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Items: 1 to 20 of 32

1.

Abacavir Induces Arterial Thrombosis in a Murine Model.

Collado-Diaz V, Andujar I, Sanchez-Lopez A, Orden S, Blanch-Ruiz MA, Martinez-Cuesta MA, Blas-García A, Esplugues JV, Álvarez Á.

J Infect Dis. 2018 Jun 20;218(2):228-233. doi: 10.1093/infdis/jiy001.

PMID:
29346575
2.

Ensuring the Consistency of Biosimilars.

Perez IA, Blas-Garcia A, Carmona L, Esplugues JV.

Curr Pharm Des. 2017;23(44):6733-6738. doi: 10.2174/1381612824666171204101657.

PMID:
29205112
3.

Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug-induced toxicity in vitro.

Alegre F, Moragrega ÁB, Polo M, Marti-Rodrigo A, Esplugues JV, Blas-Garcia A, Apostolova N.

Br J Pharmacol. 2018 Feb;175(3):440-455. doi: 10.1111/bph.14093. Epub 2018 Jan 6.

PMID:
29148034
4.

Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress.

Polo M, Alegre F, Moragrega AB, Gibellini L, Marti-Rodrigo A, Blas-Garcia A, Esplugues JV, Apostolova N.

Br J Pharmacol. 2017 Dec;174(23):4409-4429. doi: 10.1111/bph.14045. Epub 2017 Nov 7.

5.

Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects.

Apostolova N, Blas-Garcia A, Galindo MJ, Esplugues JV.

Eur J Pharmacol. 2017 Oct 5;812:163-173. doi: 10.1016/j.ejphar.2017.07.016. Epub 2017 Jul 8. Review.

PMID:
28690189
6.

Tenofovir-induced toxicity in renal proximal tubular epithelial cells: involvement of mitochondria.

Milián L, Peris JE, Gandía P, Andújar I, Pallardó L, Górriz JL, Blas-García A.

AIDS. 2017 Jul 31;31(12):1679-1684. doi: 10.1097/QAD.0000000000001572.

PMID:
28650379
7.

Oxidative and endoplasmic reticulum stress is impaired in leukocytes from metabolically unhealthy vs healthy obese individuals.

Bañuls C, Rovira-Llopis S, Lopez-Domenech S, Diaz-Morales N, Blas-Garcia A, Veses S, Morillas C, Victor VM, Rocha M, Hernandez-Mijares A.

Int J Obes (Lond). 2017 Oct;41(10):1556-1563. doi: 10.1038/ijo.2017.147. Epub 2017 Jun 20.

PMID:
28630460
8.

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

Hicks DF, Goossens N, Blas-García A, Tsuchida T, Wooden B, Wallace MC, Nieto N, Lade A, Redhead B, Cederbaum AI, Dudley JT, Fuchs BC, Lee YA, Hoshida Y, Friedman SL.

Sci Rep. 2017 Mar 3;7:42563. doi: 10.1038/srep42563.

9.

Endoplasmic Reticulum and Mitochondria: Independent Roles and Crosstalk in Fatty Liver Diseases and Hepatic Inflammation.

Blas-García A, Apostolova N, Valls-Bellés V, Esplugues JV.

Curr Pharm Des. 2016;22(18):2607-18. Review.

PMID:
26845326
10.

The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction.

Blas-García A, Martí-Rodrigo A, Víctor VM, Polo M, Alegre F, Funes HA, Apostolova N, Esplugues JV.

J Antimicrob Chemother. 2016 Apr;71(4):916-26. doi: 10.1093/jac/dkv424. Epub 2016 Jan 7.

PMID:
26747094
11.

Differential effects of anti-TNF-α and anti-IL-12/23 agents on human leukocyte-endothelial cell interactions.

Ríos-Navarro C, de Pablo C, Collado-Diaz V, Orden S, Blas-Garcia A, Martínez-Cuesta MÁ, Esplugues JV, Alvarez A.

Eur J Pharmacol. 2015 Oct 15;765:355-65. doi: 10.1016/j.ejphar.2015.08.054. Epub 2015 Sep 4.

12.

Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?

Rovira-Llopis S, Díaz-Morales N, Bañuls C, Blas-García A, Polo M, López-Domenech S, Jover A, Rocha M, Hernández-Mijares A, Víctor VM.

Antioxid Redox Signal. 2015 Nov 1;23(13):1050-6. doi: 10.1089/ars.2015.6447. Epub 2015 Aug 19.

PMID:
26218267
13.

Efavirenz and the CNS: what we already know and questions that need to be answered.

Apostolova N, Funes HA, Blas-Garcia A, Galindo MJ, Alvarez A, Esplugues JV.

J Antimicrob Chemother. 2015 Oct;70(10):2693-708. doi: 10.1093/jac/dkv183. Epub 2015 Jul 22. Review.

PMID:
26203180
14.

Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines.

Funes HA, Blas-Garcia A, Esplugues JV, Apostolova N.

J Antimicrob Chemother. 2015 Aug;70(8):2249-54. doi: 10.1093/jac/dkv098. Epub 2015 Apr 29.

PMID:
25925594
15.

Involvement of nitric oxide in the mitochondrial action of efavirenz: a differential effect on neurons and glial cells.

Apostolova N, Funes HA, Blas-Garcia A, Alegre F, Polo M, Esplugues JV.

J Infect Dis. 2015 Jun 15;211(12):1953-8. doi: 10.1093/infdis/jiu825. Epub 2014 Dec 23.

PMID:
25538272
16.

Mitochondrial (dys)function - a factor underlying the variability of efavirenz-induced hepatotoxicity?

Polo M, Alegre F, Funes HA, Blas-Garcia A, Victor VM, Esplugues JV, Apostolova N.

Br J Pharmacol. 2015 Apr;172(7):1713-27. doi: 10.1111/bph.13018. Epub 2015 Jan 8.

17.

Lack of mitochondrial toxicity of darunavir, raltegravir and rilpivirine in neurons and hepatocytes: a comparison with efavirenz.

Blas-García A, Polo M, Alegre F, Funes HA, Martínez E, Apostolova N, Esplugues JV.

J Antimicrob Chemother. 2014 Nov;69(11):2995-3000. doi: 10.1093/jac/dku262. Epub 2014 Jul 9.

PMID:
25011651
18.

Neuronal bioenergetics and acute mitochondrial dysfunction: a clue to understanding the central nervous system side effects of efavirenz.

Funes HA, Apostolova N, Alegre F, Blas-Garcia A, Alvarez A, Marti-Cabrera M, Esplugues JV.

J Infect Dis. 2014 Nov 1;210(9):1385-95. doi: 10.1093/infdis/jiu273. Epub 2014 May 9.

PMID:
24813473
19.

The pivotal role of nitric oxide: effects on the nervous and immune systems.

Banuls C, Rocha M, Rovira-Llopis S, Falcon R, Castello R, Herance JR, Polo M, Blas-Garcia A, Hernandez-Mijares A, Victor VM.

Curr Pharm Des. 2014;20(29):4679-89. Review.

PMID:
24588818
20.

ER stress in human hepatic cells treated with Efavirenz: mitochondria again.

Apostolova N, Gomez-Sucerquia LJ, Alegre F, Funes HA, Victor VM, Barrachina MD, Blas-Garcia A, Esplugues JV.

J Hepatol. 2013 Oct;59(4):780-9. doi: 10.1016/j.jhep.2013.06.005. Epub 2013 Jun 17.

PMID:
23792026

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