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Items: 1 to 20 of 42


Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts.

Benchetrit H, Jaber M, Zayat V, Sebban S, Pushett A, Makedonski K, Zakheim Z, Radwan A, Maoz N, Lasry R, Renous N, Inbar M, Ram O, Kaplan T, Buganim Y.

Cell Stem Cell. 2019 Jun 6;24(6):983-994.e7. doi: 10.1016/j.stem.2019.03.018. Epub 2019 Apr 25.


Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming.

Ward C, Volpe G, Cauchy P, Ptasinska A, Almaghrabi R, Blakemore D, Nafria M, Kestner D, Frampton J, Murphy G, Buganim Y, Kaji K, GarcĂ­a P.

Cell Rep. 2018 Aug 7;24(6):1496-1511.e8. doi: 10.1016/j.celrep.2018.07.026.


Germline DNA replication timing shapes mammalian genome composition.

Yehuda Y, Blumenfeld B, Mayorek N, Makedonski K, Vardi O, Cohen-Daniel L, Mansour Y, Baror-Sebban S, Masika H, Farago M, Berger M, Carmi S, Buganim Y, Koren A, Simon I.

Nucleic Acids Res. 2018 Sep 19;46(16):8299-8310. doi: 10.1093/nar/gky610.


Programming asynchronous replication in stem cells.

Masika H, Farago M, Hecht M, Condiotti R, Makedonski K, Buganim Y, Burstyn-Cohen T, Bergman Y, Cedar H.

Nat Struct Mol Biol. 2017 Dec;24(12):1132-1138. doi: 10.1038/nsmb.3503. Epub 2017 Nov 13.


Acquisition of the pluripotent and trophectoderm states in the embryo and during somatic nuclear reprogramming.

Jaber M, Sebban S, Buganim Y.

Curr Opin Genet Dev. 2017 Oct;46:37-43. doi: 10.1016/j.gde.2017.06.012. Epub 2017 Jun 30. Review.


Moving towards totipotency without a single miR-acle.

Maoz N, Buganim Y.

Cell Res. 2017 May;27(5):600-601. doi: 10.1038/cr.2017.30. Epub 2017 Mar 10.


Back to basics: Refined nuclear reprogramming techniques yield higher-quality stem cells.

Buganim Y.

Science. 2016 Jun 17;352(6292):1401. doi: 10.1126/science.aag1215. No abstract available.


Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos.

Cohen MA, Wert KJ, Goldmann J, Markoulaki S, Buganim Y, Fu D, Jaenisch R.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1570-5. doi: 10.1073/pnas.1525518113. Epub 2016 Jan 25.


Nuclear Reprogramming by Defined Factors: Quantity Versus Quality.

Sebban S, Buganim Y.

Trends Cell Biol. 2016 Jan;26(1):65-75. doi: 10.1016/j.tcb.2015.08.006. Epub 2015 Oct 1. Review.


Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells.

Benchetrit H, Herman S, van Wietmarschen N, Wu T, Makedonski K, Maoz N, Yom Tov N, Stave D, Lasry R, Zayat V, Xiao A, Lansdorp PM, Sebban S, Buganim Y.

Cell Stem Cell. 2015 Nov 5;17(5):543-56. doi: 10.1016/j.stem.2015.08.006. Epub 2015 Sep 24.


Tex10: A New Player in the Core Pluripotency Circuitry.

Buganim Y.

Cell Stem Cell. 2015 Jun 4;16(6):572-3. doi: 10.1016/j.stem.2015.04.019.


The developmental potential of iPSCs is greatly influenced by reprogramming factor selection.

Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, Kulenkampff E, Faddah DA, Shi L, Gao Q, Sarkar S, Cohen M, Goldmann J, Nery JR, Schultz MD, Ecker JR, Xiao A, Young RA, Lansdorp PM, Jaenisch R.

Cell Stem Cell. 2014 Sep 4;15(3):295-309. doi: 10.1016/j.stem.2014.07.003.


Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease.

Sarkar S, Carroll B, Buganim Y, Maetzel D, Ng AH, Cassady JP, Cohen MA, Chakraborty S, Wang H, Spooner E, Ploegh H, Gsponer J, Korolchuk VI, Jaenisch R.

Cell Rep. 2013 Dec 12;5(5):1302-15. doi: 10.1016/j.celrep.2013.10.042. Epub 2013 Nov 27.


Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs.

Faddah DA, Wang H, Cheng AW, Katz Y, Buganim Y, Jaenisch R.

Cell Stem Cell. 2013 Jul 3;13(1):23-9. doi: 10.1016/j.stem.2013.04.019.


Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling.

Sahay G, Querbes W, Alabi C, Eltoukhy A, Sarkar S, Zurenko C, Karagiannis E, Love K, Chen D, Zoncu R, Buganim Y, Schroeder A, Langer R, Anderson DG.

Nat Biotechnol. 2013 Jul;31(7):653-8. doi: 10.1038/nbt.2614. Epub 2013 Jun 23.


Mechanisms and models of somatic cell reprogramming.

Buganim Y, Faddah DA, Jaenisch R.

Nat Rev Genet. 2013 Jun;14(6):427-39. doi: 10.1038/nrg3473. Review.


p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity.

Molchadsky A, Ezra O, Amendola PG, Krantz D, Kogan-Sakin I, Buganim Y, Rivlin N, Goldfinger N, Folgiero V, Falcioni R, Sarig R, Rotter V.

Cell Death Differ. 2013 May;20(5):774-83. doi: 10.1038/cdd.2013.9. Epub 2013 Feb 15.


Transdifferentiation by defined factors as a powerful research tool to address basic biological questions.

Buganim Y, Jaenisch R.

Cell Cycle. 2012 Dec 15;11(24):4485-6. doi: 10.4161/cc.22665. Epub 2012 Nov 19. No abstract available.


Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.

Buganim Y, Faddah DA, Cheng AW, Itskovich E, Markoulaki S, Ganz K, Klemm SL, van Oudenaarden A, Jaenisch R.

Cell. 2012 Sep 14;150(6):1209-22. doi: 10.1016/j.cell.2012.08.023.


Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors.

Buganim Y, Itskovich E, Hu YC, Cheng AW, Ganz K, Sarkar S, Fu D, Welstead GG, Page DC, Jaenisch R.

Cell Stem Cell. 2012 Sep 7;11(3):373-86. doi: 10.1016/j.stem.2012.07.019.

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