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Immunological differences between colorectal cancer and normal mucosa uncover a prognostically relevant immune cell profile.

Strasser K, Birnleitner H, Beer A, Pils D, Gerner MC, Schmetterer KG, Bachleitner-Hofmann T, Stift A, Bergmann M, Oehler R.

Oncoimmunology. 2018 Nov 5;8(2):e1537693. doi: 10.1080/2162402X.2018.1537693. eCollection 2019.


Plasma metabolites associated with colorectal cancer: A discovery-replication strategy.

Geijsen AJMR, Brezina S, Keski-Rahkonen P, Baierl A, Bachleitner-Hofmann T, Bergmann MM, Boehm J, Brenner H, Chang-Claude J, van Duijnhoven FJB, Gigic B, Gumpenberger T, Hofer P, Hoffmeister M, Holowatyj AN, Karner-Hanusch J, Kok DE, Leeb G, Ulvik A, Robinot N, Ose J, Stift A, Schrotz-King P, Ulrich AB, Ueland PM, Kampman E, Scalbert A, Habermann N, Gsur A, Ulrich CM.

Int J Cancer. 2019 Jan 21. doi: 10.1002/ijc.32146. [Epub ahead of print]


The ASAMET trial: a randomized, phase II, double-blind, placebo-controlled, multicenter, 2 × 2 factorial biomarker study of tertiary prevention with low-dose aspirin and metformin in stage I-III colorectal cancer patients.

Petrera M, Paleari L, Clavarezza M, Puntoni M, Caviglia S, Briata IM, Oppezzi M, Mislej EM, Stabuc B, Gnant M, Bachleitner-Hofmann T, Roth W, Scherer D, Haefeli WE, Ulrich CM, DeCensi A.

BMC Cancer. 2018 Dec 4;18(1):1210. doi: 10.1186/s12885-018-5126-7.


Predictive and Prognostic Implication of Bowel Resections During Primary Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer.

Bartl T, Schwameis R, Stift A, Bachleitner-Hofmann T, Reinthaller A, Grimm C, Polterauer S.

Int J Gynecol Cancer. 2018 Nov;28(9):1664-1671. doi: 10.1097/IGC.0000000000001369.


Circulating Free Methylated Tumor DNA Markers for Sensitive Assessment of Tumor Burden and Early Response Monitoring in Patients Receiving Systemic Chemotherapy for Colorectal Cancer Liver Metastasis.

Bhangu JS, Beer A, Mittlböck M, Tamandl D, Pulverer W, Schönthaler S, Taghizadeh H, Stremitzer S, Kaczirek K, Gruenberger T, Gnant M, Bergmann M, Mannhalter C, Weinhäusel A, Oehler R, Bachleitner-Hofmann T.

Ann Surg. 2018 Nov;268(5):894-902. doi: 10.1097/SLA.0000000000002901.


Leukocyte telomere length throughout the continuum of colorectal carcinogenesis.

Zöchmeister C, Brezina S, Hofer P, Baierl A, Bergmann MM, Bachleitner-Hofmann T, Karner-Hanusch J, Stift A, Gerger A, Leeb G, Mach K, Rachakonda S, Kumar R, Gsur A.

Oncotarget. 2018 Feb 7;9(17):13582-13592. doi: 10.18632/oncotarget.24431. eCollection 2018 Mar 2.


High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome.

Paleari L, Burhenne J, Weiss J, Foersch S, Roth W, Parodi A, Gnant M, Bachleitner-Hofmann T, Scherer D, Ulrich CM, Stabuc B, Puntoni M, Coccia G, Petrera M, Haefeli WE, DeCensi A.

Gastroenterology. 2018 Apr;154(5):1543-1545. doi: 10.1053/j.gastro.2017.12.040. Epub 2018 Mar 8. No abstract available.


Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

Hofer P, Hagmann M, Brezina S, Dolejsi E, Mach K, Leeb G, Baierl A, Buch S, Sutterlüty-Fall H, Karner-Hanusch J, Bergmann MM, Bachleitner-Hofmann T, Stift A, Gerger A, Rötzer K, Karner J, Stättner S, Waldenberger M, Meitinger T, Strauch K, Linseisen J, Gieger C, Frommlet F, Gsur A.

Oncotarget. 2017 Oct 9;8(58):98623-98634. doi: 10.18632/oncotarget.21697. eCollection 2017 Nov 17.


Circulating cell-free DNA in plasma of colorectal cancer patients - A potential biomarker for tumor burden.

Bhangu JS, Taghizadeh H, Braunschmid T, Bachleitner-Hofmann T, Mannhalter C.

Surg Oncol. 2017 Dec;26(4):395-401. doi: 10.1016/j.suronc.2017.08.001. Epub 2017 Aug 7.


Trocar-site evisceration of the vermiform appendix following laparoscopic sigmoid colectomy: A case report.

Bhangu JS, Exner R, Bachleitner-Hofmann T.

Int J Surg Case Rep. 2017;31:273-275. doi: 10.1016/j.ijscr.2017.01.066. Epub 2017 Feb 1.


Prognostic value of HMGB1 in early breast cancer patients under neoadjuvant chemotherapy.

Exner R, Sachet M, Arnold T, Zinn-Zinnenburg M, Michlmayr A, Dubsky P, Bartsch R, Steger G, Gnant M, Bergmann M, Bachleitner-Hofmann T, Oehler R.

Cancer Med. 2016 Sep;5(9):2350-8. doi: 10.1002/cam4.827. Epub 2016 Jul 25.


The type of loose seton for complex anal fistula is essential to improve perianal comfort and quality of life.

Kristo I, Stift A, Staud C, Kainz A, Bachleitner-Hofmann T, Chitsabesan P, Riss S.

Colorectal Dis. 2016 Jun;18(6):O194-8. doi: 10.1111/codi.13335.


Correlation of circular RNA abundance with proliferation--exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues.

Bachmayr-Heyda A, Reiner AT, Auer K, Sukhbaatar N, Aust S, Bachleitner-Hofmann T, Mesteri I, Grunt TW, Zeillinger R, Pils D.

Sci Rep. 2015 Jan 27;5:8057. doi: 10.1038/srep08057.


Genomic classifier ColoPrint predicts recurrence in stage II colorectal cancer patients more accurately than clinical factors.

Kopetz S, Tabernero J, Rosenberg R, Jiang ZQ, Moreno V, Bachleitner-Hofmann T, Lanza G, Stork-Sloots L, Maru D, Simon I, Capellà G, Salazar R.

Oncologist. 2015 Feb;20(2):127-33. doi: 10.1634/theoncologist.2014-0325. Epub 2015 Jan 5.


The Comfort Drain: a new device for treating complex anal fistula.

Riss S, Bachleitner-Hofmann T, Stift A.

Tech Coloproctol. 2014 Nov;18(11):1133-5. doi: 10.1007/s10151-014-1216-y. Epub 2014 Sep 26. No abstract available.


American Society of Peritoneal Surface Malignancies opinion statement on defining expectations from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with colorectal cancer.

Esquivel J, Piso P, Verwaal V, Bachleitner-Hofmann T, Glehen O, González-Moreno S, Deraco M, Pelz J, Alexander R, Glockzin G.

J Surg Oncol. 2014 Dec;110(7):777-8. doi: 10.1002/jso.23722. Epub 2014 Jul 8. No abstract available.


Peritoneal metastases from colorectal cancer: patient selection for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Riss S, Mohamed F, Dayal S, Cecil T, Stift A, Bachleitner-Hofmann T, Moran B.

Eur J Surg Oncol. 2013 Sep;39(9):931-7. doi: 10.1016/j.ejso.2013.06.001. Epub 2013 Jun 27. Review.


Plasma HMGB-1 after the initial dose of epirubicin/docetaxel in cancer.

Arnold T, Michlmayr A, Baumann S, Burghuber C, Pluschnig U, Bartsch R, Steger G, Gnant M, Bergmann M, Bachleitner-Hofmann T, Oehler R.

Eur J Clin Invest. 2013 Mar;43(3):286-91. doi: 10.1111/eci.12043. Epub 2013 Jan 25.


Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer.

Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, Bachleitner-Hofmann T, Bergmann M, Stift A, Gruenberger T, Brostjan C.

PLoS One. 2012;7(9):e44450. doi: 10.1371/journal.pone.0044450. Epub 2012 Sep 4.


Adjuvant sequencing of tamoxifen and anastrozole is superior to tamoxifen alone in postmenopausal women with low proliferating breast cancer.

Bago-Horvath Z, Rudas M, Dubsky P, Jakesz R, Singer CF, Kemmerling R, Greil R, Jelen A, Böhm G, Jasarevic Z, Haid A, Gruber C, Pöstlberger S, Filipits M, Gnant M; Austrian Breast and Colorectal Cancer Study Group.

Clin Cancer Res. 2011 Dec 15;17(24):7828-34. doi: 10.1158/1078-0432.CCR-11-1846. Epub 2011 Oct 13.

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