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Protoberberine compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cancer therapy.

Warowicka A, Łukasz P, Grażyna B, Oskar M, Jagoda LC, Dorota K, Robert N, Stefan J, Anna GJ.

Phytomedicine. 2019 Apr 9;64:152919. doi: 10.1016/j.phymed.2019.152919. [Epub ahead of print]


Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells.

Shinji S, Nakamura S, Nihashi Y, Umezawa K, Takaya T.

Biosci Biotechnol Biochem. 2019 Aug 29:1-13. doi: 10.1080/09168451.2019.1659714. [Epub ahead of print]


An Insight Into the Molecular Mechanism of Berberine Towards Multiple Cancer Types Through Systems Pharmacology.

Guo P, Cai C, Wu X, Fan X, Huang W, Zhou J, Wu Q, Huang Y, Zhao W, Zhang F, Wang Q, Zhang Y, Fang J.

Front Pharmacol. 2019 Aug 6;10:857. doi: 10.3389/fphar.2019.00857. eCollection 2019.


Cytotoxic and Proapoptotic Activity of Sanguinarine, Berberine, and Extracts of Chelidonium majus L. and Berberis thunbergii DC. toward Hematopoietic Cancer Cell Lines.

Och A, Zalewski D, Komsta Ł, Kołodziej P, Kocki J, Bogucka-Kocka A.

Toxins (Basel). 2019 Aug 23;11(9). pii: E485. doi: 10.3390/toxins11090485.


Dodecyl-TPP Targets Mitochondria and Potently Eradicates Cancer Stem Cells (CSCs): Synergy With FDA-Approved Drugs and Natural Compounds (Vitamin C and Berberine).

De Francesco EM, Ózsvári B, Sotgia F, Lisanti MP.

Front Oncol. 2019 Aug 7;9:615. doi: 10.3389/fonc.2019.00615. eCollection 2019.


Nano-Co-Delivery of Berberine and Anticancer Drug Using PLGA Nanoparticles: Exploration of Better Anticancer Activity and In Vivo Kinetics.

Khan I, Joshi G, Nakhate KT, Ajazuddin, Kumar R, Gupta U.

Pharm Res. 2019 Aug 16;36(10):149. doi: 10.1007/s11095-019-2677-5.


Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition.

Avila-Carrasco L, Majano P, Sánchez-Toméro JA, Selgas R, López-Cabrera M, Aguilera A, González Mateo G.

Front Pharmacol. 2019 Jul 30;10:715. doi: 10.3389/fphar.2019.00715. eCollection 2019. Review.


Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell.

Yao M, Fan X, Yuan B, Takagi N, Liu S, Han X, Ren J, Liu J.

BMC Complement Altern Med. 2019 Aug 14;19(1):216. doi: 10.1186/s12906-019-2615-4.


A novel hiPSC-derived system for hematoendothelial and myeloid blood toxicity screens identifies compounds promoting and inhibiting endothelial-to-hematopoietic transition.

Elcheva I, Sneed M, Frazee S, Liu Z, Zhu J, Wood T, Hendrickson S, Oehler C, Garcia B, Spiegelman VS.

Toxicol In Vitro. 2019 Aug 9;61:104622. doi: 10.1016/j.tiv.2019.104622. [Epub ahead of print]


Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies.

Liu DQ, Chen SP, Sun J, Wang XM, Chen N, Zhou YQ, Tian YK, Ye DW.

Pharmacol Res. 2019 Aug 7;148:104385. doi: 10.1016/j.phrs.2019.104385. [Epub ahead of print] Review.


Berberine inhibits epithelial-mesenchymal transition and promotes apoptosis of tumour-associated fibroblast-induced colonic epithelial cells through regulation of TGF-β signalling.

Huang C, Wang XL, Qi FF, Pang ZL.

J Cell Commun Signal. 2019 Aug 9. doi: 10.1007/s12079-019-00525-7. [Epub ahead of print]


Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.

Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W.

J Cell Mol Med. 2019 Jul 23. doi: 10.1111/jcmm.14560. [Epub ahead of print]


Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells.

Liu L, Fan J, Ai G, Liu J, Luo N, Li C, Cheng Z.

Biol Res. 2019 Jul 18;52(1):37. doi: 10.1186/s40659-019-0243-6.


13-Ethylberberine Induces Apoptosis through the Mitochondria-Related Apoptotic Pathway in Radiotherapy-Resistant Breast Cancer Cells.

Jin H, Ko YS, Park SW, Chang KC, Kim HJ.

Molecules. 2019 Jul 4;24(13). pii: E2448. doi: 10.3390/molecules24132448.


Quantification of Berberine in Berberis vulgaris L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity.

Ahmad S, Hussain A, Hussain A, Abdullah I, Ali MS, Froeyen M, Mirza MU.

Antioxidants (Basel). 2019 Jun 19;8(6). pii: E185. doi: 10.3390/antiox8060185.


Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition.

Li XD, Wang Z, Wang XR, Shao D, Zhang X, Li L, Ge MF, Chang ZM, Dong WF.

Int J Nanomedicine. 2019 May 29;14:3967-3982. doi: 10.2147/IJN.S206044. eCollection 2019.


Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis.

Xu J, Long Y, Ni L, Yuan X, Yu N, Wu R, Tao J, Zhang Y.

BMC Cancer. 2019 Jun 17;19(1):589. doi: 10.1186/s12885-019-5791-1.


hERG1 is involved in the pathophysiological process and inhibited by berberine in SKOV3 cells.

Zhi D, Zhou K, Yu D, Fan X, Zhang J, Li X, Dong M.

Oncol Lett. 2019 Jun;17(6):5653-5661. doi: 10.3892/ol.2019.10263. Epub 2019 Apr 17.


Long non‑coding RNA CASC2 enhances berberine‑induced cytotoxicity in colorectal cancer cells by silencing BCL2.

Dai W, Mu L, Cui Y, Li Y, Chen P, Xie H, Wang X.

Mol Med Rep. 2019 Aug;20(2):995-1006. doi: 10.3892/mmr.2019.10326. Epub 2019 Jun 3.

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