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An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice.
Eyer L, Nougairède A, Uhlířová M, Driouich JS, Zouharová D, Valdés JJ, Haviernik J, Gould EA, De Clercq E, de Lamballerie X, Ruzek D. Eyer L, et al. Among authors: zouharova d. J Virol. 2019 Jul 30;93(16):e00367-19. doi: 10.1128/JVI.00367-19. Print 2019 Aug 15. J Virol. 2019. PMID: 31142664 Free PMC article.
Hyaluronic Acid Surface Modified Liposomes Prepared via Orthogonal Aminoxy Coupling: Synthesis of Nontoxic Aminoxylipids Based on Symmetrically α-Branched Fatty Acids, Preparation of Liposomes by Microfluidic Mixing, and Targeting to Cancer Cells Expressing CD44.
Bartheldyová E, Effenberg R, Mašek J, Procházka L, Knötigová PT, Kulich P, Hubatka F, Velínská K, Zelníčková J, Zouharová D, Fojtíková M, Hrebík D, Plevka P, Mikulík R, Miller AD, Macaulay S, Zyka D, Drož L, Raška M, Ledvina M, Turánek J. Bartheldyová E, et al. Among authors: zouharova d. Bioconjug Chem. 2018 Jul 18;29(7):2343-2356. doi: 10.1021/acs.bioconjchem.8b00311. Epub 2018 Jun 25. Bioconjug Chem. 2018. PMID: 29898364
Antiviral activities of 2,6-diaminopurine-based acyclic nucleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1).
Zouharova D, Lipenska I, Fojtikova M, Kulich P, Neca J, Slany M, Kovarcik K, Turanek-Knotigova P, Hubatka F, Celechovska H, Masek J, Koudelka S, Prochazka L, Eyer L, Plockova J, Bartheldyova E, Miller AD, Ruzek D, Raska M, Janeba Z, Turanek J. Zouharova D, et al. Vet Microbiol. 2016 Feb 29;184:84-93. doi: 10.1016/j.vetmic.2016.01.010. Epub 2016 Jan 18. Vet Microbiol. 2016. PMID: 26854349
Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness.
Eyer L, Kondo H, Zouharova D, Hirano M, Valdés JJ, Muto M, Kastl T, Kobayashi S, Haviernik J, Igarashi M, Kariwa H, Vaculovicova M, Cerny J, Kizek R, Kröger A, Lienenklaus S, Dejmek M, Nencka R, Palus M, Salat J, De Clercq E, Yoshii K, Ruzek D. Eyer L, et al. Among authors: zouharova d. J Virol. 2017 Oct 13;91(21):e01028-17. doi: 10.1128/JVI.01028-17. Print 2017 Nov 1. J Virol. 2017. PMID: 28814513 Free PMC article.