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Items: 1 to 20 of 651

1.

Therapeutic plasma exchange as a novel treatment for severe intrahepatic cholestasis of pregnancy: Case series and mechanism of action.

Ovadia C, Lövgren-Sandblom A, Edwards LA, Langedijk J, Geenes V, Chambers J, Cheng F, Clarke L, Begum S, Noori M, Pusey C, Padmagirison R, Agarwal S, Peerless J, Cheesman K, Heneghan M, Oude Elferink R, Patel VC, Marschall HU, Williamson C.

J Clin Apher. 2018 Oct 15. doi: 10.1002/jca.21654. [Epub ahead of print]

PMID:
30321466
2.

High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells.

Huang YL, Lin YC, Lin CC, Chen WM, Chen BPC, Lee H.

Cell Physiol Biochem. 2018 Oct 12;50(2):597-611. doi: 10.1159/000494177. [Epub ahead of print]

3.

The interaction of β2-glycoprotein I with lysophosphatidic acid in platelet aggregation and blood clotting.

Sato A, Nakazawa K, Sugawara A, Yamazaki Y, Ebina K.

Biochim Biophys Acta Proteins Proteom. 2018 Oct 9;1866(12):1232-1241. doi: 10.1016/j.bbapap.2018.10.004. [Epub ahead of print]

PMID:
30312773
4.

Production of extracellular lysophosphatidic acid in the regulation of adipocyte functions and liver fibrosis.

Yang F, Chen GX.

World J Gastroenterol. 2018 Sep 28;24(36):4132-4151. doi: 10.3748/wjg.v24.i36.4132. Review.

5.

Regulation of tumor cell - Microenvironment interaction by the autotaxin-lysophosphatidic acid receptor axis.

Tigyi GJ, Yue J, Norman DD, Szabo E, Balogh A, Balazs L, Zhao G, Lee SC.

Adv Biol Regul. 2018 Sep 16. pii: S2212-4926(18)30135-0. doi: 10.1016/j.jbior.2018.09.008. [Epub ahead of print] Review.

PMID:
30243984
6.

Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis.

Leblanc R, Sahay D, Houssin A, Machuca-Gayet I, Peyruchaud O.

Oncotarget. 2018 Sep 4;9(69):33170-33185. doi: 10.18632/oncotarget.26039. eCollection 2018 Sep 4.

7.

Antipruritic effect of bezafibrate and serum autotaxin measures in patients with primary biliary cholangitis.

Kremer AE, Le Cleac'h A, Lemoinne S, Wolf K, De Chaisemartin L, Chollet-Martin S, Humbert L, Rainteau D, Poupon R, Rousseau A, Chazouillères O, Corpechot C.

Gut. 2018 Sep 18. pii: gutjnl-2018-317426. doi: 10.1136/gutjnl-2018-317426. [Epub ahead of print] No abstract available.

PMID:
30228218
8.

Serum Autotaxin Concentrations Reflect Changes in Liver Stiffness and Fibrosis After Antiviral Therapy in Patients with Chronic Hepatitis C.

Ando W, Yokomori H, Kaneko F, Kaneko M, Igarashi K, Suzuki H.

Hepatol Commun. 2018 Aug 23;2(9):1111-1122. doi: 10.1002/hep4.1230. eCollection 2018 Sep.

9.

Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis.

Ninou I, Kaffe E, Müller S, Budd DC, Stevenson CS, Ullmer C, Aidinis V.

Pulm Pharmacol Ther. 2018 Oct;52:32-40. doi: 10.1016/j.pupt.2018.08.003. Epub 2018 Sep 7.

PMID:
30201409
10.

Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer.

Meng G, Tang X, Yang Z, Zhao Y, Curtis JM, McMullen TPW, Brindley DN.

FASEB J. 2018 Sep 7:fj201801226R. doi: 10.1096/fj.201801226R. [Epub ahead of print]

PMID:
30192654
11.

Design, Synthesis, And Preliminary Bioactivity Evaluation Of 2,7-Substituted Carbazole Derivatives As Potent Autotaxin Inhibitors And Antitumor Agents.

Wang W, Zhao F, Zhao Y, Pan W, Cao P, Wu L, Wang Z, Zhao X, Zhao Y, Wang H.

Anticancer Agents Med Chem. 2018 Aug 30. doi: 10.2174/1871520618666180830161821. [Epub ahead of print]

PMID:
30173652
12.

Inhibition of autotaxin alleviates inflammation and increases the expression of sodium-dependent glucose cotransporter 1 and Na+/H+ exchanger 3 in SAMP1/Fc mice.

He P, Haque A, Lin S, Cominelli F, Yun CC.

Am J Physiol Gastrointest Liver Physiol. 2018 Aug 17. doi: 10.1152/ajpgi.00215.2018. [Epub ahead of print]

PMID:
30118349
13.

Deficiency of alkaline SMase enhances dextran sulfate sodium-induced colitis in mice with upregulation of autotaxin.

Zhang P, Chen Y, Zhang T, Zhu J, Zhao L, Li J, Wang G, Li Y, Xu S, Nilsson Å, Duan RD.

J Lipid Res. 2018 Oct;59(10):1841-1850. doi: 10.1194/jlr.M084285. Epub 2018 Aug 7.

PMID:
30087205
14.

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism.

D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC.

J Lipid Res. 2018 Oct;59(10):1805-1817. doi: 10.1194/jlr.M082008. Epub 2018 Aug 2.

PMID:
30072447
15.

Hepatic autotaxin overexpression in infants with biliary atresia.

Udomsinprasert W, Vejchapipat P, Klaikeaw N, Chongsrisawat V, Poovorawan Y, Honsawek S.

PeerJ. 2018 Jul 24;6:e5224. doi: 10.7717/peerj.5224. eCollection 2018.

16.

The atherogenic actions of LPC on vascular smooth muscle cells and its LPA receptor mediated mechanism.

Bao L, Qi J, Wang YW, Xi Q, Tserennadmid T, Zhao PF, Qi J, Damirin A.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1911-1918. doi: 10.1016/j.bbrc.2018.07.135. Epub 2018 Jul 29.

PMID:
30064908
17.

Synthesis and Activity of a Novel Autotaxin Inhibitor-Icodextrin Conjugate.

Fisher N, Edwards MG, Hemming R, Allin SM, Wallis JD, Bulman Page PC, Mckenzie MJ, Jones SM, Elsegood MRJ, King-Underwood J, Richardson A.

J Med Chem. 2018 Sep 13;61(17):7942-7951. doi: 10.1021/acs.jmedchem.8b00935. Epub 2018 Aug 15.

PMID:
30059212
18.

Increased aqueous autotaxin and lysophosphatidic acid levels are potential prognostic factors after trabeculectomy in different types of glaucoma.

Igarashi N, Honjo M, Kurano M, Yatomi Y, Igarashi K, Kano K, Aoki J, Aihara M.

Sci Rep. 2018 Jul 27;8(1):11304. doi: 10.1038/s41598-018-29649-3.

19.

LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer.

Lin YC, Chen CC, Chen WM, Lu KY, Shen TL, Jou YC, Shen CH, Ohbayashi N, Kanaho Y, Huang YL, Lee H.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1305-1315. doi: 10.1016/j.bbalip.2018.07.005. Epub 2018 Jul 24.

PMID:
30053596
20.

Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals.

Sugiura A, Joshita S, Umemura T, Yamazaki T, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Usami Y, Wada S, Mori H, Shibata S, Yoshizawa K, Morita S, Furuta K, Kamijo A, Iijima A, Kako S, Maruyama A, Kobayashi M, Komatsu M, Matsumura M, Miyabayashi C, Ichijo T, Takeuchi A, Koike Y, Gibo Y, Tsukadaira T, Inada H, Kiyosawa K, Tanaka E.

J Viral Hepat. 2018 Jul 25. doi: 10.1111/jvh.12973. [Epub ahead of print]

PMID:
30044517

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