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Items: 1 to 20 of 717

1.

Pharmacophoric Site Identification and Inhibitor Design for Autotaxin.

Lee MH, Lee DY, Balupuri A, Jeong JW, Kang NS.

Molecules. 2019 Aug 1;24(15). pii: E2808. doi: 10.3390/molecules24152808.

2.

Treatment of Pruritus Secondary to Liver Disease.

Düll MM, Kremer AE.

Curr Gastroenterol Rep. 2019 Jul 31;21(9):48. doi: 10.1007/s11894-019-0713-6. Review.

PMID:
31367993
3.

Pleotropic Roles of Autotaxin in the Nervous System Present Opportunities for the Development of Novel Therapeutics for Neurological Diseases.

Herr DR, Chew WS, Satish RL, Ong WY.

Mol Neurobiol. 2019 Jul 30. doi: 10.1007/s12035-019-01719-1. [Epub ahead of print] Review.

PMID:
31364025
4.

Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia.

Fujii T, Nagamatsu T, Schust DJ, Ichikawa M, Kumasawa K, Yabe S, Iriyama T, Hirota Y, Osuga Y, Aoki J, Yatomi Y, Fujii T.

Am J Reprod Immunol. 2019 Jul 29:e13176. doi: 10.1111/aji.13176. [Epub ahead of print]

PMID:
31357233
5.

Lysophosphatidic Acid and Autotaxin-associated Effects on the Initiation and Progression of Colorectal Cancer.

Yun CC.

Cancers (Basel). 2019 Jul 9;11(7). pii: E958. doi: 10.3390/cancers11070958. Review.

6.

Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease.

Demer LL, Tintut Y.

Trends Endocrinol Metab. 2019 Jul 3. pii: S1043-2760(19)30118-3. doi: 10.1016/j.tem.2019.06.001. [Epub ahead of print] Review.

PMID:
31279666
7.

[18 F]PRIMATX, a New Positron Emission Tomography Tracer for Imaging of Autotaxin in Lung Tissue and Tumor-Bearing Mice.

Briard E, Joshi AD, Shanmukhappa S, Ilovich O, Auberson YP.

ChemMedChem. 2019 Jul 4. doi: 10.1002/cmdc.201900297. [Epub ahead of print]

PMID:
31273951
8.

Bioactive lipids regulate Trypanosoma cruzi development.

Chagas-Lima AC, Pereira MG, Fampa P, Lima MS, Kluck GEG, Atella GC.

Parasitol Res. 2019 Jul 2. doi: 10.1007/s00436-019-06331-9. [Epub ahead of print]

PMID:
31267245
9.

Enhancer-mediated enrichment of interacting JMJD3-DDX21 to ENPP2 locus prevents R-loop formation and promotes transcription.

Argaud D, Boulanger MC, Chignon A, Mkannez G, Mathieu P.

Nucleic Acids Res. 2019 Jun 28. pii: gkz560. doi: 10.1093/nar/gkz560. [Epub ahead of print]

PMID:
31251802
10.

Adipose tissue-derived autotaxin causes cardiomyopathy in obese mice.

Xu Y, Wang Y, Liu J, Cao W, Li L, Du H, Zhan E, Zhang R, Liu H, Xu M, Chen T, Qu Y, Yu B.

J Mol Endocrinol. 2019 Jun 1. pii: JME-18-0242.R2. doi: 10.1530/JME-18-0242. [Epub ahead of print]

PMID:
31247591
11.

LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling.

Mathew D, Kremer KN, Strauch P, Tigyi G, Pelanda R, Torres RM.

Front Immunol. 2019 May 28;10:1159. doi: 10.3389/fimmu.2019.01159. eCollection 2019.

12.

Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis.

Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR.

Sci Rep. 2019 Jun 11;9(1):8450. doi: 10.1038/s41598-019-44762-7.

13.

Rationale, design and objectives of two phase III, randomised, placebo-controlled studies of GLPG1690, a novel autotaxin inhibitor, in idiopathic pulmonary fibrosis (ISABELA 1 and 2).

Maher TM, Kreuter M, Lederer DJ, Brown KK, Wuyts W, Verbruggen N, Stutvoet S, Fieuw A, Ford P, Abi-Saab W, Wijsenbeek M.

BMJ Open Respir Res. 2019 May 21;6(1):e000422. doi: 10.1136/bmjresp-2019-000422. eCollection 2019.

14.

Osteoclast-derived Autotaxin, a distinguishing factor for inflammatory bone loss.

Flammier S, Peyruchaud O, Bourguillault F, Duboeuf F, Davignon JL, Norman DD, Isaac S, Marotte H, Tigyi G, Machuca-Gayet I, Coury F.

Arthritis Rheumatol. 2019 Jun 4. doi: 10.1002/art.41005. [Epub ahead of print]

PMID:
31162832
15.

Autotaxin is a valuable biomarker for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease.

Honda Y, Imajo K, Kobayashi T, Kessoku T, Ogawa Y, Tomeno W, Yoneda M, Kobayashi N, Saito S, Nakajima A.

Hepatol Res. 2019 May 29. doi: 10.1111/hepr.13382. [Epub ahead of print]

PMID:
31144415
16.

Autotaxin-Lysophosphatidic Acid Axis Blockade Improves Inflammation by Regulating Th17 Cell Differentiation in DSS-Induced Chronic Colitis Mice.

Dong YL, Duan XY, Liu YJ, Fan H, Xu M, Chen QY, Nan Z, Wu H, Deng SJ.

Inflammation. 2019 May 17. doi: 10.1007/s10753-019-01015-z. [Epub ahead of print]

PMID:
31102124
17.

The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage.

Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, Kitajima S, Sagara A, Miyake T, Toyama T, Sato K, Nakagawa S, Shimizu M, Kaneko S, Wada T.

Sci Rep. 2019 May 15;9(1):7414. doi: 10.1038/s41598-019-43576-x.

18.

Phospholipid levels in blood during community-acquired pneumonia.

Müller DC, Kauppi A, Edin A, Gylfe Å, Sjöstedt AB, Johansson A.

PLoS One. 2019 May 7;14(5):e0216379. doi: 10.1371/journal.pone.0216379. eCollection 2019.

19.

A FATal Combination: Fibroblast-Derived Lipids and Cancer-Derived Autotaxin Promote Pancreatic Cancer Growth.

Biffi G, Tuveson DA.

Cancer Discov. 2019 May;9(5):578-580. doi: 10.1158/2159-8290.CD-19-0273.

PMID:
31043410
20.

Expression of Autotaxin⁻Lysophosphatidate Signaling-Related Proteins in Breast Cancer with Adipose Stroma.

Cha YJ, Koo JS.

Int J Mol Sci. 2019 Apr 29;20(9). pii: E2102. doi: 10.3390/ijms20092102.

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