Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 28

1.

WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.

Wen J, Lee J, Malhotra A, Nahta R, Arnold AR, Buss MC, Brown BD, Maier C, Kenney AM, Remke M, Ramaswamy V, Taylor MD, Castellino RC.

Oncogene. 2016 Oct 20;35(42):5552-5564. doi: 10.1038/onc.2016.96. Epub 2016 Apr 18.

2.

PPM1D/WIP1 in medulloblastoma.

Akamandisa MP, Nahta R, Castellino RC.

Oncoscience. 2016 Sep 3;3(7-8):186-187. eCollection 2016. No abstract available.

3.

Successful Retreatment of a Child with a Refractory Brainstem Ganglioglioma with Vemurafenib.

Aguilera D, Janss A, Mazewski C, Castellino RC, Schniederjan M, Hayes L, Brahma B, Fogelgren L, MacDonald TJ.

Pediatr Blood Cancer. 2016 Mar;63(3):541-3. doi: 10.1002/pbc.25787. Epub 2015 Nov 18.

PMID:
26579623
4.

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondráček J, Raju J, Roman J, Wise JP Sr, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engström W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu Z.

Carcinogenesis. 2015 Jun;36 Suppl 1:S254-96. doi: 10.1093/carcin/bgv039. Review. Erratum in: Carcinogenesis. 2016 Mar;37(3):344.

5.

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

Nahta R, Al-Mulla F, Al-Temaimi R, Amedei A, Andrade-Vieira R, Bay SN, Brown DG, Calaf GM, Castellino RC, Cohen-Solal KA, Colacci A, Cruickshanks N, Dent P, Di Fiore R, Forte S, Goldberg GS, Hamid RA, Krishnan H, Laird DW, Lasfar A, Marignani PA, Memeo L, Mondello C, Naus CC, Ponce-Cusi R, Raju J, Roy D, Roy R, Ryan EP, Salem HK, Scovassi AI, Singh N, Vaccari M, Vento R, Vondráček J, Wade M, Woodrick J, Bisson WH.

Carcinogenesis. 2015 Jun;36 Suppl 1:S2-18. doi: 10.1093/carcin/bgv028. Review.

6.

Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.

Sanabria-Figueroa E, Donnelly SM, Foy KC, Buss MC, Castellino RC, Paplomata E, Taliaferro-Smith L, Kaumaya PT, Nahta R.

Mol Pharmacol. 2015 Feb;87(2):150-61. doi: 10.1124/mol.114.095380. Epub 2014 Nov 12.

7.

The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants.

Buss MC, Remke M, Lee J, Gandhi K, Schniederjan MJ, Kool M, Northcott PA, Pfister SM, Taylor MD, Castellino RC.

Oncogene. 2015 Feb 26;34(9):1126-40. doi: 10.1038/onc.2014.37. Epub 2014 Mar 17.

8.

The rationale for targeted therapies in medulloblastoma.

MacDonald TJ, Aguilera D, Castellino RC.

Neuro Oncol. 2014 Jan;16(1):9-20. doi: 10.1093/neuonc/not147. Epub 2013 Dec 4. Review.

9.

Response of subependymal giant cell astrocytoma with spinal cord metastasis to everolimus.

Aguilera D, Flamini R, Mazewski C, Schniederjan M, Hayes L, Boydston W, Castellino RC, MacDonald TJ.

J Pediatr Hematol Oncol. 2014 Oct;36(7):e448-51. doi: 10.1097/MPH.0000000000000005.

10.

MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.

Gayle SS, Castellino RC, Buss MC, Nahta R.

Curr Med Chem. 2013;20(19):2486-99.

11.

Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience.

Aguilera D, Mazewski C, Fangusaro J, MacDonald TJ, McNall-Knapp RY, Hayes LL, Kim S, Castellino RC.

Childs Nerv Syst. 2013 Apr;29(4):589-96. doi: 10.1007/s00381-012-2013-4. Epub 2013 Jan 8.

12.

HDM2 promotes WIP1-mediated medulloblastoma growth.

Buss MC, Read TA, Schniederjan MJ, Gandhi K, Castellino RC.

Neuro Oncol. 2012 Apr;14(4):440-58. doi: 10.1093/neuonc/nos001. Epub 2012 Feb 29.

13.

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.

Abouantoun TJ, Castellino RC, MacDonald TJ.

J Neurooncol. 2011 Jan;101(2):215-26. doi: 10.1007/s11060-010-0259-9. Epub 2010 Jun 4.

14.

Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.

Castellino RC, Barwick BG, Schniederjan M, Buss MC, Becher O, Hambardzumyan D, Macdonald TJ, Brat DJ, Durden DL.

PLoS One. 2010 May 26;5(5):e10849. doi: 10.1371/journal.pone.0010849.

15.

PI-3 kinase-PTEN signaling node: an intercept point for the control of angiogenesis.

Castellino RC, Muh CR, Durden DL.

Curr Pharm Des. 2009;15(4):380-8. Review.

PMID:
19199965
16.

Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors.

Castellino RC, Durden DL.

Nat Clin Pract Neurol. 2007 Dec;3(12):682-93. Review.

PMID:
18046441
17.

Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D.

Castellino RC, De Bortoli M, Lu X, Moon SH, Nguyen TA, Shepard MA, Rao PH, Donehower LA, Kim JY.

J Neurooncol. 2008 Feb;86(3):245-56. Epub 2007 Oct 12.

18.

Overexpressed TP73 induces apoptosis in medulloblastoma.

Castellino RC, De Bortoli M, Lin LL, Skapura DG, Rajan JA, Adesina AM, Perlaky L, Irwin MS, Kim JY.

BMC Cancer. 2007 Jul 12;7:127.

19.

Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases.

De Bortoli M, Castellino RC, Skapura DG, Shen JJ, Su JM, Russell HV, Hicks MJ, Man TK, Kim JY.

Eur J Cancer. 2007 May;43(8):1308-17. Epub 2007 Apr 30.

PMID:
17467979
20.

Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8.

De Bortoli M, Castellino RC, Lu XY, Deyo J, Sturla LM, Adesina AM, Perlaky L, Pomeroy SL, Lau CC, Man TK, Rao PH, Kim JY.

BMC Cancer. 2006 Sep 12;6:223.

Supplemental Content

Loading ...
Support Center