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Items: 1 to 20 of 57


Human macrophages survive and adopt activated genotypes in living zebrafish.

Paul CD, Devine A, Bishop K, Xu Q, Wulftange WJ, Burr H, Daly KM, Lewis C, Green DS, Staunton JR, Choksi S, Liu ZG, Sood R, Tanner K.

Sci Rep. 2019 Feb 11;9(1):1759. doi: 10.1038/s41598-018-38186-y.


Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis.

Jiao D, Cai Z, Choksi S, Ma D, Choe M, Kwon HJ, Baik JY, Rowan BG, Liu C, Liu ZG.

Cell Res. 2018 Aug;28(8):868-870. doi: 10.1038/s41422-018-0058-y. Epub 2018 Jun 25. No abstract available.


Switching from TNF-induced inflammation to death signaling.

Xu Q, Choksi S, Liu Z.

Mol Cell Oncol. 2017 Nov 30;5(1):e1392402. doi: 10.1080/23723556.2017.1392402. eCollection 2018.


Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.

Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G 3rd, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF.

Dev Cell. 2017 Dec 18;43(6):744-762.e11. doi: 10.1016/j.devcel.2017.11.014.


The cytoplasmic nuclear receptor RARĪ³ controls RIP1 initiated cell death when cIAP activity is inhibited.

Xu Q, Jitkaew S, Choksi S, Kadigamuwa C, Qu J, Choe M, Jang J, Liu C, Liu ZG.

Nat Commun. 2017 Sep 4;8(1):425. doi: 10.1038/s41467-017-00496-6.


Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling.

Shen H, Yu X, Yang F, Zhang Z, Shen J, Sun J, Choksi S, Jitkaew S, Shu Y.

PLoS Genet. 2016 Aug 19;12(8):e1006244. doi: 10.1371/journal.pgen.1006244. eCollection 2016 Aug.


NADPH Oxidases Are Essential for Macrophage Differentiation.

Xu Q, Choksi S, Qu J, Jang J, Choe M, Banfi B, Engelhardt JF, Liu ZG.

J Biol Chem. 2016 Sep 16;291(38):20030-41. doi: 10.1074/jbc.M116.731216. Epub 2016 Aug 3.


Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration.

Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang XM, Liu ZG.

Cell Res. 2016 Aug;26(8):886-900. doi: 10.1038/cr.2016.87. Epub 2016 Jul 22.


Mutations in CCDC11, which encodes a coiled-coil containing ciliary protein, causes situs inversus due to dysmotility of monocilia in the left-right organizer.

Narasimhan V, Hjeij R, Vij S, Loges NT, Wallmeier J, Koerner-Rettberg C, Werner C, Thamilselvam SK, Boey A, Choksi SP, Pennekamp P, Roy S, Omran H.

Hum Mutat. 2015 Mar;36(3):307-18. doi: 10.1002/humu.22738.


A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.

Lu H, Toh MT, Narasimhan V, Thamilselvam SK, Choksi SP, Roy S.

Dev Biol. 2015 Jan 15;397(2):225-36. doi: 10.1016/j.ydbio.2014.11.009. Epub 2014 Nov 20.


Systematic discovery of novel ciliary genes through functional genomics in the zebrafish.

Choksi SP, Babu D, Lau D, Yu X, Roy S.

Development. 2014 Sep;141(17):3410-9. doi: 10.1242/dev.108209.


Dissecting DR3 signaling.

Pobezinskaya YL, Liu Z, Choksi S.

Methods Mol Biol. 2014;1155:15-22. doi: 10.1007/978-1-4939-0669-7_2.


Switching on cilia: transcriptional networks regulating ciliogenesis.

Choksi SP, Lauter G, Swoboda P, Roy S.

Development. 2014 Apr;141(7):1427-41. doi: 10.1242/dev.074666. Review.


Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.

Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG.

Nat Cell Biol. 2014 Jan;16(1):55-65. doi: 10.1038/ncb2883. Epub 2013 Dec 8. Erratum in: Nat Cell Biol. 2014 Feb;16(2):200.


Butylated hydroxyanisole blocks the occurrence of tumor associated macrophages in tobacco smoke carcinogen-induced lung tumorigenesis.

Zhang Y, Choksi S, Liu ZG.

Cancers (Basel). 2013 Dec 4;5(4):1643-54. doi: 10.3390/cancers5041643.


ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages.

Zhang Y, Choksi S, Chen K, Pobezinskaya Y, Linnoila I, Liu ZG.

Cell Res. 2013 Jul;23(7):898-914. doi: 10.1038/cr.2013.75. Epub 2013 Jun 11.


Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.

Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5322-7. doi: 10.1073/pnas.1200012109. Epub 2012 Mar 15.


Induction of autophagy is essential for monocyte-macrophage differentiation.

Zhang Y, Morgan MJ, Chen K, Choksi S, Liu ZG.

Blood. 2012 Mar 22;119(12):2895-905. doi: 10.1182/blood-2011-08-372383. Epub 2012 Jan 5.


A HIF-1 target, ATIA, protects cells from apoptosis by modulating the mitochondrial thioredoxin, TRX2.

Choksi S, Lin Y, Pobezinskaya Y, Chen L, Park C, Morgan M, Li T, Jitkaew S, Cao X, Kim YS, Kim HS, Levitt P, Shih G, Birre M, Deng CX, Liu ZG.

Mol Cell. 2011 Jun 10;42(5):597-609. doi: 10.1016/j.molcel.2011.03.030.

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