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Year Number of Results
1989 1
1993 1
1994 1
1995 1
1997 1
1998 2
1999 2
2000 1
2001 3
2002 1
2003 4
2004 3
2005 5
2006 11
2007 12
2008 17
2009 19
2010 20
2011 28
2012 32
2013 29
2014 32
2015 42
2016 31
2017 56
2018 50
2019 60
2020 74
2021 85
2022 91
2023 92
2024 30

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741 results

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Page 1
Efgartigimod improved health-related quality of life in generalized myasthenia gravis: results from a randomized, double-blind, placebo-controlled, phase 3 study (ADAPT).
Saccà F, Barnett C, Vu T, Peric S, Phillips GA, Zhao S, Qi CZ, Gelinas D, Chiroli S, Verschuuren JJGM. Saccà F, et al. J Neurol. 2023 Apr;270(4):2096-2105. doi: 10.1007/s00415-022-11517-w. Epub 2023 Jan 4. J Neurol. 2023. PMID: 36598575 Free PMC article. Clinical Trial.
HRQoL measures such as the Myasthenia Gravis Quality of Life 15-item revised (MG-QOL15r) and EuroQoL 5-Dimensions 5-Levels (EQ-5D-5L) are vital for evaluating the clinical benefit of therapeutic interventions in patients with MG, as they assess the burden of disease and th …
HRQoL measures such as the Myasthenia Gravis Quality of Life 15-item revised (MG-QOL15r) and EuroQoL 5-Dimensions 5-Levels (EQ-5D-5L) …
Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies.
Zhao N, Yang Y, Zhang L, Zhang Q, Balbuena L, Ungvari GS, Zang YF, Xiang YT. Zhao N, et al. CNS Neurosci Ther. 2021 Mar;27(3):270-279. doi: 10.1111/cns.13549. Epub 2020 Dec 28. CNS Neurosci Ther. 2021. PMID: 33372386 Free PMC article.

Different QOL measures varied in their association with quality of life, with the Parkinson's Disease Questionnaire-39 (PDQ-39) having the largest effect size (standard mean difference, SMD = -1.384, 95% CI: -1.607, -1.162, Z = 12.189, P < 0.001), followed by the Europe Qualit

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Different QOL measures varied in their association with quality of life, with the Parkinson's Disease Questionnaire-39 (PDQ-39) having the l …
Health-Related Quality of Life and Associated Factors among Oldest-Old in China.
Chen C, Liu GG, Shi QL, Sun Y, Zhang H, Wang MJ, Jia HP, Zhao YL, Yao Y. Chen C, et al. J Nutr Health Aging. 2020;24(3):330-338. doi: 10.1007/s12603-020-1327-2. J Nutr Health Aging. 2020. PMID: 32115616 Free PMC article.
PARTICIPANTS: 1,278 adults aged 80 years or older. METHODS: HRQoL was assessed by three-level EuroQol-5D scale (EQ-5D-3L) and a visual analogue scale (VAS). Demographic and health-related variables were analysed by estimating mean values and standard deviations for …
PARTICIPANTS: 1,278 adults aged 80 years or older. METHODS: HRQoL was assessed by three-level EuroQol-5D scale (EQ-5D-3L) and …
Pickle Juice Intervention for Cirrhotic Cramps Reduction: The PICCLES Randomized Controlled Trial.
Tapper EB, Salim N, Baki J, Zhao Z, Sundaram V, Patwardhan V, Nikirk SJ. Tapper EB, et al. Am J Gastroenterol. 2022 Jun 1;117(6):895-901. doi: 10.14309/ajg.0000000000001781. Epub 2022 Apr 13. Am J Gastroenterol. 2022. PMID: 35416793 Clinical Trial.
Secondary outcomes included the proportion of days with VAS-cramps <5, change in sleep quality, and global health-related quality of life measured using the EQ-5D. RESULTS: Overall, 74 patients completed the trial, aged 56.6 11.5 years, 54% male, 41% with ascites, 38% w …
Secondary outcomes included the proportion of days with VAS-cramps <5, change in sleep quality, and global health-related quality of life …
Circadian regulation of hippocampal function is disrupted with corticosteroid treatment.
Birnie MT, Claydon MDB, Troy O, Flynn BP, Yoshimura M, Kershaw YM, Zhao Z, Demski-Allen RCR, Barker GRI, Warburton EC, Bortolotto ZA, Lightman SL, Conway-Campbell BL. Birnie MT, et al. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2211996120. doi: 10.1073/pnas.2211996120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023133 Free PMC article.
Synthesis and properties of sildenafil isostere.
Su Z, Zhang Q, Zhao Q, Liu W, Zhao T, Wang H, Li J, Xu J. Su Z, et al. Arch Pharm (Weinheim). 2021 Oct;354(10):e2100145. doi: 10.1002/ardp.202100145. Epub 2021 Jun 15. Arch Pharm (Weinheim). 2021. PMID: 34131943
A total of 28 compounds, containing alkyl and aryl groups at the 1-N and 3-C positions on the pyrazole ring, and also bearing different alkyl substituents on the piperazine ring were synthesized. Four compounds (4d, 5d, 6d, and 5o) were found to have better inhibitory acti …
A total of 28 compounds, containing alkyl and aryl groups at the 1-N and 3-C positions on the pyrazole ring, and also bearing different alky …
Using Chiplet Encapsulation Technology to Achieve Processing-in-Memory Functions.
Tian W, Li B, Li Z, Cui H, Shi J, Wang Y, Zhao J. Tian W, et al. Micromachines (Basel). 2022 Oct 20;13(10):1790. doi: 10.3390/mi13101790. Micromachines (Basel). 2022. PMID: 36296142 Free PMC article. Review.
Chiplet combines processor cores and memory chips with advanced packaging technologies, such as 2.5D, 3 dimensions (3D), and fan-out packaging. This improves the quality and bandwidth of signal transmission and alleviates the "storage wall" problem. ...Second, the Chiplet …
Chiplet combines processor cores and memory chips with advanced packaging technologies, such as 2.5D, 3 dimensions (3D), and fan-out …
5D-QSAR studies of 1H-pyrazole derivatives as EGFR inhibitors.
Qin D, Zeng X, Zhao T, Cai B, Yang B, Tu G. Qin D, et al. J Mol Model. 2022 Nov 7;28(12):379. doi: 10.1007/s00894-022-05370-x. J Mol Model. 2022. PMID: 36342554
Several EGFR inhibitors were approved in cancer treatment. Comparatively, 5D-QSAR is a new methodology which considers an ensemble of different induced-fit models. Based on 1H-pyrazole derivatives as EGFR inhibitors, a 5D-QSAR was studied in which the method of quas …
Several EGFR inhibitors were approved in cancer treatment. Comparatively, 5D-QSAR is a new methodology which considers an ensemble of …
741 results