Identification and pharmacological characterization of succinate receptor agonists.
Geubelle P, Gilissen J, Dilly S, Poma L, Dupuis N, Laschet C, Abboud D, Inoue A, Jouret F, Pirotte B, Hanson J.
Geubelle P, et al.
Br J Pharmacol. 2017 May;174(9):796-808. doi: 10.1111/bph.13738. Epub 2017 Mar 10.
Br J Pharmacol. 2017.
PMID: 28160606
Free PMC article.
The in vivo effects of activating succinate receptors with these new agonists was evaluated on rat BP. KEY RESULTS: We identified cis-epoxysuccinic acid and cis-1,2-cyclopropanedicarboxylic acid as agonists with an efficacy similar to that of succinic …
The in vivo effects of activating succinate receptors with these new agonists was evaluated on rat BP. KEY RESULTS: We identified cis …