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Andrographis Paniculata Ameliorates Insulin Resistance in High Fat Diet-fed Mice and 3T3-L1 Adipocytes (P21-074-19).

Chen HW, Chen CC.

Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz041.P21-074-19. doi: 10.1093/cdn/nzz041.P21-074-19. eCollection 2019 Jun.


Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia.

Zhang G, Jiang C, Xie N, Xu Y, Liu L, Liu N.

Biomed Pharmacother. 2019 Jun 17;117:109065. doi: 10.1016/j.biopha.2019.109065. [Epub ahead of print]


Acute oral toxicity evaluation of Andrographis paniculata-standardized first true leaf ethanolic extract.

Worasuttayangkurn L, Nakareangrit W, Kwangjai J, Sritangos P, Pholphana N, Watcharasit P, Rangkadilok N, Thiantanawat A, Satayavivad J.

Toxicol Rep. 2019 May 6;6:426-430. doi: 10.1016/j.toxrep.2019.05.003. eCollection 2019.


A review for the neuroprotective effects of andrographolide in the central nervous system.

Lu J, Ma Y, Wu J, Huang H, Wang X, Chen Z, Chen J, He H, Huang C.

Biomed Pharmacother. 2019 Jun 7;117:109078. doi: 10.1016/j.biopha.2019.109078. [Epub ahead of print] Review.


Andrographolide: A natural product template for the generation of structurally and biologically diverse diterpenes.

Kandanur SGS, Tamang N, Golakoti NR, Nanduri S.

Eur J Med Chem. 2019 Aug 15;176:513-533. doi: 10.1016/j.ejmech.2019.05.022. Epub 2019 May 11. Review.


Bioavailability of the diterpenoid 14-deoxy-11,12-didehydroandrographolide in rats and up-regulation of hepatic drug-metabolizing enzyme and drug transporter expression.

Yen CC, Liu YT, Lin YJ, Yang YC, Chen CC, Yao HT, Chen HW, Lii CK.

Phytomedicine. 2019 Jan 24;61:152841. doi: 10.1016/j.phymed.2019.152841. [Epub ahead of print]


Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities.

Xu Y, Wei H, Wang J, Wang W, Gao J.

Bioorg Med Chem. 2019 Jun 1;27(11):2209-2219. doi: 10.1016/j.bmc.2019.04.025. Epub 2019 Apr 16.


A double-blind, randomized, placebo-controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis.

Hancke JL, Srivastav S, Cáceres DD, Burgos RA.

Phytother Res. 2019 May;33(5):1469-1479. doi: 10.1002/ptr.6339. Epub 2019 Apr 10.


Multiple modulatory activities of Andrographis paniculata on immune responses and xenograft growth in esophageal cancer preclinical models.

Yue GG, Li L, Lee JK, Kwok HF, Wong EC, Li M, Fung KP, Yu J, Chan AW, Chiu PW, Lau CB.

Phytomedicine. 2019 Mar 12:152886. doi: 10.1016/j.phymed.2019.152886. [Epub ahead of print]


A standardised Andrographis paniculata Burm. Nees aqueous extract prevents Lipopolysaccharide-induced cognitive deficits through suppression of inflammatory cytokines and oxidative stress mediators.

Sani D, Khatab NIO, Kirby BP, Yong A, Hasan S, Basri H, Stanslas J.

J Adv Res. 2018 Nov 30;16:87-97. doi: 10.1016/j.jare.2018.11.005. eCollection 2019 Mar.


An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache.

Moscano F, Guiducci M, Maltoni L, Striano P, Ledda MG, Zoroddu F, Raucci U, Villa MP, Parisi P.

Ital J Pediatr. 2019 Mar 12;45(1):36. doi: 10.1186/s13052-019-0624-z.


Efficacy of Several Plants Extracts on the Tunneling Activity and Survival of Subterranean Termites (Coptotermes gestroi and Globitermes sulphureus).

Bakaruddin NH, Ab Majid AH.

Trop Life Sci Res. 2019 Jan;30(1):33-56. doi: 10.21315/tlsr2019.30.1.3. Epub 2019 Jan 31.


Structural and antioxidant studies of a new arabinoxylan from green stem Andrographis paniculata (Kalmegh).

Maity GN, Maity P, Dasgupta A, Acharya K, Dalai S, Mondal S.

Carbohydr Polym. 2019 May 15;212:297-303. doi: 10.1016/j.carbpol.2019.02.051. Epub 2019 Feb 18.


Andrographolide and its potent derivative exhibit anticancer effects against imatinib-resistant chronic myeloid leukemia cells by downregulating the Bcr-Abl oncoprotein.

Liao HC, Chou YJ, Lin CC, Liu SH, Oswita A, Huang YL, Wang YL, Syu JL, Sun CM, Leu CM, Lin CH, Fu SL.

Biochem Pharmacol. 2019 May;163:308-320. doi: 10.1016/j.bcp.2019.02.028. Epub 2019 Feb 26.


Andrographolide induces DNA damage in prostate cancer cells.

Forestier-Román IS, López-Rivas A, Sánchez-Vázquez MM, Rohena-Rivera K, Nieves-Burgos G, Ortiz-Zuazaga H, Torres-Ramos CA, Martínez-Ferrer M.

Oncotarget. 2019 Feb 1;10(10):1085-1101. doi: 10.18632/oncotarget.26628. eCollection 2019 Feb 1.


Anti-dengue activity of Andrographis paniculata extracts and quantification of dengue viral inhibition by SYBR green reverse transcription polymerase chain reaction.

Ramalingam S, Karupannan S, Padmanaban P, Vijayan S, Sheriff K, Palani G, Krishnasamy KK.

Ayu. 2018 Apr-Jun;39(2):87-91. doi: 10.4103/ayu.AYU_144_17.


Ovicidal and larvicidal effects of extracts from leaves of Andrographis paniculata (Burm. f.) Wall.ex Nees against field isolates of human hookworm (Ancylostoma duodenale).

Banerjee T, Singh A, Kumar S, Dhanani T, Gajbhiye NA, Koley TK, Maurya A, Filgona J.

J Ethnopharmacol. 2019 May 10;235:489-500. doi: 10.1016/j.jep.2019.02.021. Epub 2019 Feb 11.


Preparative Separation of Diterpene Lactones and Flavones from Andrographis paniculate Using Off-Line Two-Dimensional High-Speed Counter-Current Chromatography.

Sun X, Yan H, Zhang Y, Wang X, Qin D, Yu J.

Molecules. 2019 Feb 11;24(3). pii: E620. doi: 10.3390/molecules24030620.


Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-кB Pathway in Bladder Cancer Cells.

Deng Y, Bi R, Guo H, Yang J, Du Y, Wang C, Wei W.

Int J Biol Sci. 2019 Jan 24;15(3):688-700. doi: 10.7150/ijbs.30847. eCollection 2019.


Evaluation of andrographolide-based analogs derived from Andrographis paniculata against Mythimna separata Walker and Tetranychus cinnabarinus Boisduval.

Xu M, Xu J, Hao M, Zhang K, Lv M, Xu H.

Bioorg Chem. 2019 May;86:28-33. doi: 10.1016/j.bioorg.2019.01.020. Epub 2019 Jan 17.


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