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Page 1
Development of highly efficient whole-cell catalysts of cis-epoxysuccinic acid hydrolase by surface display.
Zhou R, Dong S, Feng Y, Cui Q, Xuan J. Zhou R, et al. Bioresour Bioprocess. 2022 Aug 29;9(1):92. doi: 10.1186/s40643-022-00584-6. Bioresour Bioprocess. 2022. PMID: 38647583 Free PMC article.
Bacterial cis-epoxysuccinic acid hydrolases (CESHs) are intracellular enzymes used in the industrial production of enantiomeric tartaric acids. ...Thereby, an efficient whole-cell CESH[L] biocatalyst was developed in this study, which solves the cell p …
Bacterial cis-epoxysuccinic acid hydrolases (CESHs) are intracellular enzymes used in the industrial production of enan …
Efficiency and stability enhancement of cis-epoxysuccinic acid hydrolase by fusion with a carbohydrate binding module and immobilization onto cellulose.
Wang S, Cui GZ, Song XF, Feng Y, Cui Q. Wang S, et al. Appl Biochem Biotechnol. 2012 Oct;168(3):708-17. doi: 10.1007/s12010-012-9811-8. Epub 2012 Jul 29. Appl Biochem Biotechnol. 2012. PMID: 22843080
Cis-epoxysuccinic acid hydrolase (CESH) is an enzyme that catalyzes cis-epoxysuccinic acid to produce enantiomeric L(+)-tartaric acid. The production of tartaric acid by using CESH would be valuable in the chemical industry
Cis-epoxysuccinic acid hydrolase (CESH) is an enzyme that catalyzes cis-epoxysuccinic acid to prod
Optimization of culture conditions for production of cis-epoxysuccinic acid hydrolase using response surface methodology.
Li X, Xu T, Ma X, Guo K, Kai L, Zhao Y, Jia X, Ma Y. Li X, et al. Bioresour Technol. 2008 Sep;99(13):5391-6. doi: 10.1016/j.biortech.2007.11.017. Epub 2008 Feb 20. Bioresour Technol. 2008. PMID: 18083551
Yeast extract, cis-epoxysuccinic acid and KH(2)PO(4) had significant influences on cis-epoxysuccinic acid hydrolase production and their concentrations were further optimized using central composite design and response surface analysis. A …
Yeast extract, cis-epoxysuccinic acid and KH(2)PO(4) had significant influences on cis-epoxysuccinic a
Purification and characterization of a cis-epoxysuccinic acid hydrolase from Nocardia tartaricans CAS-52, and expression in Escherichia coli.
Wang Z, Wang Y, Su Z. Wang Z, et al. Appl Microbiol Biotechnol. 2013 Mar;97(6):2433-41. doi: 10.1007/s00253-012-4102-4. Epub 2012 May 3. Appl Microbiol Biotechnol. 2013. PMID: 22552902
A highly enantioselective cis-epoxysuccinic acid hydrolase from Nocardia tartaricans was purified to electrophoretic homogeneity. ...The enzyme was activated by Ni(2+) and Al(3+), while strongly inhibited by Fe(3+), Fe(2+), Cu(2+), and Ag(+). The cis- …
A highly enantioselective cis-epoxysuccinic acid hydrolase from Nocardia tartaricans was purified to electrophoretic ho …
Purification and characterization of a cis-epoxysuccinic acid hydrolase from Bordetella sp. strain 1-3.
Li X, Xu T, Lu H, Ma X, Kai L, Guo K, Zhao Y. Li X, et al. Protein Expr Purif. 2010 Jan;69(1):16-20. doi: 10.1016/j.pep.2009.09.018. Epub 2009 Oct 1. Protein Expr Purif. 2010. PMID: 19800407
Purification of a cis-epoxysuccinic acid hydrolase was achieved by ammonium sulfate precipitation, ionic exchange chromatography, hydrophobic interaction chromatography followed by size-exclusion chromatography. ...Results of inductively coupled plasma mass s …
Purification of a cis-epoxysuccinic acid hydrolase was achieved by ammonium sulfate precipitation, ionic exchange chrom …
Isolation and characterization of a new bacterium capable of biotransforming cis -epoxysuccinic acid to D(-) -tartaric acid.
Li X, Ma X, Zhao Y, Jia X, Kai L, Guo K, Zhao W. Li X, et al. FEMS Microbiol Lett. 2007 Feb;267(2):214-20. doi: 10.1111/j.1574-6968.2006.00552.x. Epub 2006 Dec 8. FEMS Microbiol Lett. 2007. PMID: 17166227
A bacterial strain 1-3 capable of enantioselectively hydrolyzing cis-epoxysuccinic acid to D(-)-tartaric acid was isolated from soil. Phenotypic characteristics, Biolog GN test and phylogenetic analysis of strain 1-3 indicated that it belongs to the ge …
A bacterial strain 1-3 capable of enantioselectively hydrolyzing cis-epoxysuccinic acid to D(-)-tartaric acid wa …
High yield recombinant expression, characterization and homology modeling of two types of cis-epoxysuccinic acid hydrolases.
Cui GZ, Wang S, Li Y, Tian YJ, Feng Y, Cui Q. Cui GZ, et al. Protein J. 2012 Jun;31(5):432-8. doi: 10.1007/s10930-012-9418-5. Protein J. 2012. PMID: 22592448
The cis-epoxysuccinate hydrolases (CESHs), members of epoxide hydrolase, catalyze cis-epoxysuccinic acid hydrolysis to form D: (-)-tartaric acid or L: (+)-tartaric acid which are important chemicals with broad scientific and industrial applicati …
The cis-epoxysuccinate hydrolases (CESHs), members of epoxide hydrolase, catalyze cis-epoxysuccinic acid hydrolysis to …
Identification and pharmacological characterization of succinate receptor agonists.
Geubelle P, Gilissen J, Dilly S, Poma L, Dupuis N, Laschet C, Abboud D, Inoue A, Jouret F, Pirotte B, Hanson J. Geubelle P, et al. Br J Pharmacol. 2017 May;174(9):796-808. doi: 10.1111/bph.13738. Epub 2017 Mar 10. Br J Pharmacol. 2017. PMID: 28160606 Free PMC article.
The in vivo effects of activating succinate receptors with these new agonists was evaluated on rat BP. KEY RESULTS: We identified cis-epoxysuccinic acid and cis-1,2-cyclopropanedicarboxylic acid as agonists with an efficacy similar to that of succinic …
The in vivo effects of activating succinate receptors with these new agonists was evaluated on rat BP. KEY RESULTS: We identified cis
From infinite one-dimensional helix to discrete Cu(II)15 cluster along with in situ S(N)2 ring-cleavage of cis-epoxysuccinic acid: pH-controlled assemblies, crystal structures, and properties.
Fang SM, Zhang Q, Hu M, Sañudo EC, Du M, Liu CS. Fang SM, et al. Inorg Chem. 2010 Oct 18;49(20):9617-26. doi: 10.1021/ic101278w. Inorg Chem. 2010. PMID: 20853877
Two Cu(II) coordination complexes {[Cu(ces)(H(2)O)(2)](H(2)O)(0.5)}(n) (1) and [Cu(15)(dhs)(6)(OH)(6)(H(2)O)(10)](H(2)O)(20) (2) have been synthesized from cis-epoxysuccinic acid (cis-H(2)ces) and Cu(II) perchlorate under different pH conditions (ces = cis-ep …
Two Cu(II) coordination complexes {[Cu(ces)(H(2)O)(2)](H(2)O)(0.5)}(n) (1) and [Cu(15)(dhs)(6)(OH)(6)(H(2)O)(10)](H(2)O)(20) (2) have been s …
Isolation of Penicillium expansum WH-3 for the production of L(+)-tartaric acid.
Bao WN, Chen Y, Liao HX, Chen H, Liu SW, Liu Y. Bao WN, et al. J Zhejiang Univ Sci B. 2020 Oct.;21(10):835-840. doi: 10.1631/jzus.B2000269. J Zhejiang Univ Sci B. 2020. PMID: 33043648 Free PMC article.
The L(+)-form of tartaric acid (L(+)-TA) exists extensively in nature, and is widely used in the food, chemical, textile, building, and pharmaceutical industries (Su et al., 2001). The main method for L(+)-TA production is microbial transformation by cis-epoxysuccinate hyd …
The L(+)-form of tartaric acid (L(+)-TA) exists extensively in nature, and is widely used in the food, chemical, textile, building, a …
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