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Items: 12

1.

Hepatocyte autotaxin expression promotes liver fibrosis and cancer.

Kaffe E, Katsifa A, Xylourgidis N, Ninou I, Zannikou M, Harokopos V, Foka P, Dimitriadis A, Evangelou K, Moulas AN, Georgopoulou U, Gorgoulis VG, Dalekos GN, Aidinis V.

Hepatology. 2016 Dec 16. doi: 10.1002/hep.28973. [Epub ahead of print]

PMID:
27981605
2.

Computer Aided Drug Design Approaches for Identification of Novel Autotaxin (ATX) Inhibitors.

Vrontaki E, Melagraki G, Kaffe E, Mavromoustakos T, Kokotos G, Aidinis V, Afantitis A.

Curr Med Chem. 2016;23(17):1708-24. Review.

PMID:
26997151
3.

The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life.

Katsifa A, Kaffe E, Nikolaidou-Katsaridou N, Economides AN, Newbigging S, McKerlie C, Aidinis V.

PLoS One. 2015 Nov 16;10(11):e0143083. doi: 10.1371/journal.pone.0143083.

4.

Autotaxin and Endotoxin-Induced Acute Lung Injury.

Mouratis MA, Magkrioti C, Oikonomou N, Katsifa A, Prestwich GD, Kaffe E, Aidinis V.

PLoS One. 2015 Jul 21;10(7):e0133619. doi: 10.1371/journal.pone.0133619.

5.

Non-cell autonomous and non-catalytic activities of ATX in the developing brain.

Greenman R, Gorelik A, Sapir T, Baumgart J, Zamor V, Segal-Salto M, Levin-Zaidman S, Aidinis V, Aoki J, Nitsch R, Vogt J, Reiner O.

Front Neurosci. 2015 Mar 4;9:53. doi: 10.3389/fnins.2015.00053.

6.

Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer.

Barbayianni E, Kaffe E, Aidinis V, Kokotos G.

Prog Lipid Res. 2015 Apr;58:76-96. doi: 10.1016/j.plipres.2015.02.001. Review.

PMID:
25704398
7.

Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.

Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, Kelly EA, Jarjour NN, Chun J, Prestwich GD, Kaffe E, Ninou I, Aidinis V, Morris AJ, Smyth SS, Ackerman SJ, Natarajan V, Christman JW.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):928-40. doi: 10.1164/rccm.201306-1014OC.

8.

A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis.

Nikitopoulou I, Kaffe E, Sevastou I, Sirioti I, Samiotaki M, Madan D, Prestwich GD, Aidinis V.

PLoS One. 2013 Jul 29;8(7):e70941. doi: 10.1371/journal.pone.0070941.

9.

Lysoglycerophospholipids in chronic inflammatory disorders: the PLA(2)/LPC and ATX/LPA axes.

Sevastou I, Kaffe E, Mouratis MA, Aidinis V.

Biochim Biophys Acta. 2013 Jan;1831(1):42-60. doi: 10.1016/j.bbalip.2012.07.019. Review.

PMID:
22867755
10.

Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.

Oikonomou N, Mouratis MA, Tzouvelekis A, Kaffe E, Valavanis C, Vilaras G, Karameris A, Prestwich GD, Bouros D, Aidinis V.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):566-74. doi: 10.1165/rcmb.2012-0004OC.

PMID:
22744859
11.

Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis.

Nikitopoulou I, Oikonomou N, Karouzakis E, Sevastou I, Nikolaidou-Katsaridou N, Zhao Z, Mersinias V, Armaka M, Xu Y, Masu M, Mills GB, Gay S, Kollias G, Aidinis V.

J Exp Med. 2012 May 7;209(5):925-33. doi: 10.1084/jem.20112012.

12.

ATX expression and LPA signalling are vital for the development of the nervous system.

Fotopoulou S, Oikonomou N, Grigorieva E, Nikitopoulou I, Paparountas T, Thanassopoulou A, Zhao Z, Xu Y, Kontoyiannis DL, Remboutsika E, Aidinis V.

Dev Biol. 2010 Mar 15;339(2):451-64. doi: 10.1016/j.ydbio.2010.01.007.

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