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Items: 1 to 20 of 41


Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.

Wang DY, Kosowan J, Samsom J, Leung L, Zhang KL, Li YX, Xiong Y, Jin J, Petronis A, Oh G, Wong AHC.

Acta Pharmacol Sin. 2018 May;39(5):866-874. doi: 10.1038/aps.2017.190. Epub 2018 Feb 8.


Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome.

Oh E, Jeremian R, Oh G, Groot D, Susic M, Lee K, Foy K, Laird PW, Petronis A, Labrie V.

Sci Rep. 2017 Jan 31;7:41843. doi: 10.1038/srep41843.


Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging.

Labrie V, Buske OJ, Oh E, Jeremian R, Ptak C, Gasiūnas G, Maleckas A, Petereit R, Žvirbliene A, Adamonis K, Kriukienė E, Koncevičius K, Gordevičius J, Nair A, Zhang A, Ebrahimi S, Oh G, Šikšnys V, Kupčinskas L, Brudno M, Petronis A.

Nat Struct Mol Biol. 2016 Jun;23(6):566-73. doi: 10.1038/nsmb.3227. Epub 2016 May 9.


Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28.

Zhang M, Xi Z, Ghani M, Jia P, Pal M, Werynska K, Moreno D, Sato C, Liang Y, Robertson J, Petronis A, Zinman L, Rogaeva E.

J Neurol Neurosurg Psychiatry. 2016 Nov;87(11):1268-1270. doi: 10.1136/jnnp-2016-313592. Epub 2016 May 6. No abstract available.


Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.

Gagliano SA, Ptak C, Mak DYF, Shamsi M, Oh G, Knight J, Boutros PC, Petronis A.

Am J Hum Genet. 2016 May 5;98(5):956-962. doi: 10.1016/j.ajhg.2016.03.006. Epub 2016 Apr 14.


High Precision DNA Modification Analysis of HCG9 in Major Psychosis.

Pal M, Ebrahimi S, Oh G, Khare T, Zhang A, Kaminsky ZA, Wang SC, Petronis A.

Schizophr Bull. 2016 Jan;42(1):170-7. doi: 10.1093/schbul/sbv079. Epub 2015 Jun 15.


DNA unmethylome profiling by covalent capture of CpG sites.

Kriukienė E, Labrie V, Khare T, Urbanavičiūtė G, Lapinaitė A, Koncevičius K, Li D, Wang T, Pai S, Ptak C, Gordevičius J, Wang SC, Petronis A, Klimašauskas S.

Nat Commun. 2013;4:2190. doi: 10.1038/ncomms3190.


Validating reference genes within a mouse model system of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity.

Prokopec SD, Buchner NB, Fox NS, Chong LC, Mak DY, Watson JD, Petronis A, Pohjanvirta R, Boutros PC.

Chem Biol Interact. 2013 Sep 5;205(1):63-71. doi: 10.1016/j.cbi.2013.06.008. Epub 2013 Jun 19.


Quantitative leukocyte BDNF promoter methylation analysis in bipolar disorder.

Strauss JS, Khare T, De Luca V, Jeremian R, Kennedy JL, Vincent JB, Petronis A.

Int J Bipolar Disord. 2013 Dec 30;1:28. doi: 10.1186/2194-7511-1-28. eCollection 2013.


5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.

Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, Wong AH, Blencowe BJ, Wang SC, Kapranov P, Kustra R, Labrie V, Klimasauskas S, Petronis A.

Nat Struct Mol Biol. 2012 Oct;19(10):1037-43. doi: 10.1038/nsmb.2372. Epub 2012 Sep 9.


Epigenetics of major psychosis: progress, problems and perspectives.

Labrie V, Pai S, Petronis A.

Trends Genet. 2012 Sep;28(9):427-35. doi: 10.1016/j.tig.2012.04.002. Epub 2012 May 21. Review.


Epigenetic markers of prostate cancer in plasma circulating DNA.

Cortese R, Kwan A, Lalonde E, Bryzgunova O, Bondar A, Wu Y, Gordevicius J, Park M, Oh G, Kaminsky Z, Tverkuviene J, Laurinavicius A, Jankevicius F, Sendorek DH, Haider S, Wang SC, Jarmalaite S, Laktionov P, Boutros PC, Petronis A.

Hum Mol Genet. 2012 Aug 15;21(16):3619-31. doi: 10.1093/hmg/dds192. Epub 2012 May 22.


A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.

Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J.

Nat Chem Biol. 2011 Jul 10;7(8):566-74. doi: 10.1038/nchembio.599. Erratum in: Nat Chem Biol. 2011 Sep;7(9):648. Nat Chem Biol. 2011;7(8):following 574.


Uropathogenic E. coli infection provokes epigenetic downregulation of CDKN2A (p16INK4A) in uroepithelial cells.

Tolg C, Sabha N, Cortese R, Panchal T, Ahsan A, Soliman A, Aitken KJ, Petronis A, Bägli DJ.

Lab Invest. 2011 Jun;91(6):825-36. doi: 10.1038/labinvest.2010.197. Epub 2011 Jan 17.


Understanding bipolar disorder: the epigenetic perspective.

Khare T, Pal M, Petronis A.

Curr Top Behav Neurosci. 2011;5:31-49. doi: 10.1007/7854_2010_64.


Epigenetics as a unifying principle in the aetiology of complex traits and diseases.

Petronis A.

Nature. 2010 Jun 10;465(7299):721-7. doi: 10.1038/nature09230.


Epigenetic approaches to psychiatric disorders.

Ptak C, Petronis A.

Dialogues Clin Neurosci. 2010;12(1):25-35. Review.


Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients.

Flanagan JM, Munoz-Alegre M, Henderson S, Tang T, Sun P, Johnson N, Fletcher O, Dos Santos Silva I, Peto J, Boshoff C, Narod S, Petronis A.

Hum Mol Genet. 2009 Apr 1;18(7):1332-42. doi: 10.1093/hmg/ddp033. Epub 2009 Jan 19.


Methylation SNaPshot: a method for the quantification of site-specific DNA methylation levels.

Kaminsky Z, Petronis A.

Methods Mol Biol. 2009;507:241-55. doi: 10.1007/978-1-59745-522-0_18.


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