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Items: 1 to 20 of 109

1.

Glucocorticoid Resistance in Acute Lymphoblastic Leukemia: BIM Finally.

Brown JA, Ferrando A.

Cancer Cell. 2018 Dec 10;34(6):869-871. doi: 10.1016/j.ccell.2018.11.011.

PMID:
30537507
2.

Can one target T-cell ALL?

Ferrando A.

Best Pract Res Clin Haematol. 2018 Dec;31(4):361-366. doi: 10.1016/j.beha.2018.10.001. Epub 2018 Oct 17. Review.

PMID:
30466748
3.

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia.

Kourtis N, Lazaris C, Hockemeyer K, Balandrán JC, Jimenez AR, Mullenders J, Gong Y, Trimarchi T, Bhatt K, Hu H, Shrestha L, Ambesi-Impiombato A, Kelliher M, Paietta E, Chiosis G, Guzman ML, Ferrando AA, Tsirigos A, Aifantis I.

Nat Med. 2018 Aug;24(8):1157-1166. doi: 10.1038/s41591-018-0105-8. Epub 2018 Jul 23.

PMID:
30038221
4.

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Ambesi-Impiombato A, Sánchez-Martín M, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando AA.

Cancer Cell. 2018 Jul 9;34(1):136-147.e6. doi: 10.1016/j.ccell.2018.06.003.

PMID:
29990496
5.

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.

Furness CL, Mansur MB, Weston VJ, Ermini L, van Delft FW, Jenkinson S, Gale R, Harrison CJ, Pombo-de-Oliveira MS, Sanchez-Martin M, Ferrando AA, Kearns P, Titley I, Ford AM, Potter NE, Greaves M.

Leukemia. 2018 Sep;32(9):1984-1993. doi: 10.1038/s41375-018-0046-8. Epub 2018 Mar 20.

6.

RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.

Cortes JR, Ambesi-Impiombato A, Couronné L, Quinn SA, Kim CS, da Silva Almeida AC, West Z, Belver L, Martin MS, Scourzic L, Bhagat G, Bernard OA, Ferrando AA, Palomero T.

Cancer Cell. 2018 Feb 12;33(2):259-273.e7. doi: 10.1016/j.ccell.2018.01.001. Epub 2018 Feb 2.

PMID:
29398449
7.

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia.

Tzoneva G, Dieck CL, Oshima K, Ambesi-Impiombato A, Sánchez-Martín M, Madubata CJ, Khiabanian H, Yu J, Waanders E, Iacobucci I, Sulis ML, Kato M, Koh K, Paganin M, Basso G, Gastier-Foster JM, Loh ML, Kirschner-Schwabe R, Mullighan CG, Rabadan R, Ferrando AA.

Nature. 2018 Jan 25;553(7689):511-514. doi: 10.1038/nature25186. Epub 2018 Jan 17.

8.

Targeted cellular immunotherapy for T cell malignancies.

Palomero T, Ferrando A.

Nat Med. 2017 Dec 7;23(12):1402-1403. doi: 10.1038/nm.4458. No abstract available.

9.

Leukemia-specific delivery of mutant NOTCH1 targeted therapy.

Roti G, Qi J, Kitara S, Sanchez-Martin M, Saur Conway A, Varca AC, Su A, Wu L, Kung AL, Ferrando AA, Bradner JE, Stegmaier K.

J Exp Med. 2018 Jan 2;215(1):197-216. doi: 10.1084/jem.20151778. Epub 2017 Nov 20.

10.

Pharmacological inhibition of the transcription factor PU.1 in leukemia.

Antony-Debré I, Paul A, Leite J, Mitchell K, Kim HM, Carvajal LA, Todorova TI, Huang K, Kumar A, Farahat AA, Bartholdy B, Narayanagari SR, Chen J, Ambesi-Impiombato A, Ferrando AA, Mantzaris I, Gavathiotis E, Verma A, Will B, Boykin DW, Wilson WD, Poon GM, Steidl U.

J Clin Invest. 2017 Dec 1;127(12):4297-4313. doi: 10.1172/JCI92504. Epub 2017 Oct 30.

11.

Clonal evolution in leukemia.

Ferrando AA, López-Otín C.

Nat Med. 2017 Oct 6;23(10):1135-1145. doi: 10.1038/nm.4410. [Epub ahead of print] Review.

PMID:
28985206
12.

Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.

Fabbri G, Holmes AB, Viganotti M, Scuoppo C, Belver L, Herranz D, Yan XJ, Kieso Y, Rossi D, Gaidano G, Chiorazzi N, Ferrando AA, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2911-E2919. doi: 10.1073/pnas.1702564114. Epub 2017 Mar 17.

13.

Multivalent Small-Molecule Pan-RAS Inhibitors.

Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR.

Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006.

14.

Synergistic antileukemic therapies in NOTCH1-induced T-ALL.

Sanchez-Martin M, Ambesi-Impiombato A, Qin Y, Herranz D, Bansal M, Girardi T, Paietta E, Tallman MS, Rowe JM, De Keersmaecker K, Califano A, Ferrando AA.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2006-2011. doi: 10.1073/pnas.1611831114. Epub 2017 Feb 7.

15.

The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia.

Sanchez-Martin M, Ferrando A.

Blood. 2017 Mar 2;129(9):1124-1133. doi: 10.1182/blood-2016-09-692582. Epub 2017 Jan 23. Review.

16.

Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.

Abate F, da Silva-Almeida AC, Zairis S, Robles-Valero J, Couronne L, Khiabanian H, Quinn SA, Kim MY, Laginestra MA, Kim C, Fiore D, Bhagat G, Piris MA, Campo E, Lossos IS, Bernard OA, Inghirami G, Pileri S, Bustelo XR, Rabadan R, Ferrando AA, Palomero T.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):764-769. doi: 10.1073/pnas.1608839114. Epub 2017 Jan 6.

17.

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia.

Oshima K, Khiabanian H, da Silva-Almeida AC, Tzoneva G, Abate F, Ambesi-Impiombato A, Sanchez-Martin M, Carpenter Z, Penson A, Perez-Garcia A, Eckert C, Nicolas C, Balbin M, Sulis ML, Kato M, Koh K, Paganin M, Basso G, Gastier-Foster JM, Devidas M, Loh ML, Kirschner-Schwabe R, Palomero T, Rabadan R, Ferrando AA.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11306-11311. Epub 2016 Sep 21.

18.

The genetics and mechanisms of T cell acute lymphoblastic leukaemia.

Belver L, Ferrando A.

Nat Rev Cancer. 2016 Jul 25;16(8):494-507. doi: 10.1038/nrc.2016.63. Review.

PMID:
27451956
19.

Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1.

Ann EJ, Kim MY, Yoon JH, Ahn JS, Jo EH, Lee HJ, Lee HW, Kang HG, Choi DW, Chun KH, Lee JS, Choi CY, Ferrando AA, Lee K, Park HS.

Cancer Res. 2016 Aug 15;76(16):4728-40. doi: 10.1158/0008-5472.CAN-15-3310. Epub 2016 Jun 22.

20.

MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling.

Soria-Valles C, Gutiérrez-Fernández A, Osorio FG, Carrero D, Ferrando AA, Colado E, Fernández-García MS, Bonzon-Kulichenko E, Vázquez J, Fueyo A, López-Otín C.

J Immunol. 2016 Jul 1;197(1):296-302. doi: 10.4049/jimmunol.1600094. Epub 2016 Jun 3.

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