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Items: 1 to 20 of 202

1.

The CNS Immune Landscape from the Viewpoint of a T Cell.

Mundt S, Greter M, Flügel A, Becher B.

Trends Neurosci. 2019 Aug 29. pii: S0166-2236(19)30131-6. doi: 10.1016/j.tins.2019.07.008. [Epub ahead of print] Review.

PMID:
31474310
2.

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis.

Galli E, Hartmann FJ, Schreiner B, Ingelfinger F, Arvaniti E, Diebold M, Mrdjen D, van der Meer F, Krieg C, Nimer FA, Sanderson N, Stadelmann C, Khademi M, Piehl F, Claassen M, Derfuss T, Olsson T, Becher B.

Nat Med. 2019 Aug;25(8):1290-1300. doi: 10.1038/s41591-019-0521-4. Epub 2019 Jul 22.

PMID:
31332391
3.

Pathophysiological role of respiratory dysbiosis in hospital-acquired pneumonia.

Roquilly A, Torres A, Villadangos JA, Netea MG, Dickson R, Becher B, Asehnoune K.

Lancet Respir Med. 2019 Aug;7(8):710-720. doi: 10.1016/S2213-2600(19)30140-7. Epub 2019 Jun 7. Review.

PMID:
31182406
4.

Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry.

Brummelman J, Haftmann C, Núñez NG, Alvisi G, Mazza EMC, Becher B, Lugli E.

Nat Protoc. 2019 Jul;14(7):1946-1969. doi: 10.1038/s41596-019-0166-2. Epub 2019 Jun 3.

PMID:
31160786
5.

CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo.

Chatterjee B, Deng Y, Holler A, Nunez N, Azzi T, Vanoaica LD, Müller A, Zdimerova H, Antsiferova O, Zbinden A, Capaul R, Dreyer JH, Nadal D, Becher B, Robinson MD, Stauss H, Münz C.

PLoS Pathog. 2019 May 30;15(5):e1007748. doi: 10.1371/journal.ppat.1007748. eCollection 2019 May.

6.

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, Waisman A, Opitz L, Oukka M, Schreiner B, Pelczar P, Becher B.

Immunity. 2019 May 21;50(5):1289-1304.e6. doi: 10.1016/j.immuni.2019.04.006. Epub 2019 May 9.

PMID:
31079916
7.

Innate lymphoid cells as regulators of the tumor microenvironment.

Tugues S, Ducimetiere L, Friebel E, Becher B.

Semin Immunol. 2019 Feb;41:101270. doi: 10.1016/j.smim.2019.03.002. Epub 2019 Mar 11. Review.

PMID:
30871769
8.

Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells.

Hutmacher C, Gonzalo Núñez N, Liuzzi AR, Becher B, Neri D.

Cancer Immunol Res. 2019 Apr;7(4):572-583. doi: 10.1158/2326-6066.CIR-18-0566. Epub 2019 Feb 19.

PMID:
30782667
9.

Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation.

Mundt S, Mrdjen D, Utz SG, Greter M, Schreiner B, Becher B.

Sci Immunol. 2019 Jan 25;4(31). pii: eaau8380. doi: 10.1126/sciimmunol.aau8380.

PMID:
30679199
10.

ARTD1 in Myeloid Cells Controls the IL-12/18-IFN-γ Axis in a Model of Sterile Sepsis, Chronic Bacterial Infection, and Cancer.

Kunze FA, Bauer M, Komuczki J, Lanzinger M, Gunasekera K, Hopp AK, Lehmann M, Becher B, Müller A, Hottiger MO.

J Immunol. 2019 Mar 1;202(5):1406-1416. doi: 10.4049/jimmunol.1801107. Epub 2019 Jan 23.

PMID:
30674576
11.

Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.

Ciccarelli O, Cohen JA, Reingold SC, Weinshenker BG; International Conference on Spinal Cord Involvement and Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders.

Lancet Neurol. 2019 Feb;18(2):185-197. doi: 10.1016/S1474-4422(18)30460-5. Review.

PMID:
30663608
12.

The end of omics? High dimensional single cell analysis in precision medicine.

Galli E, Friebel E, Ingelfinger F, Unger S, Núñez NG, Becher B.

Eur J Immunol. 2019 Feb;49(2):212-220. doi: 10.1002/eji.201847758. Epub 2019 Jan 25. Review.

13.

Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation.

Hartwig T, Zwicky P, Schreiner B, Yawalkar N, Cheng P, Navarini A, Dummer R, Flatz L, Conrad C, Schlapbach C, Becher B.

Cell Rep. 2018 Dec 26;25(13):3564-3572.e4. doi: 10.1016/j.celrep.2018.12.012.

14.

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B.

Sci Transl Med. 2018 Nov 28;10(469). pii: eaat8410. doi: 10.1126/scitranslmed.aat8410.

PMID:
30487251
15.

Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosis.

Seyedsadr MS, Weinmann O, Amorim A, Ineichen BV, Egger M, Mirnajafi-Zadeh J, Becher B, Javan M, Schwab ME.

Neurobiol Dis. 2019 Apr;124:189-201. doi: 10.1016/j.nbd.2018.11.018. Epub 2018 Nov 22.

PMID:
30468865
16.

T cells in patients with narcolepsy target self-antigens of hypocretin neurons.

Latorre D, Kallweit U, Armentani E, Foglierini M, Mele F, Cassotta A, Jovic S, Jarrossay D, Mathis J, Zellini F, Becher B, Lanzavecchia A, Khatami R, Manconi M, Tafti M, Bassetti CL, Sallusto F.

Nature. 2018 Oct;562(7725):63-68. doi: 10.1038/s41586-018-0540-1. Epub 2018 Sep 19.

PMID:
30232458
17.

Author Correction: High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy.

Krieg C, Nowicka M, Guglietta S, Schindler S, Hartmann FJ, Weber LM, Dummer R, Robinson MD, Levesque MP, Becher B.

Nat Med. 2018 Nov;24(11):1773-1775. doi: 10.1038/s41591-018-0094-7.

PMID:
29967347
18.

Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes.

Nüesch U, Mauracher AA, Opitz L, Volkmer B, Michalak-Mićka K, Kamarashev J, Hartwig T, Reichmann E, Becher B, Vavassori S, Pachlopnik Schmid J.

J Allergy Clin Immunol. 2019 Jan;143(1):292-304.e8. doi: 10.1016/j.jaci.2018.02.057. Epub 2018 Jun 14.

PMID:
29775636
19.

CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis.

Beffinger M, Tallón de Lara P, Tugues S, Vermeer M, Montagnolo Y, Ohs I, Cecconi V, Lucchiari G, Gagliardi A, Misljencevic N, Sutton J, Spörri R, Becher B, Gupta A, van den Broek M.

JCI Insight. 2018 May 17;3(10). pii: 97792. doi: 10.1172/jci.insight.97792. eCollection 2018 May 17.

20.

Conditional Gene-Targeting in Mice: Problems and Solutions.

Becher B, Waisman A, Lu LF.

Immunity. 2018 May 15;48(5):835-836. doi: 10.1016/j.immuni.2018.05.002. No abstract available.

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