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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1961 6
1962 4
1963 18
1964 14
1965 8
1966 24
1967 17
1968 13
1969 12
1970 13
1971 12
1972 16
1973 10
1974 12
1975 8
1976 16
1977 9
1978 21
1979 11
1980 9
1981 12
1982 12
1983 18
1984 16
1985 17
1986 15
1987 14
1988 20
1989 18
1990 19
1991 14
1992 5
1993 6
1994 7
1995 7
1996 3
1997 3
1998 1
2000 3
2001 1
2002 2
2003 1
2004 4
2005 1
2006 4
2007 3
2008 5
2009 1
2010 2
2011 3
2012 2
2013 1
2014 2
2016 1
2018 1
2021 2
2022 4
2023 4
2024 1

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507 results

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Page 1
The unapproved drug centrophenoxine (meclofenoxate) in cognitive enhancement dietary supplements.
Cohen PA, Avula B, Khan I. Cohen PA, et al. Clin Toxicol (Phila). 2022 Oct;60(10):1156-1158. doi: 10.1080/15563650.2022.2109485. Epub 2022 Aug 12. Clin Toxicol (Phila). 2022. PMID: 35959800
INTRODUCTION: Centrophenoxine (meclofenoxate) is prescribed in China and elsewhere to treat a variety of conditions including alcoholism and dementia, but the US Food and Drug Administration has not approved the drug for any indication. ...Consumers following the ma …
INTRODUCTION: Centrophenoxine (meclofenoxate) is prescribed in China and elsewhere to treat a variety of conditions including …
On the role of intracellular physicochemistry in quantitative gene expression during aging and the effect of centrophenoxine. A review.
Zs-Nagy I. Zs-Nagy I. Arch Gerontol Geriatr. 1989 Nov-Dec;9(3):215-29. doi: 10.1016/0167-4943(89)90042-3. Arch Gerontol Geriatr. 1989. PMID: 2517957 Review.
Increase of the dry mass content of cells and tissues is an obligatory process for maturation; however, later on it leads to aging. The known nootropic effects of centrophenoxine (CPH) can be interpreted on the basis of the OH. radical scavenger properties of dimethylamino …
Increase of the dry mass content of cells and tissues is an obligatory process for maturation; however, later on it leads to aging. The know …
Effects of centrophenoxine on cholinephosphotransferase activity in maternal and fetal guinea pig lung.
Stith IE, Nag S, Mukherjee S, Das SK. Stith IE, et al. Exp Lung Res. 1989 Jul;15(4):587-96. doi: 10.3109/01902148909069620. Exp Lung Res. 1989. PMID: 2548832
Cholinephosphotransferase activities of guinea pig lung mitochondria and microsomes are inhibited by centrophenoxine and one of its metabolites, p-chlorophenoxyacetate. 2-Dimethylaminoethanol, the second metabolite of centrophenoxine, has no inhibitory effect on the …
Cholinephosphotransferase activities of guinea pig lung mitochondria and microsomes are inhibited by centrophenoxine and one of its m …
Gerontopsychological studies using NAI ('Nurnberger Alters-Inventar') on patients with organic psychosyndrome (DSM III, Category 1) treated with centrophenoxine in a double blind, comparative, randomized clinical trial.
Pék G, Fülöp T, Zs-Nagy I. Pék G, et al. Arch Gerontol Geriatr. 1989 Jul;9(1):17-30. doi: 10.1016/0167-4943(89)90021-6. Arch Gerontol Geriatr. 1989. PMID: 2506844 Review.
This was then followed by a treatment for 8 weeks with the nootropic drug, centrophenoxine (CPH), the dose of which was 2 g/day distributed in 2 x 2 tablets of Helfergin500 (Promonta, Hamburg, FRG), or with placebo tablets of identical size, then the NAI test was repeated …
This was then followed by a treatment for 8 weeks with the nootropic drug, centrophenoxine (CPH), the dose of which was 2 g/day distr …
Lipofuscin.
Bourne GH. Bourne GH. Prog Brain Res. 1973;40(0):187-201. doi: 10.1016/S0079-6123(08)60687-1. Prog Brain Res. 1973. PMID: 4608154 Review. No abstract available.
Centrophenoxine improves chronic cerebral ischemia induced cognitive deficit and neuronal degeneration in rats.
Liao Y, Wang R, Tang XC. Liao Y, et al. Acta Pharmacol Sin. 2004 Dec;25(12):1590-6. Acta Pharmacol Sin. 2004. PMID: 15569402 Free article.
AIM: To study the effects of centrophenoxine (CPH, meclofenoxate) on chronic cerebral hypoperfusion induced deficits in rats. ...
AIM: To study the effects of centrophenoxine (CPH, meclofenoxate) on chronic cerebral hypoperfusion induced deficits in rats. …
Centrophenoxine: effects on aging mammalian brain.
Nandy K. Nandy K. J Am Geriatr Soc. 1978 Feb;26(2):74-81. doi: 10.1111/j.1532-5415.1978.tb02544.x. J Am Geriatr Soc. 1978. PMID: 342588
A study was made of the effects of centrophenoxine on the learning and memory of old mice. The results were correlated with changes in neuronal lipofuscin in the cerebral cortex and hippocampus. ...
A study was made of the effects of centrophenoxine on the learning and memory of old mice. The results were correlated with changes i …
Centrophenoxine-induced increase of beta-adrenoceptor density in brain cortex of old mice.
Viticchi C, Gentile S, Piantanelli L. Viticchi C, et al. Arch Gerontol Geriatr. 1984 May;3(1):77-82. doi: 10.1016/0167-4943(84)90017-7. Arch Gerontol Geriatr. 1984. PMID: 6331330
The influence of centrophenoxine treatment on beta-adrenoceptor density has been studied in the brain cortex of old mice. One group of 21-mth-old mice was injected intraperitoneally with 3.8 mg/day centrophenoxine daily for 5 days. A second group received the same d …
The influence of centrophenoxine treatment on beta-adrenoceptor density has been studied in the brain cortex of old mice. One group o …
Life extension.
Schneider EL, Reed JD Jr. Schneider EL, et al. N Engl J Med. 1985 May 2;312(18):1159-68. doi: 10.1056/NEJM198505023121805. N Engl J Med. 1985. PMID: 3157059 Review. No abstract available.
507 results