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Items: 15

1.

Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.

Shirakawa J, Fernandez M, Takatani T, El Ouaamari A, Jungtrakoon P, Okawa ER, Zhang W, Yi P, Doria A, Kulkarni RN.

Cell Metab. 2017 Apr 4;25(4):868-882.e5. doi: 10.1016/j.cmet.2017.02.004. Epub 2017 Mar 9.

2.

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.

Boucher J, Softic S, El Ouaamari A, Krumpoch MT, Kleinridders A, Kulkarni RN, O'Neill BT, Kahn CR.

Diabetes. 2016 Aug;65(8):2201-13. doi: 10.2337/db16-0212. Epub 2016 May 13.

3.

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas.

Singhal G, Fisher FM, Chee MJ, Tan TG, El Ouaamari A, Adams AC, Najarian R, Kulkarni RN, Benoist C, Flier JS, Maratos-Flier E.

PLoS One. 2016 Feb 12;11(2):e0148252. doi: 10.1371/journal.pone.0148252. eCollection 2016.

4.

SerpinB1 Promotes Pancreatic β Cell Proliferation.

El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN.

Cell Metab. 2016 Jan 12;23(1):194-205. doi: 10.1016/j.cmet.2015.12.001. Epub 2015 Dec 15.

5.

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN.

Cell Metab. 2015 Aug 4;22(2):239-52. doi: 10.1016/j.cmet.2015.07.015.

6.

Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.

El Ouaamari A, Zhou JY, Liew CW, Shirakawa J, Dirice E, Gedeon N, Kahraman S, De Jesus DF, Bhatt S, Kim JS, Clauss TR, Camp DG 2nd, Smith RD, Qian WJ, Kulkarni RN.

J Proteome Res. 2015 Aug 7;14(8):3111-3122. doi: 10.1021/acs.jproteome.5b00587. Epub 2015 Jul 30.

7.

Anti-inflammatory natural products.

Yang Y, Hou L, El Ouaamari A, Xin L.

Mediators Inflamm. 2015;2015:608613. doi: 10.1155/2015/608613. Epub 2015 Apr 27. No abstract available.

8.

The Polycomb protein, Bmi1, regulates insulin sensitivity.

Cannon CE, Titchenell PM, Groff DN, El Ouaamari A, Kulkarni RN, Birnbaum MJ, Stoffers DA.

Mol Metab. 2014 Aug 27;3(8):794-802. doi: 10.1016/j.molmet.2014.08.002. eCollection 2014 Nov.

9.

Nonalcoholic Fatty liver disease: its mechanisms and complications.

El Ouaamari A, Minehira K.

Int J Endocrinol. 2013;2013:969748. doi: 10.1155/2013/969748. Epub 2013 Oct 2. No abstract available.

10.

Soluble factors secreted by T cells promote β-cell proliferation.

Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus DF, Teo AK, Hu J, Kawamori D, Gaglia JL, Mathis D, Kulkarni RN.

Diabetes. 2014 Jan;63(1):188-202. doi: 10.2337/db13-0204. Epub 2013 Oct 2.

11.

Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.

Ræder H, McAllister FE, Tjora E, Bhatt S, Haldorsen I, Hu J, Willems SM, Vesterhus M, El Ouaamari A, Liu M, Ræder MB, Immervoll H, Hoem D, Dimcevski G, Njølstad PR, Molven A, Gygi SP, Kulkarni RN.

Diabetes. 2014 Jan;63(1):259-69. doi: 10.2337/db13-1012. Epub 2013 Sep 23.

12.

Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).

Ræder H, Vesterhus M, El Ouaamari A, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, Njølstad PR, Kahn CR, Kulkarni RN.

PLoS One. 2013;8(4):e60229. doi: 10.1371/journal.pone.0060229. Epub 2013 Apr 2.

13.

Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states.

El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN.

Cell Rep. 2013 Feb 21;3(2):401-10. doi: 10.1016/j.celrep.2013.01.007. Epub 2013 Jan 31. Erratum in: Cell Rep. 2013 Mar 28;3(3):969.

14.

Rosiglitazone promotes PPARγ-dependent and -independent alterations in gene expression in mouse islets.

Welters HJ, El Ouaamari A, Kawamori D, Meyer J, Hu J, Smith DM, Kulkarni RN.

Endocrinology. 2012 Oct;153(10):4593-9. Epub 2012 Jul 17.

15.

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells.

El Ouaamari A, Baroukh N, Martens GA, Lebrun P, Pipeleers D, van Obberghen E.

Diabetes. 2008 Oct;57(10):2708-17. doi: 10.2337/db07-1614. Epub 2008 Jun 30.

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