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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1978 1
1979 1
1980 2
1981 1
1982 2
1984 1
1990 1
1991 1
1992 2
1993 1
1994 2
1995 2
1996 1
1997 2
1998 4
1999 1
2000 3
2001 5
2002 8
2003 9
2004 16
2005 23
2006 40
2007 63
2008 108
2009 151
2010 186
2011 203
2012 278
2013 335
2014 423
2015 447
2016 536
2017 564
2018 695
2019 805
2020 950
2021 1051
2022 989
2023 951
2024 345

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Search Results

8,180 results

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Page 1
Autophagy and Senescence: The Molecular Mechanisms and Implications in Liver Diseases.
Li Q, Lin Y, Liang G, Xiao N, Zhang H, Yang X, Yang J, Liu A. Li Q, et al. Int J Mol Sci. 2023 Nov 28;24(23):16880. doi: 10.3390/ijms242316880. Int J Mol Sci. 2023. PMID: 38069199 Free PMC article. Review.
Autophagy can promote and delay cellular senescence under different contexts. This review decodes the roles of autophagy and senescence in multiple liver diseases to achieve a better understanding of the regulatory mechanisms and implications of aut …
Autophagy can promote and delay cellular senescence under different contexts. This review decodes the roles of autophagy …
Autophagy and senescence in cancer therapy.
Patel NH, Bloukh S, Alwohosh E, Alhesa A, Saleh T, Gewirtz DA. Patel NH, et al. Adv Cancer Res. 2021;150:1-74. doi: 10.1016/bs.acr.2021.01.002. Epub 2021 Mar 12. Adv Cancer Res. 2021. PMID: 33858594 Review.
While apoptosis represents the most desirable outcome, tumor cells can alternatively undergo autophagy and senescence. Both autophagy and senescence have the potential to make complex contributions to tumor cell survival via both cell autonomous and ce …
While apoptosis represents the most desirable outcome, tumor cells can alternatively undergo autophagy and senescence. Both …
Autophagy and senescence: A new insight in selected human diseases.
Rajendran P, Alzahrani AM, Hanieh HN, Kumar SA, Ben Ammar R, Rengarajan T, Alhoot MA. Rajendran P, et al. J Cell Physiol. 2019 Dec;234(12):21485-21492. doi: 10.1002/jcp.28895. Epub 2019 May 29. J Cell Physiol. 2019. PMID: 31144309 Review.
However, it is yet to be proven whether autophagy has a positive or negative impact on senescence. It is known that elevated levels of autophagy induce cell death, whereas inadequate autophagy can trigger cellular senescence. ...Therefore, this …
However, it is yet to be proven whether autophagy has a positive or negative impact on senescence. It is known that elevated l …
Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis.
Yamamoto-Imoto H, Minami S, Shioda T, Yamashita Y, Sakai S, Maeda S, Yamamoto T, Oki S, Takashima M, Yamamuro T, Yanagawa K, Edahiro R, Iwatani M, So M, Tokumura A, Abe T, Imamura R, Nonomura N, Okada Y, Ayer DE, Ogawa H, Hara E, Takabatake Y, Isaka Y, Nakamura S, Yoshimori T. Yamamoto-Imoto H, et al. Cell Rep. 2022 Mar 1;38(9):110444. doi: 10.1016/j.celrep.2022.110444. Cell Rep. 2022. PMID: 35235784 Free article.
Accumulation of senescent cells affects organismal aging and the prevalence of age-associated disease. ...Here, we identify the transcription factor, MondoA, as a regulator of cellular senescence, autophagy, and mitochondrial homeostasis. MondoA protec …
Accumulation of senescent cells affects organismal aging and the prevalence of age-associated disease. ...Here, we identify th …
Autophagy prevents microglial senescence.
Amin S, Liu B, Gan L. Amin S, et al. Nat Cell Biol. 2023 Jul;25(7):923-925. doi: 10.1038/s41556-023-01168-y. Nat Cell Biol. 2023. PMID: 37308635 No abstract available.
Autophagy and senescence: Insights from normal and cancer stem cells.
Talukdar S, Das SK, Emdad L, Fisher PB. Talukdar S, et al. Adv Cancer Res. 2021;150:147-208. doi: 10.1016/bs.acr.2021.01.005. Epub 2021 Mar 30. Adv Cancer Res. 2021. PMID: 33858596 Review.
Considering its critical function in regulating the metabolic state of stem cells, autophagy plays a dual role in the regulation of normal and cancer stem cell senescence, and cellular responses to various therapeutic strategies. The relationships between autopha …
Considering its critical function in regulating the metabolic state of stem cells, autophagy plays a dual role in the regulation of n …
Autophagy at the intersection of aging, senescence, and cancer.
Cassidy LD, Narita M. Cassidy LD, et al. Mol Oncol. 2022 Sep;16(18):3259-3275. doi: 10.1002/1878-0261.13269. Epub 2022 Jul 9. Mol Oncol. 2022. PMID: 35689420 Free PMC article. Review.
It fulfills essential roles in quality controlling cellular constituents and in energy homeostasis. Basal autophagy is also widely accepted to provide a protective role in aging and aging-related disorders, and its decline with age might precipitate the onset …
It fulfills essential roles in quality controlling cellular constituents and in energy homeostasis. Basal autophagy is also widely ac …
Autophagy and senescence, converging roles in pathophysiology as seen through mouse models.
Young ARJ, Cassidy LD, Narita M. Young ARJ, et al. Adv Cancer Res. 2021;150:113-145. doi: 10.1016/bs.acr.2021.02.001. Epub 2021 Mar 8. Adv Cancer Res. 2021. PMID: 33858595 Review.
Both senescence and autophagy have been strongly linked to aging and also cancer development. ...Whereas senescent cells are known to accumulate in our bodies with age. Herein we review evidence from some elegant genetic mouse models linking senesce …
Both senescence and autophagy have been strongly linked to aging and also cancer development. ...Whereas senescent …
Autophagy and Immune Senescence.
Zhang H, Puleston DJ, Simon AK. Zhang H, et al. Trends Mol Med. 2016 Aug;22(8):671-686. doi: 10.1016/j.molmed.2016.06.001. Epub 2016 Jul 7. Trends Mol Med. 2016. PMID: 27395769 Review.
With extension of the average lifespan, aging has become a heavy burden in society. Immune senescence is a key risk factor for many age-related diseases such as cancer and increased infections in the elderly, and hence has elicited much attention in recent years. .. …
With extension of the average lifespan, aging has become a heavy burden in society. Immune senescence is a key risk factor for …
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis.
Zhang Y, Huang W, Zheng Z, Wang W, Yuan Y, Hong Q, Lin J, Li X, Meng Y. Zhang Y, et al. Free Radic Biol Med. 2021 Apr;166:116-127. doi: 10.1016/j.freeradbiomed.2021.02.013. Epub 2021 Feb 17. Free Radic Biol Med. 2021. PMID: 33609723
Cigarette smoke (CS) is a strong risk factor for IPF and it is also a pro-senescent factor. Here we aimed to investigate whether and how CS induces AT2 cells senescence via a SIRT1/autophagy dependent pathway. ...Consequently, CS-inactivated SIRT1 promoted …
Cigarette smoke (CS) is a strong risk factor for IPF and it is also a pro-senescent factor. Here we aimed to investigate whether and …
8,180 results

Searches related to "autophagy senescence"