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Lancet Infect Dis. 2016 Dec;16(12):e288-e303. doi: 10.1016/S1473-3099(16)30402-9. Epub 2016 Nov 2.

New WHO recommendations on intraoperative and postoperative measures for surgical site infection prevention: an evidence-based global perspective.

Author information

1
Infection Prevention and Control Global Unit, Service Delivery and Safety, WHO, Geneva, Switzerland. Electronic address: allegranzib@who.int.
2
Infection Prevention and Control Global Unit, Service Delivery and Safety, WHO, Geneva, Switzerland.
3
Institute of Hygiene and Environmental Medicine, Charité-University Medicine, Berlin, Germany.
4
Department of Surgery, Academic Medical Center Amsterdam, Amsterdam, Netherlands.
5
OASIS Global, Cincinnati, OH, USA.
6
Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
7
Infection Control Programme, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
8
Department of Surgery, University of Washington, Seattle, WA, USA.
9
Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
10
Parc Taulí Hospital Universitari, Barcelona, Spain.
11
Infection Control Programme, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland; WHO Collaborating Centre on Patient Safety (Infection Control and Improving Practices), University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
12
OASIS Global, Cincinnati, OH, USA; University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Abstract

Surgical site infections (SSIs) are the most common health-care-associated infections in developing countries, but they also represent a substantial epidemiological burden in high-income countries. The prevention of these infections is complex and requires the integration of a range of preventive measures before, during, and after surgery. No international guidelines are available and inconsistencies in the interpretation of evidence and recommendations in national guidelines have been identified. Considering the prevention of SSIs as a priority for patient safety, WHO has developed evidence-based and expert consensus-based recommendations on the basis of an extensive list of preventive measures. We present in this Review 16 recommendations specific to the intraoperative and postoperative periods. The WHO recommendations were developed with a global perspective and they take into account the balance between benefits and harms, the evidence quality level, cost and resource use implications, and patient values and preferences.

PMID:
27816414
DOI:
10.1016/S1473-3099(16)30402-9
[Indexed for MEDLINE]

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