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See 1 citation in 1995 by Abae and Brackett and Lynne and Padron:

J Assist Reprod Genet. 1995 Mar;12(3):210-6.

Treatment by assisted conception of severe male factor infertility due to spinal cord injury or other neurologic impairment.

Author information

1
Miami Project to Cure Paralysis, University of Miami School of Medicine, Florida 33136, USA.

Abstract

PURPOSE:

This retrospective study evaluated the pregnancy rates of 23 couples with male factor infertility due to traumatic spinal cord injury (N = 21), multiple sclerosis (N = 1) or transverse myelitis (N = 1).

METHODS:

Ovulation induction by clomiphene citrate or gonadotropins was used in combination with intrauterine insemination as an initial approach for assisted conception in all but one couple.

RESULTS:

Six pregnancies occurred in 60 cycles of intrauterine insemination (mean of 2.6 cycles). In this group, the cumulative pregnancy rate was 26%. Six couples who failed after a total of 33 intrauterine insemination cycles (mean of 5.5 cycles), and 1 couple with no previous intrauterine insemination cycles, initiated 10 cycles of in vitro fertilization (mean of 1.4 cycles). In this group, five pregnancies occurred. The pregnancy rate was 71%.

CONCLUSION:

We conclude that ovulation induction in combination with intrauterine insemination offers an effective initial therapy of severe male factor infertility due to spinal cord injury.

PMID:
8520188
[Indexed for MEDLINE]

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