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Items: 1 to 20 of 33


Multiple lines of inhibitory feedback on AKT kinase in Schwann cells lacking TSC1/2 hint at distinct functions of mTORC1 and AKT in nerve development.

Wong KM, Beirowski B.

Commun Integr Biol. 2018 Feb 12;11(1):e1433441. doi: 10.1080/19420889.2018.1433441. eCollection 2018.


mTORC1 promotes Schwann cell cycling and myelinogenesis.

Beirowski B, Wong KM.

Cell Cycle. 2017 Sep 17;16(18):1637-1638. doi: 10.1080/15384101.2017.1360635. Epub 2017 Aug 18. No abstract available.


Axon degeneration: make the Schwann cell great again.

Wong KM, Babetto E, Beirowski B.

Neural Regen Res. 2017 Apr;12(4):518-524. doi: 10.4103/1673-5374.205000. Review.


mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells.

Beirowski B, Wong KM, Babetto E, Milbrandt J.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4261-E4270. doi: 10.1073/pnas.1620761114. Epub 2017 May 8.


Axon degeneration: Linking axonal bioenergetics to myelin.

Beirowski B, Babetto E, Wrabetz L.

J Cell Biol. 2016 Nov 21;215(4):437-440.


Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.

Beirowski B, Babetto E, Golden JP, Chen YJ, Yang K, Gross RW, Patti GJ, Milbrandt J.

Nat Neurosci. 2014 Oct;17(10):1351-61. doi: 10.1038/nn.3809. Epub 2014 Sep 7.


Concepts for regulation of axon integrity by enwrapping glia.

Beirowski B.

Front Cell Neurosci. 2013 Dec 19;7:256. doi: 10.3389/fncel.2013.00256. Review.


The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction.

Babetto E, Beirowski B, Russler EV, Milbrandt J, DiAntonio A.

Cell Rep. 2013 May 30;3(5):1422-9. doi: 10.1016/j.celrep.2013.04.013. Epub 2013 May 9.


Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.

Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V, DiAntonio A.

Neuron. 2012 Jun 21;74(6):1015-22. doi: 10.1016/j.neuron.2012.04.028.


Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.

Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26.


Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo.

Babetto E, Beirowski B, Janeckova L, Brown R, Gilley J, Thomson D, Ribchester RR, Coleman MP.

J Neurosci. 2010 Oct 6;30(40):13291-304. doi: 10.1523/JNEUROSCI.1189-10.2010.


Mechanisms of axonal spheroid formation in central nervous system Wallerian degeneration.

Beirowski B, Nógrádi A, Babetto E, Garcia-Alias G, Coleman MP.

J Neuropathol Exp Neurol. 2010 May;69(5):455-72. doi: 10.1097/NEN.0b013e3181da84db.


Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease.

Gross O, Girgert R, Beirowski B, Kretzler M, Kang HG, Kruegel J, Miosge N, Busse AC, Segerer S, Vogel WF, Müller GA, Weber M.

Matrix Biol. 2010 Jun;29(5):346-56. doi: 10.1016/j.matbio.2010.03.002. Epub 2010 Mar 20.


WldS can delay Wallerian degeneration in mice when interaction with valosin-containing protein is weakened.

Beirowski B, Morreale G, Conforti L, Mazzola F, Di Stefano M, Wilbrey A, Babetto E, Janeckova L, Magni G, Coleman MP.

Neuroscience. 2010 Mar 10;166(1):201-11. doi: 10.1016/j.neuroscience.2009.12.024. Epub 2009 Dec 16.


Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice.

Conforti L, Wilbrey A, Morreale G, Janeckova L, Beirowski B, Adalbert R, Mazzola F, Di Stefano M, Hartley R, Babetto E, Smith T, Gilley J, Billington RA, Genazzani AA, Ribchester RR, Magni G, Coleman M.

J Cell Biol. 2009 Feb 23;184(4):491-500. doi: 10.1083/jcb.200807175.


Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

Beirowski B, Babetto E, Gilley J, Mazzola F, Conforti L, Janeckova L, Magni G, Ribchester RR, Coleman MP.

J Neurosci. 2009 Jan 21;29(3):653-68. doi: 10.1523/JNEUROSCI.3814-08.2009.


The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model.

Beirowski B, Babetto E, Coleman MP, Martin KR.

Eur J Neurosci. 2008 Sep;28(6):1166-79. doi: 10.1111/j.1460-9568.2008.06426.x. Epub 2008 Sep 9.


VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).

Wilbrey AL, Haley JE, Wishart TM, Conforti L, Morreale G, Beirowski B, Babetto E, Adalbert R, Gillingwater TH, Smith T, Wyllie DJ, Ribchester RR, Coleman MP.

Mol Cell Neurosci. 2008 Jul;38(3):325-40. doi: 10.1016/j.mcn.2008.03.004. Epub 2008 Mar 25.


Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome.

Koepke ML, Weber M, Schulze-Lohoff E, Beirowski B, Segerer S, Gross O.

Nephrol Dial Transplant. 2007 Apr;22(4):1062-9. Epub 2007 Feb 6.


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