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A Case-Control Study of ABCB1, ABCB6, and ABCG1 Polymorphisms and Schizophrenia in a Han Chinese Population.
Ma G, Huang X, Bi Y, Xu F, Niu W, Ren D, Sun Q, Guo Z, Yuan R, Yuan F, Wu X, Yang F, Wang L, Li W, He L, Yu T, Li X, Liu J, He G. Ma G, et al. Neuropsychobiology. 2019;78(3):113-117. doi: 10.1159/000496295. Epub 2019 Jun 12. Neuropsychobiology. 2019. PMID: 31189171
BACKGROUND: Schizophrenia (SCZ) is a complex, heritable, and devastating psychiatric disorder. ...CONCLUSIONS: Our findings support an association between ABCG1 polymorphism and SCZ in a Han Chinese population....
BACKGROUND: Schizophrenia (SCZ) is a complex, heritable, and devastating psychiatric disorder. ...CONCLUSIONS: Our findings support a …
Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes.
Zhou W, Sun J, Huai C, Liu Y, Chen L, Yi Z, Lv Q, Song C, Zhu W, Liu C, Weng S, Wu H, Sun Y, Zhang R, Wu L, Li M, Zhu J, Zhang Y, Wei M, Guo Y, Huang S, Zhang N, Shen R, Zhang Y, Du H, Huang H, He L, Sun X, Shen L, Qin S. Zhou W, et al. Mol Psychiatry. 2022 Dec;27(12):5195-5205. doi: 10.1038/s41380-022-01759-5. Epub 2022 Sep 5. Mol Psychiatry. 2022. PMID: 36065016
In this study, we performed genome-wide, whole-exome sequencing (WES) and epigenome-wide association studies in schizophrenia (SCZ) patients with or without APs-induced Mets to find the underlying mechanisms, followed by in vitro and in vivo functional validations. ...Besi …
In this study, we performed genome-wide, whole-exome sequencing (WES) and epigenome-wide association studies in schizophrenia (SCZ) p …
Increased ABCA1 (ATP-Binding Cassette Transporter A1)-Specific Cholesterol Efflux Capacity in Schizophrenia.
Luquain-Costaz C, Kockx M, Anastasius M, Chow V, Kontush A, Jessup W, Kritharides L. Luquain-Costaz C, et al. Arterioscler Thromb Vasc Biol. 2020 Nov;40(11):2728-2737. doi: 10.1161/ATVBAHA.120.314847. Epub 2020 Sep 10. Arterioscler Thromb Vasc Biol. 2020. PMID: 32907370 Free article.
The removal of cholesterol from cells by HDL via specific ATP-binding cholesterol transporters is a major functional property of HDL, and its measurement as cholesterol efflux capacity (CEC) can predict cardiovascular risk. Whether HDL function is impaired in patients with sch …
The removal of cholesterol from cells by HDL via specific ATP-binding cholesterol transporters is a major functional property of HDL, and it …