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Page 1
Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2.
J Pharmacol Exp Ther. 2008 Oct;327(1):1-9. doi: 10.1124/jpet.108.140723. Epub 2008 Jul 3.
J Pharmacol Exp Ther. 2008.
PMID: 18599682
Functional study on TRPV1-mediated signalling in the mouse small intestine: involvement of tachykinin receptors.
de Man JG, Boeckx S, Anguille S, de Winter BY, de Schepper HU, Herman AG, Pelckmans PA.
de Man JG, et al. Among authors: boeckx s.
Neurogastroenterol Motil. 2008 May;20(5):546-56. doi: 10.1111/j.1365-2982.2007.01064.x. Epub 2008 Jan 13.
Neurogastroenterol Motil. 2008.
PMID: 18194153
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2-Mercaptoimidazoles, a new class of potent CCR2 antagonists.
Van Lomen G, Doyon J, Coesemans E, Boeckx S, Cools M, Buntinx M, Hermans B, Van Wauwe J.
Van Lomen G, et al. Among authors: boeckx s.
Bioorg Med Chem Lett. 2005 Feb 1;15(3):497-500. doi: 10.1016/j.bmcl.2004.11.064.
Bioorg Med Chem Lett. 2005.
PMID: 15729771
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Discovery of potent, orally bioavailable small-molecule inhibitors of the human CCR2 receptor.
Doyon J, Coesemans E, Boeckx S, Buntinx M, Hermans B, Van Wauwe JP, Gilissen RA, De Groot AH, Corens D, Van Lommen G.
Doyon J, et al. Among authors: boeckx s.
ChemMedChem. 2008 Apr;3(4):660-9. doi: 10.1002/cmdc.200700276.
ChemMedChem. 2008.
PMID: 18188859
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Postsurgical compartment syndrome of the forearm diagnosed in a child receiving a continuous infra-clavicular peripheral nerve block.
Sermeus L, Boeckx S, Camerlynck H, Somville J, Vercauteren M.
Sermeus L, et al. Among authors: boeckx s.
Acta Anaesthesiol Belg. 2015;66(1):29-32.
Acta Anaesthesiol Belg. 2015.
PMID: 26103739
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