell Death Dis. 2017 Jul 13;8(7):e2927. doi: 10.1038/cddis.2017.317.

16.

A tumor suppressor role for C/EBPα in solid tumors: more than fat and blood.

Lourenço AR, Coffer PJ.

Oncogene. 2017 Sep 14;36(37):5221-5230. doi: 10.1038/onc.2017.151. Epub 2017 May 15. Review.

PMID:
28504718
17.

Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.

van Haaften-Visser DY, Harakalova M, Mocholi E, van Montfrans JM, Elkadri A, Rieter E, Fiedler K, van Hasselt PM, Triffaux EMM, van Haelst MM, Nijman IJ, Kloosterman WP, Nieuwenhuis EES, Muise AM, Cuppen E, Houwen RHJ, Coffer PJ.

J Biol Chem. 2017 May 12;292(19):7904-7920. doi: 10.1074/jbc.M116.772038. Epub 2017 Mar 16.

18.

Delayed administration of neural stem cells after hypoxia-ischemia reduces sensorimotor deficits, cerebral lesion size, and neuroinflammation in neonatal mice.

Braccioli L, Heijnen CJ, Coffer PJ, Nijboer CH.

Pediatr Res. 2017 Jan;81(1-1):127-135. doi: 10.1038/pr.2016.172. Epub 2016 Sep 15.

PMID:
27632779
19.

Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation.

Gómez-Puerto MC, Verhagen LP, Braat AK, Lam EW, Coffer PJ, Lorenowicz MJ.

Autophagy. 2016 Oct 2;12(10):1804-1816. Epub 2016 Aug 17.

20.

Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34(+) Hematopoietic Stem-Progenitor Cells.

Gomez-Puerto MC, Folkerts H, Wierenga AT, Schepers K, Schuringa JJ, Coffer PJ, Vellenga E.

Stem Cells. 2016 Jun;34(6):1651-63. doi: 10.1002/stem.2347. Epub 2016 Mar 28.

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